abstract |
Pilocarpine derivatives corresponding to the formula of the figure in which R1 signifies an alkyl group, R2 and R3 signify H or an alkyl group, R4 and R5 signify together = O, = S or = NR, or else R4 signifies H and R5 H, OH or OR. These compounds are useful for the treatment of senile dementia, Alzheimer's disease, states of confusion in the elderly, myasthenia gravis, schizophrenia, mania and glaucoma. |