http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102161660-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7826e82a59639f553bfb024dfb2a0ea5 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 |
filingDate | 2010-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f8de7fe34f3cb0051a651f9d653cb46 |
publicationDate | 2011-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-102161660-A |
titleOfInvention | Preparation method of 2-(6-chloro-2-methylpyrimidinyl-4-amino)-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide |
abstract | The invention discloses a preparation method of a compound 2-(6-chloro-2-methylpyrimidinyl-4-amino)-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide shown in the formula (1). The method comprises the following steps: (1) preparing ethyl 2-(6-chloro-2-methylpyrimidinyl-4-amino)thiazole-5-carboxylate by using ethyl 2-aminothiazole-5-carboxylate and 2-methyl-4,6-dichloropyrimidine as a raw materials; (2) preparing 2-(6-chloro-2-methylpyrimidinyl-4-amino)thiazole-5-carboxylic acid by using ethyl 2-(6-chloro-2-methylpyrimidinyl-4-amino)thiazole-5-carboxylate as a raw material; and (3) preparing 2-(6-chloro-2-methylpyrimidinyl-4-amino)-N-(2-chloro-6-methylphenyl)-5-thiazolecarboxamide shown in the formula (1) by using 2-(6-chloro-2-methylpyrimidinyl-4-amino)thiazole-5-carboxylic acid and 2-chloro-6-methylaniline as raw materials. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107043375-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107043375-A |
priorityDate | 2010-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 21.