| abstract |
The invention provides an amide compound, its pharmaceutical composition, preparation method and application, belonging to the field of medicine. The structure of the amide compound is shown in formula I, and its preparation method comprises: carrying out condensation reaction of compound II and compound III in an organic solvent under alkaline conditions. The amide compound or a pharmaceutically acceptable salt thereof has long-acting sensory and/or motor blocking activity, and can be used to prepare long-acting local anesthetics or analgesics, with long drug effect time and small side effects, and can be used for medication. High security. |