http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105622526-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de020b7dcbcaf745ca743fa95fa94853 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D241-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D241-20 |
| filingDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_325e364310fef1ebff59552a9660344b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_029167fdfd4bda20b5cddbaac59e2722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42586856112524b42973884fb48962e0 |
| publicationDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-105622526-A |
| titleOfInvention | A kind of preparation method of 2-aminopyrazine derivative |
| abstract | The invention relates to a preparation method of 2-aminopyrazine derivatives, belonging to the technical field of organic synthesis. Use 2-cyanopyrazine as raw material, add sodium hypochlorite solution and alkali, react to obtain 2-aminopyrazine, and then carry out bromination reaction to obtain 2-amino-3,5-dibromopyrazine, and then use 2-amino-3 , 5-dibromopyrazine is used as raw material to carry out substitution reaction with morpholine, piperazine and pyrrole respectively to obtain 2-amino-5-bromo-3-morpholinopyrazine, 2-amino-5-bromo-3- Piperazinylpyrazine and 2-amino-5-bromo-3-pyrrolidinylpyrazine. The invention uses 2-cyanopyrazine as a raw material to prepare different 2-aminopyrazine derivatives, the raw material is cheap and easy to obtain, the operation is simple, and the yield of the target product is high. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110878056-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108570011-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2022129018-A1 |
| priorityDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.