http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102218063-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_617e2c80b28c41a94da1980f494891a6 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N30-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-10 |
| filingDate | 2011-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9f4e20eccd528ce4e6dcf2b445a0f62 |
| publicationDate | 2011-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-102218063-A |
| titleOfInvention | Preparation method and product of propiverine hydrochloride medicine and detection method thereof |
| abstract | The invention discloses a preparation method and product of propiverine hydrochloride and its detection method. The preparation method is as follows: firstly take diphenyl-chloroacetic acid-(1-methyl-4-piperidinol) ester Hydrochloride and n-propanol are synthesized to obtain the crude product of propiverine hydrochloride; then the crude product of propiverine hydrochloride is dissolved in alcohol, decolorized, filtered and crystallized to obtain the refined product of propiverine hydrochloride; finally, the crude product of propiverine hydrochloride is Wellin boutique and appropriate amount of auxiliary materials are made into various pharmaceutical dosage forms. The present invention not only simplifies the technological process, shortens the reaction time, effectively improves the yield of the product, but also greatly reduces the impurity content by improving the synthesis and refining process of propiverine hydrochloride and optimizing the detection method. Compared with the traditional synthesis method, the purity of the product avoids unsafe factors in the production process, reduces the cost of synthesis, and effectively reduces the toxic and side effects of traditional medicines for active bladder syndrome, providing patients with more reliable medicines. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4035668-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2014025569-A1 |
| priorityDate | 2011-04-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.