abstract |
The present invention relates to a class of pyridine compounds having c-Met and/or ALK inhibitory activity and their pharmaceutically acceptable salts or pharmaceutically acceptable solvates represented by the following general formula, and their preparation method, comprising the The pharmaceutical composition of the compounds, and the preparation of these compounds for the prevention or treatment of abnormal cell proliferation, morphological changes and movement related to the hepatocyte growth factor receptor (HGFR) and/or anaplastic lymphoma kinase (ALK) in the organism Hyperfunction and other related diseases, as well as medicines for diseases related to angiogenesis or cancer metastasis, especially for the treatment or prevention of tumor growth and metastasis. |