http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102249921-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C29-143 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C33-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 |
| filingDate | 2010-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102249921-B |
| titleOfInvention | 2-(2,3-3,5-dimethylphenyl) diester malonate, Preparation Method And The Use |
| abstract | The invention discloses a kind of 2-(2, 3-3,5-dimethylphenyl) diester malonate, its preparation method and the intermediate 1-(2 for the synthesis of hydrochloric acid Dexmedetomidine thereof, 3-3,5-dimethylphenyl) purposes of ethanol, the present invention is with 2, 3-mesitylenic acid is starting raw material, 2 are made through chloride, after 3-dimethyl benzoyl chloride, obtained 2-(2 is reacted with diester malonate under triethylamine and Magnesium Chloride Anhydrous exist, 3-3,5-dimethylphenyl) diester malonate, described 2-(2, 3-3,5-dimethylphenyl) diester malonate sulphuric acid hydrolysis obtains 1-(2, 3-3,5-dimethylphenyl) ethyl ketone, again through the obtained 1-(2 of reductive agent reduction, 3-3,5-dimethylphenyl) ethanol.The inventive method is easy and simple to handle, starting material are cheap and easy to get, reaction conditions is gentle, gained finished product purity is high, without the need to special separation and purification, is suitable for large-scale production. |
| priorityDate | 2010-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.