| abstract |
The present invention relates to be used for the method and apparatus of the very large-scale F ET array of analysis measurement.Can utilize the conventional cmos manufacturing technology to come manufacturing chemistry FET (for example ISFET) array based on improved FET pixel and array design, this design helps obviously little Pixel Dimensions and closely spaced array in sensitivity that improves measurement and accuracy.Improved array control technology provides the rapid data collection from large-scale closely spaced array.This array is used in the existence that detects dissimilar analytes in chemistry widely and/or the bioprocess and/or the change of concentration.In an example, chemical FET helps the determined dna sequence technology based on the binding events that monitoring pH (pH) changes, the variation of other analyte concentrations and/or the chemical process synthetic with relating to DNA are relevant. |