| abstract |
The present invention provides specific chemical entities and methods for modulating skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T and skeletal muscle, including Fragments and isoforms thereof, and methods for sarcomeres, and methods for treating obesity, sarcopenia, wasting syndrome, frailty, cachexia, muscle spasticity, postoperative and posttraumatic muscle weakness, neuromuscular disease and other conditions method. |