abstract |
N-diethylaminoacetyl-2,6-dimethylaniline derivative, preparation method and use. The structure of said derivative is shown in formula (I). When preparing, the corresponding quaternary ammonium salt intermediate compound can be prepared from N-diethylaminoacetyl-2,6-dimethylaniline and halogenated compounds first, and then the corresponding 2-methoxy-4-substituted phenol derivative It is obtained after the reaction of similar raw materials. The derivative can be used as a local anesthetic or analgesic drug with long-acting and motor-sensory separation, can exert a reversible and long-lasting local anesthetic effect in the living body, and has no effect on motor function within a certain dose range, and has ideal movement and sensation Detached blocking effect. |