abstract |
The present invention provides a compound of formula (I), and its pharmaceutically acceptable ester, amide, solvate or salt, wherein R 1 , R 2 , R 3 , R 4 and R 5 have the meanings given in the specification, and the compound is wherein Useful in the treatment of diseases where inhibition of protein or lipid kinases (eg PI3-K and/or mTOR) is desired and/or required, and in particular in the treatment of cancer or proliferative diseases. |