http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104926807-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b1eac93fa8426bfd541c9e14e11860
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14
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filingDate 2015-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c47ed2aec22b316ceaedc04aaf3f9aa7
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publicationDate 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104926807-A
titleOfInvention A rivaroxaban-related substance "diamine" and its synthesis method
abstract The invention belongs to the field of medical technology, and discloses the structure of "diamine" in the synthesis of rivaroxaban-related substances and its synthesis method, including the following steps: (1) taking rivaroxaban as a starting material by hydrolyzing the morpholinone ring Compound 3 was obtained. (2) 5-chlorothiophene-2-formyl chloride was synthesized from 5-chlorothiophene-2-carboxylic acid and thionyl chloride as starting materials. (3) Compound 3 and compound 5 were condensed to generate compound 6. (4) Compound 6 was condensed with methylamine to obtain rivaroxaban-related substance “diamine”. The synthesis method has easy-to-obtain raw materials and simple operation.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106432218-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110818700-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106432218-B
priorityDate 2015-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 22.