http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570510-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ea9ca85ef5df84e6fe5fa66dc61e404 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C41-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C41-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C43-225 |
| filingDate | 2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bde41ea11e077730b6bb099d7b739a58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63111ba395d44ceacdabd057b84dce68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f6c6529c30944fd16790c04c4e4c885 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75c5fcb6738a67d128b8b8328f2a0afa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22eef5c4b1ff7068562ae3aed5cedb56 |
| publicationDate | 2014-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103570510-A |
| titleOfInvention | One-pot synthesis method for 5-bromo-2-chloro-4'-ethoxy diphenylmethane |
| abstract | The invention discloses a one-pot synthesis method for 5-bromo-2-chloro-4'-ethoxy diphenylmethane. The method comprises the following continuous steps of: taking 2-chloro-5-bromobenzoic acid as a raw material, reacting it with thionyl chloride to generate 2-chloro-5-bromobenzoyl chloride, and adding an organic solvent, Lewis acid, phenetole and borohydride to undergo Friedel-Crafts acylation reaction and hydroboration reduction reaction so as to obtain the 5-bromo-2-chloro-4'-ethoxy diphenylmethane. The process involved in the invention has the advantages that the same Lewis acid is used as a catalyst in the Friedel-Crafts acylation reaction and the hydroboration reduction reaction, so that the catalyst consumption is greatly reduced, the operation is simple, and the intermediate needs no separation and purification. By effectively controlling the reaction conditions, and the charging sequence and proportion, the 5-bromo-2-chloro-4'-ethoxy diphenylmethane can be synthesized by one step, and fewer three wastes are discharged, the solvent recovery effect is good, and the production cost is low. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115124425-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105294624-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662166-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105061373-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115124425-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112920030-A |
| priorityDate | 2012-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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