| abstract |
The invention belongs to the technical field of medicine, and relates to the preparation and application of a series of curcumin analogues, which have structures such as formula I, formula II and formula III, wherein R, R 1 and R 2 are as described in the specification. The pharmaceutically acceptable salts and solvates of the curcumin analogues, as well as the medicines containing the curcumin analogues or pharmaceutically acceptable salts thereof as active ingredients, can be used for treating cancer. The curcumin analogs and their medicinal salts described in the invention have good anticancer activity, and the preparation method is simple, feasible and easy to operate. |