http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108383682-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ee33b0e3e7398cf6fc957eeee59d510 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6bc8320349ec24ecc22176c1472a482a |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C17-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C25-13 |
| filingDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f43eb358e6400e142494404daa4c8b57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d148e9ca3165d6aec78c83a1c17343e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa4e68ceb25880c14e3e0aa5477c0bc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2fe02c8891a17bf6efd7fdf7bb4e1828 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a9e6a7e086fff8a6a5bd130266c8ea4 |
| publicationDate | 2018-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-108383682-A |
| titleOfInvention | A kind of method utilizing microreactor to prepare difluorobenzyl bromide continuously |
| abstract | The invention provides a method for continuously preparing difluorobenzyl bromide by using a microreactor, continuously injecting 4'-cyclopentyl-3,5-difluorobiphenyl solution into the upper chamber of the first microreactor, The lower chamber of the first microreactor continuously injects n-butyllithium solution to carry out the first reaction; the upper chamber of the second microreactor continuously injects the first reaction material obtained, and the lower chamber of the second microreactor Continuously inject haloalkane solution for the second reaction to obtain difluorobenzyl bromide. The present invention utilizes a microreactor to prepare difluorobenzyl bromide in a continuous manner. The mass transfer efficiency of the microreactor is very high, and it is a continuous reaction, which can effectively shorten the time-consuming process and improve production efficiency; at the same time, the reactants can be fully contacted and have It is beneficial to improve the reaction conversion rate, thereby increasing the product yield. The experimental results of the examples show that the yield of difluorobenzyl bromide can reach 85% and the process time can be shortened to 62.5 minutes by using the microreactor to continuously prepare difluorobenzyl bromide. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020164217-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109734566-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110294769-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110294769-B |
| priorityDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.