http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105601617-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 |
filingDate | 2016-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105601617-B |
titleOfInvention | A kind of neighbour's diazacyclo compound and the preparation method and application thereof |
abstract | The present invention relates to a kind of adjacent diazacyclo compounds and the preparation method and application thereof.Neighbour's diazacyclo compound, shown in structural formula such as formula (I): The present invention also provides the preparation method and application of above-mentioned adjacent diazacyclo compound.Present invention firstly discovers that N- ((4- chlorphenyl) -5- (Trifluoromethyl-1 H- pyrazolyl)) -3- cyano -4- (4- morpholine piperidyl) benzamide, and find that the compound is a kind of completely new, effective antagonist for inhibiting inflammatory factor IL-17 downstream signaling pathway, it can be used for treating the disease relevant to IL-17 signal pathway inhibitor such as inflammatory conditions, autoimmune disease, proliferative diseases and cancer. |
priorityDate | 2016-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 213.