http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108419436-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108419436-B |
| titleOfInvention | Substituted pyrazine carboxamide compound, composition containing compound and application of compound |
| abstract | The invention provides a substituted pyrazine carboxamide compound, a composition containing the compound and application of the compound, wherein the substituted pyrazine carboxamide compound is a pyrazine carboxamide compound shown as a formula (I), or a crystal form, pharmaceutically acceptable salt, prodrug, stereoisomer, hydrate or solvent compound of the pyrazine carboxamide compound. The substituted pyrazine carboxamide compound and the composition containing the compound disclosed by the invention have excellent inhibitory activity on EGFR kinase, have better pharmacokinetic parameter characteristics, and can improve the drug concentration of the compound in animal bodies so as to improve the drug curative effect and safety. Formula (I). |
| priorityDate | 2016-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 87.