http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105434348-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61
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filingDate 2015-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105434348-B
titleOfInvention A kind of phycocyanin-glucan-cordycepin micella of the anti-cancer of the brain and its preparation method and application
abstract The invention discloses phycocyanin-glucan-cordycepin micellas of a kind of anti-cancer of the brain and its preparation method and application.Phycocyanin-glucan-cordycepin the micella is first to use the method for Maillard reaction that phycocyanin is grafted on glucan, forms phycocyanin-glucan complex;It is self-assembly of micella inside cordycepin package to phycocyanin by the mechanism of self assembly again and is prepared.Above-mentioned phycocyanin-glucan-cordycepin micella provided by the invention can pass through blood-brain barrier to reach at tumour, there is significant inhibiting effect to brain cancer cell, and drug can slow release, retention action time in blood is longer, it is made finally passively to be accumulated at tumor tissues.In addition, the material for preparing the micella derives from natural constituent, any organic solvent is not added in building-up process, has good biocompatibility and biodegradability, has prodigious potentiality and foreground in terms of the treatment use of the cancer of the brain.
priorityDate 2015-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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