http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106187891-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D219-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D219-12 |
filingDate | 2016-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-106187891-B |
titleOfInvention | Compound and the preparation method and application thereof with anti-Alzheimer disease effect |
abstract | The invention discloses a series of compounds with anti-Alzheimer disease effect, the present invention is using ortho-aminobenzoic acid as raw material, by obtaining 9- chloro- 1 with hexamethylene reactive ketone, 2,3,4 tetrahydro acridines, then 9- (beta-amino ethylenediamine) -1 is obtained with reacting ethylenediamine, 2,3,4- tetrahydro acridines;Then a series of compounds with anti-Alzheimer disease effect are prepared with cinnamic acid and its derivatives reaction again;Entire technological design is reasonable, and yield is high, and by-product is few, at low cost, and the compound purity being prepared is high, has good anti-Alzheimer disease effect, it can be achieved that industrialized production. |
priorityDate | 2016-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 170.