| abstract |
The invention discloses a mechanochemical preparation method for flavone compounds with a structure shown in a formula (II), which comprises the following steps: 1-(2'-hydroxy phenyl)-3-aryl-1, 3-propanedione with a structure shown in a formula (I) is taken as a raw material, hydrosulfate is taken as a catalyst, and silica gel is taken as a grinding aid to perform a ball grinding reaction in a closed ball grinding tank; and after the reaction is finished, a reaction mixture is separated and purified to obtain the flavone compounds with the structure shown in the formula (II). The method has the advantages of short reaction time, generally higher reaction yield, safe and reliable production, low production cost, simple post-treatment, small pollution and so on, and is the preparation method for the flavone compounds with better popularization and application prospects. |