http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103360299-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 |
| filingDate | 2012-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103360299-B |
| titleOfInvention | The preparation method of the isomer of trandolapril intermediate |
| abstract | The invention discloses the preparation method of the isomer of trandolapril intermediate as shown in formula C; this method specifically discloses the (R with content higher than 90%; S; S) octahydro indole 2 carboxylic acid (shown in formula A) is initiation material; obtain isomer mixture C and D of corresponding trandolapril intermediate through configuration reversal, upper benzyl protection, then the preparation method being isolated to the isomer of the trandolapril intermediate as shown in formula C：Technical scheme Chinese style A is after configuration reversal, the content of formula B compound is significantly deducted a percentage, largely facilitate the isomer of preparation other intermediate follow-up, aforesaid compound is used for preparing the medicine of anti-cardiovascular disease and the quality for controlling these medicines. |
| priorityDate | 2012-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.