http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105194666-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
filingDate | 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-105194666-B |
titleOfInvention | A kind of hepatitis B vaccine agonist compositions and its application |
abstract | The invention discloses a kind of hepatitis B vaccine agonist compositions and its applications, are related to hepatitis B vaccine.A kind of hepatitis B vaccine agonist compositions are made of Louis-polyacrylamide-biotin, polyinosinic acid-polycytidylic acid, oligodeoxynucleotide;Wherein, the Louis-polyacrylamide-biotin components are that the polyacrylamide of 30kd contains 5% mole of biotin and 20% mole of carbohydrate;The sequence of the oligodeoxynucleotide is:5 '-tcgacgttcgtcgttcgtcgttc-3 ', whole thio-modification.The present invention stimulates the high of corresponding receptor to express by the agonist of tri- kinds of receptors of DC-SIGN, TLR3, TLR9, to improve the antigen presentation function of DC, promotes the Th1 immune responses of body. |
priorityDate | 2015-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.