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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06
filingDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105732660-B
titleOfInvention The preparation method of lavo-ofloxacin intermediate
abstract The present invention relates to a kind of preparation method of lavo-ofloxacin intermediate, by by the carboxylic acid, ethyl ester of 3 methyl of (S) 9,10 difluoro, 7 oxo 2,3 dihydro 7H pyridos [1,2,3 △] 1,4 benzoxazine 6(Formula III)In the in the mixed solvent of organic solvent and water, hydrolyze, and further obtained with acid reaction under alkaline conditions.The method of the present invention has post processing simple, and impurity content is low, and solvent for use low toxin.
priorityDate 2014-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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