http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107115831-A

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filingDate 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b45e2d5f7bc328f2104856c6d6d5dca9
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publicationDate 2017-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107115831-A
titleOfInvention A kind of preparation method of microreactor and dihydrostreptomycin sulfate based on microreactor
abstract The present invention relates to a kind of microreactor and the dihydrostreptomycin sulfate based on microreactor preparation method, belong to semisynthetic antibiotics preparing technical field.The invention provides a kind of microreactor, the microreactor includes upper chamber and lower chambers, and two chambers are separated by microporous barrier up and down.In microreactor, upper chamber is continuously injected into solution of potassium borohydride, streptomycin sulfate solution is continuously injected into microreactor lower chambers, solution of potassium borohydride is carried out hydrogenation reaction into streptomycin sulfate solution by microporous barrier vertical distribution and obtain dihydrostreptomycin, desalination removes Boratex, and regulation pH obtains dihydrostreptomycin sulfate for 3~7.Using above-mentioned microreactor prepared by dihydrostreptomycin sulfate, simple to operate, cost is low, and the reaction time is short, successive reaction can be achieved.
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priorityDate 2017-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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Total number of triples: 30.