http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105194666-B

Outgoing Links

Predicate Object
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
filingDate 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-105194666-B
titleOfInvention A kind of hepatitis B vaccine agonist compositions and its application
abstract The invention discloses a kind of hepatitis B vaccine agonist compositions and its applications, are related to hepatitis B vaccine.A kind of hepatitis B vaccine agonist compositions are made of Louis-polyacrylamide-biotin, polyinosinic acid-polycytidylic acid, oligodeoxynucleotide;Wherein, the Louis-polyacrylamide-biotin components are that the polyacrylamide of 30kd contains 5% mole of biotin and 20% mole of carbohydrate;The sequence of the oligodeoxynucleotide is:5 '-tcgacgttcgtcgttcgtcgttc-3 ', whole thio-modification.The present invention stimulates the high of corresponding receptor to express by the agonist of tri- kinds of receptors of DC-SIGN, TLR3, TLR9, to improve the antigen presentation function of DC, promotes the Th1 immune responses of body.
priorityDate 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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