abstract |
Compounds of formula (I) are provided, wherein: Ring A and Ring B are each independently an optionally substituted 5-6 membered monocyclic aryl or heteroaryl; one of X, Y, and W is CH and the other two are N; and Z is H or -C(R1)(R2)(R3). These compounds are inhibitors of isocitrate dehydrogenase 2 (IDH2) mutants useful in the treatment of cancer. |