http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103755722-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7fc71786fed62b920292ffb6731d2e13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-06 |
| filingDate | 2013-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e62e2c51be8240f668cb7f9922802fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea63e6ec30ca4aeac368c88f161d7489 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_596b9df2d6b0450747323f2cab782bea |
| publicationDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103755722-A |
| titleOfInvention | A kind of synthetic method of levofloxacin and ofloxacin |
| abstract | This method provides a synthetic method of levofloxacin and ofloxacin, using S-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[ 1,2,3-Δ]-[1,4]-Benzoxazine-6-carboxylate or 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H -Pyrido[1,2,3-Δ]-[1,4]-benzoxazine-6-carboxylate as raw material, improved final hydrolysis, N-methylpiperazine substitution two steps, through "one pot method" synthesis. The method of the invention is a more simple, economical and efficient one-step synthesis method. At the same time, the specific impurities produced in related processes are separated, identified, and prepared. This method has high raw material utilization rate, high yield and purity, simplifies the original steps, shortens the reaction cycle, and is convenient for industrial production. At the same time, a detection method for related impurities is proposed to distinguish the process from other process products. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104292159-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104292159-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104277052-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105732660-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105732660-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111620889-A |
| priorityDate | 2013-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.