| abstract |
The invention discloses a condensed heterocyclic compound, its preparation method, pharmaceutical composition and application. The condensed heterocyclic compound is shown in formula II. The preparation method of the fused heterocyclic compound and/or its pharmaceutically acceptable salt of the present invention includes a synthetic route. The present invention also provides the pharmaceutical composition of the fused heterocyclic compound, which contains the fused heterocyclic compound shown in formula II, its pharmaceutically acceptable salt, hydrate, solvate, polymorph and One or more of its prodrugs, and a pharmaceutically acceptable carrier; and relate to the fused heterocyclic compound and/or pharmaceutical composition in the preparation of kinase inhibitors, and preparation for the prevention and treatment of kinase-related diseases application in medicines. The fused heterocyclic compound of the invention has selective inhibitory effect on PI3Kδ, and can be used for preparing medicines for preventing and treating cell proliferation diseases such as cancer, infection, inflammation or autoimmune diseases. |