abstract |
The present invention relates to can be used for the RNA disturbance target point of 42 different target HBV for the treatment of hepatitis B virus infection, can be used for preparing the medicine that can be used for treating hepatitis B virus infection.The invention provides and can be used for expressing the siRNA of target HBV and/or the recombinant expression vector of miRNA and/or ribozyme and/or antisense oligonucleotide.The present invention relates to have suppress HBV viral gene expression ability to express and/or be imported into RNA disturbance target point provided by the invention serve as according to the siRNA that obtains and/or the cell of miRNA and/or ribozyme and/or antisense oligonucleotide and/or medicine. |