http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104725375-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6a6f422b091ba12ea61d4adbf1b0e8e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e656a96473b4d8b2ccb9b8fdbeed2f85 |
| publicationDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104725375-A |
| titleOfInvention | A method for preparing triazoloisoquinoline derivatives |
| abstract | The invention discloses a preparation method of triazoloisoquinoline derivatives. In an organic solvent environment, a rhodium catalyst and a copper salt are used as catalysts. Under the action of an oxidizing agent, 1,2,3-triazole derivatives and Cyclooxidative reaction of internal alkynes to obtain triazoloisoquinoline derivatives in one pot. The method of the invention uses 1,2,3-triazole derivatives and internal alkynes as raw materials, the reaction raw materials are cheap and easy to obtain, the preparation method is simple, and a small amount of rhodium catalyst and copper salt are used as catalysts, which can greatly reduce the cost. The method of the invention can be used to synthesize a series of triazoloisoquinoline derivatives, and the prepared products have biological activities such as anti-tumor, anti-inflammatory and anti-bacterial, and can be used as important intermediates for the total synthesis of alkaloids. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478623-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106478623-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109020972-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109020972-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108395412-A |
| priorityDate | 2015-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.