abstract |
The preparation method of vinyl sulfone derivatives, the vinyl sulfone derivatives have the structure of general formula I, the preparation method is to react compound i and divinyl sulfone in the presence of a catalyst, wherein said R is selected from H Or C 1-8 alkyl; n≥1 and n is an integer; the catalyst is selected from triarylphosphine compounds or nitrogen-containing heterocyclic compounds. Under the action of the selected catalyst of the present invention, the product can be quickly reacted at room temperature. The method has the advantages of mild conditions, fast reaction speed, high conversion rate, etc., and the prepared product has the advantages of hydrolysis resistance, alkali resistance, broad-spectrum reaction, etc., and has high application value. |