http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_fca3db5d3bb77d407077c9ffb33821f8
Outgoing Links
Predicate | Object |
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family-name | Liu Yun Liu |
name | Yun Liu |
given-name | Yun |
organization-name | College of Animal Science and Technology, Southwest University, Chongqing 400715, China Department of Radiology Chongqing Special Equipment Inspection and Research Institute, Chongqing 401121, China; Key Laboratory of Electromechanical Equipment Security in Western Complex Environment for State Market Regulation, Chongqing 401121, China Beijing Novo Nordisk Pharmaceuticals Science and Technology Co., Ltd., 29 Life Science Park Road, Beijing, China Department of Geratology, First Affiliated Hospital, Nanjing Medical University, Nanjing - China Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill 27599, North Carolina, United States Shenyang Hehe Medical Test Institute, Shenyang, Liaoning Province 100200, China. Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou Jiangsu 221116, P. R. China Department of Laboratory Medicine Affiliated Hospital of Xuzhou Medical University Xuzhou China Beijing Institute of Radiation Medicine, China Shanghai Key Laboratory of Magnetic Resonance East China Normal University Shanghai China Department of Clinical Veterinary Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang 150000, P.R. China Division of Spinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Guangxi Zhuang Autonomous Region, China. MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University, Shanghai, China NIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States; Department of Chemical Engineering, University of Delaware, Newark, Delaware 19716, United States Department of Mechanical Engineering, University of Maryland, College Park, Massachusetts 20742, United States Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy and Joint Research Institution of Altitude Health and National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China Department of Nephrology Huai'an Second People's Hospital and the Affiliated Huai'an Hospital of Xuzhou Medical University Huai'an China 0 Cadre Wards of Neurology Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University Department of Forensic Medicine North Sichuan Medical College Nanchong Sichuan China; Sichuan Key Laboratory of Medical Imaging North Sichuan Medical College Nanchong Sichuan China Department of General Surgery, Beijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China Department of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China Department of Cardiology the Eighty‐first Hospital of PLA Affiliated with Anhui Medical University Nanjing China National Key Laboratory of High-efficiency Utilization of Coal and Green Chemical Engineering, Ningxia University, Yinchun, 750021, China Department of Radiology Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China Phase I Clinical Trial Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, China. Institutes of Biomedical Sciences, Fudan University, Shanghai, China Australian Institute for Bioengineering and Nanotechnology The University of Queensland Brisbane QLD 4072 Australia Department of Optoelectronic Science & Technology, College of Elecrical & Information Engineering, Shaanxi University of Science & Technology, Xi’an 710021, China Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, High Magnetic Field Laboratory, HFIPS, Chinese Academy of Sciences, Hefei 230031, China Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Hefei Institutes of Physical Science, Chinese Academy of Sciences; Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei, Anhui, PR China; Department of Geratology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy; Department of Genetics & Department of Medical Microbiology, School of Basic Medical Sciences; Research Center of Basic Medical Sciences; Tianjin Medical University, Tianjin 300070, China Department of Hepatic Surgery, Zhongshan Hospital Affiliated to Xiamen University, Xiamen, Fujian 361004, P.R. China Department of Chemistry, University of California, Riverside, California 92521, United States Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390 Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Department of Family Planning, Beijing, China Division of Spinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, P.R. China Department of Laboratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China Department of Clinical Laboratory Women's Hospital of Nanjing Medical University (Nanjing Maternity and Child Health Care Hospital) Nanjing China Department of Chemistry, University of Washington, Seattle, Washington 98195, United States Experiment Center of Teaching & Learning, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Department of General Surgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi 030001, P.R. China Schoole of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China Department of Pharmacy, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu 222002, P.R. China Key Laboratory of Biorheological Science and Technology, Ministry of Education, College of Bioengineering, Chongqing University, Chongqing 400044, P. R. China Department of Cardiothoracic Surgery, China Three Gorges University,Yichang, Hubei, China. Department of Clinical Pharmacology The First People's Hospital of Lianyungang Lianyungang Affiliated Hospital of Xuzhou Medical University Lianyungang P. R. China Jiangsu Key Laboratory of Green Synthetic for Functional Materials and School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou 221116, Jiangsu, PR China School of Environmental Science and Engineering, Sun Yat-Sen University, Guangzhou 510006, China Key Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institutes of Chinese Material Medica, Shanghai University of Traditional Chinese Medicines, Shanghai 201203, China. daocaoren_0321@hotmail.com Institute for Computational Medicine, Department of Biochemical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA. The NIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-6100, United States; Department of Chemical Engineering, University of Delaware, Newark, Delaware 19716, United States Guizhou Key Laboratory of Anesthesiology and Organ Protection, Zunyi Medical College, Zunyi 563000, China; Research Center for Medicine & Biology, Zunyi Medical College, Zunyi 563000, China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China Key Laboratory of Soil Environment and Pollution Remediation, Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, Jiangsu, China; Civil and Environmental Engineering, University of California, Los Angeles, Los Angeles 90095, California, United States; University of Chinese Academy of Sciences, Beijing 100000, Hebei, China Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China Department of Environmental Science and Engineering, Xiangtan University, Xiangtan 411105, China; The Key Lab of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, Guangzhou 510006, China Google AI Healthcare School of Environmental Science and Engineering, Sun Yat-sen University, Guangzhou 510006, China Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry Wuhan University Wuhan 430072 China Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599, USA. Department of Dermatology,1 Department of Nephrology Guangzhou Red Cross Hospital, Medical School of Jinan University Guangzhou China; Guangzhou Institute of Disease‐Oriented Nutritional Research Guangzhou Red Cross Hospital, Medical School of Jinan University Guangzhou China Xinxiang Key Laboratory of Tumor Migration and Invasion Precision Medicine Xinxiang Medical University Xinxiang, Henan Province China; Henan Key Laboratory of immunology and targeted therapy School of Laboratory Medicine Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine School of Laboratory Medicine Xinxiang Medical University Xinxiang, Henan Province China Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials and Institute of Chemistry and Chemical Engineering; Jiangsu Normal University; Xuzhou 221116; P. R. China Institutes of Biomedical Sciences Fudan University Shanghai China; Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education) Bio‐X Institutes Shanghai Jiao Tong University Shanghai China Horticultural Research Institute, Guangxi Academy of Agricultural Sciences, Nanning, China Center for Neutron Science; Department of Chemical and Biomolecular Engineering; University of Delaware; Newark, USA; NIST Center for Neutron Science Guangzhou Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China; Department of Nephrology, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, China School of Microelectronics, Dalian University of Technology, Dalian, 116024, PR China Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, USA Research School of Chemistry; The Australian National University; Canberra; Australia Department of Diving Medicine, The Second Military Medical University, 800 Xiangyin Road Shanghai 200433; Department of Orthopedics The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China; Research Centre for Regenerative Medicine, Guangxi Key Laboratory of Regenerative Medicine Guangxi Medical University Nanning Guangxi China National Institute of Standards and Technology 7 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA; University of Delaware 8 Department of Chemical Engineering, , Newark, Delaware 19716, USA School of Biomedical Sciences, The University of Western Australia, Perth, WA 6009, Australia; Department of Orthopaedics, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China Department of Anesthesiology, Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China Department of Pediatric Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin’s Clinical Research Center for Cancer, Tianjin, China From Google AI Healthcare, Google Research, Mountain View, California (Drs Liu, Kohlberger, Norouzi, Dahl, Peng, Hipp, and Stumpe); and Laboratory Department, Naval Medical Center, San Diego, California (Drs Smith, Mohtashamian, and Olson). Department of Entomology National Taiwan University Taipei Taiwan Center for Reproductive Medicine 900th Hospital of Joint Logistics Support Force of PLA Fuzhou China Research School of Chemistry The Australian National University Canberra ACT 2601 Australia School of Chemistry, The University of Sydney, NSW 2006, Australia, NIST Center for Neutron Research, Gaithersburg, Maryland 20899-8562, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742-2115, and Indiana University Cyclotron Facility, Bloomington, Indiana 47408 Shanghai University of Traditional Chinese Medicine Shanghai 201203, China SPH Xing Ling Science & Technology Pharmaceutical Co., Ltd. Shanghai 201703, China. Research School of Chemistry; Australian National University; Canberra; Australia Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101, China, and Graduate School of the Chinese Academy of Sciences, Beijing 100101, China Department of Radiology; Qilu Hospital of Shandong University; Jinan China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, China; College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China University of Delaware 4 Department of Chemical Engineering, , Newark, Delaware 19716, USA; National Institute of Standards and Technology 5 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA Key Laboratory of Protein Chemistry and Developmental Biology of Educational Ministry of China, College of Life Sciences, Hunan Normal University, Changsha, Hunan 410081, China. Research School of Chemistry Australian National University College of Science Building 137, Sullivans Creek Rd Acton ACT 2601 Australia College of Bioresources Chemical and Materials Engineering, Shaanxi University of Science and Technology, Xi’an 710021, China; National Demonstration Center for Experimental Light Chemistry Engineering Education, Shaanxi University of Science and Technology, Xi’an 710021, China; Institute of Biomass and Functional Materials, Shaanxi University of Science and Technology, Xi’an 710021, China Peking University Medical and Health Analytical Center, Peking University Health Science Center, Beijing 100191, P.R. China Beijing National Laboratory for Molecular Sciences Key Laboratory of Polymer Chemistry and Physics of Ministry of Education Center for Soft Matter Science and Engineering College of Chemistry and Molecular Engineering Peking University Beijing 100871 China Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing 210096, China Department of Computer Science and Engineering, East China University of Science and Technology, Shanghai 200237, China Department of Information, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China Beijing National Laboratory for Molecular Sciences (BNLMS) Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China Xi'an Chest Hospital, Xi'an 710061, Shaanxi, China. Department of Nutritional Sciences, University of Michigan School of Public Health, Ann Arbor, MI, USA Department of Clinic Veterinary Medicine, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China. Department of Molecular Biology and Genetics, Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. Contribution from the Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-3400, and Institute of Geochemistry, Chinese Academy of Sciences, 46 Guanshui Road, Guiyang, Guizhou 550002, P. R. China Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University , Shanghai 200135 , P.R. China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics , Shanghai 200135 , P.R. China Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; Bio-X Center, Shanghai Jiao Tong University, Shanghai 200030, China Department of Obstetrics, Nankai Hospital, Tianjin, China Experiment Center of Teaching & Learning; Shanghai University of Traditional Chinese Medicine; Shanghai 201203; China Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, China. Department of Gastroenterology and Hepatology Zhongshan Hospital Fudan University Shanghai China Key Laboratory of Comparative Medicine, Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China Department of Orthodontics, Hangzhou Dental Hospital. Hangzhou 310005,Zhejiang Province,China. E-mail:liuyun0825@126.com. Department of Diving Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, P.R. China. Centre for Catalysis Research and Innovation and Department of Chemistry, University of Ottawa, 10 Marie Curie, Ottawa K1N 6N5, Canada School of Electronic and Information Engineering, Beijing Jiaotong University 1 , Beijing 100044, China; Key Laboratory of Communication and Information Systems (Beijing Jiaotong University), Beijing Municipal Commission of Education 2 , Beijing 100044, China Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455-0431, and Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300 Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China Department of Chemistry, University of Texas at San Antonio, San Antonio, Texas 78249-0698, NIST Center for Neutron Research, Gaithersburg, Maryland 20899-6100, Department of Chemistry, University of Texas-Pan American, Edinburg, Texas 78539-2999, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742, and Department of Chemical Engineering, University of Delaware, Newark, Delaware 19716 School of Pharmacy Guangdong Medical University Zhanjiang 524023 P. R. China Guangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Zhanjiang 524023, China Department of Hematology, Fujian Medical University Union Hospital and Fujian Institute of Hematology, Fuzhou, Fujian, China (mainland) Australian Institute for Bioengineering and Nanotechnology University of Queensland St. Lucia Queensland 4072 Australia Shanghai Institute of Ceramics (SIC), Chinese Academy of Sciences (CAS), 1295 Dingxi, Changning, Shanghai 200050, China; Graduate University of Chinese Academy of Sciences, 19 Yuquanlu, Beijing, 100049, China Guizhou Provincial College-Based Key Laboratory for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical University , Zunyi, Guizhou , China; College of Basic Medicine, Zunyi Medical University , Zunyi, Guizhou , China; School of Forensic Medicine, Zunyi Medical University , Zunyi, Guizhou , China Institut Laue-Langevin, B.P. 156, F-38042 Grenoble Cedex 9, France; The NIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-6100; Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742; The Center for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831; Department of Chemistry, the University of Tennessee, Knoxville, Tennessee 37996-1600; and Neutron Scattering... Bioinformatics Institute, Agency for Science, Technology and Research (A*STAR), Singapore Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences and the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China Department of Neuroscience University of Texas Southwestern Medical Center Dallas TX Ministry of Education Key Laboratory of Eco-Environment of Three Gorges Reservoir Region, College of Resources and Environment, Southwest University, Chongqing 400716, China. liuyun19970205@163.com Department of Otolaryngology, Beijing Friendship Hospital, Capital University of Medical Sciences, Beijing 100050. Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, PR China State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals, Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences Sun Yat‐Sen University Guangzhou China Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, PR China Shenzhen Key Laboratory of Microbiology and Gene Engineering College of Life Sciences Nanhai Ave 3688 Shenzhen City Guangdong Province China 518060 Department of Medical Oncology, The First Affiliated Hospital of Hainan Medical University, Haikou, Hainan 570102, China School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, People's Republic of China; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390 Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA; Chemical & Biomolecular Engineering Department, University of Delaware, Newark, Delaware 19716, USA Department of Neuroscience, University of Texas Southwestern Medical Center , 6000 Harry Hines Blvd, Dallas, TX 75390-9111 , United States Shaanxi Provincial Hospital of Chinese Medicine Department of Infectious Diseases, , Xi’an 710003, Shaanxi Province , China State Key Laboratory of Oncogenes and Related Genes Shanghai Cancer Institute Renji Hospital Shanghai Jiaotong University School of Medicine Shanghai China Department of Gastroenterology Peking University People's Hospital Beijing China; Clinical Center of Immune‐Mediated Digestive Diseases Peking University People's Hospital Beijing China Department of Physiology, Faculty of Basic Medical Sciences, Hubei Key Laboratory of Embryonic Stem Cell Research Hubei University of Medicine Shiyan PR China State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of Chinese Academy of Agricultural Sciences, Harbin, China School of Biomedical Sciences, The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, The Chinese University of Hong Kong, Shatin, Hong Kong Department of Colorectal and Anal Surgery, Xinhua Hospital Shanghai Jiao Tong University School of Medicine Shanghai China; Shanghai Colorectal Cancer Research Center Shanghai China Blood Diseases Institute, Xuzhou Medical University, Xuzhou, China Qingdao Starr Heart Hospital, Qingdao 266011 Department of Nephrology, Guangzhou Red Cross Hospital, Jinan University, Guangzhou City, China School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Target, Nantong University, Nantong 226001, P. R. China Central Laboratory Shanghai Xuhui Central Hospital/Zhongshan‐Xuhui Hospital Fudan University Shanghai People's Republic of China; Shanghai Engineering Research Center of Phase I Clinical Research Quality Consistency Evaluation for Drugs Shanghai People's Republic of China Institute of Soil Science, Chinese Academy of Sciences, Nanjing 210008, China Department of Pharmacology and Neurobiology, Nanjing Medical University, Nanjing 210029, China. ghu@njmu.edu.cn Key Laboratory of Communication and Information Systems, Beijing Municipal Commission of Education, Beijing Jiaotong University 2 , Beijing 100044, China Department of Cardiothoracic Surgery, the First College of Clinical Medical Science, China. Department of Chemistry, and Shanghai Stomatological Hospital, Fudan University, Shanghai 200000, China Department of Endocrine and Metabolic Diseases, Rui-jin Hospital, Shanghai Jiao-tong University School of Medicine, Shanghai Clinical Center For Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai, China. Department of Medical Oncology, The First Affiliated Hospital of Hainan Medical University , Haikou , Hainan 570102 , P.R. China Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences, Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China; School of Graduate Students, University of Science and Technology of China, Hefei 230026, China Department of Laboratory Diagnosis, Changhai Hospital, Second Military Medical University Key Laboratory of Biomedical Polymers of Ministry of Education and Department of Chemistry; Wuhan University; Wuhan 430072 P.R. China NIST Centre for Neutron Research, National Institute of Standards and Technology; Gaithersburg; USA; Department of Chemical and Biomolecular Engineering; Centre for Neutron Science College of Life Science and Technology, Beijing University of Chemical Technology School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, Shandong 250200, China; Institute of Materia Medica, Shandong Academy of Medical Sciences, Key Laboratory for Biotech-Drugs Ministry of Health, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Jinan, Shandong 250062, China School of Psychology Nanjing Normal University Nanjing China Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, NIST Center of Neutron Research, National Institute of Standard and Technology, Gaithersburg, Maryland, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland, and Department of Chemistry, National Taiwan University, Taipei, Taiwan 106 Key Laboratory of Ion Beam Bioengineering; Hefei Institutes of Physical Science; Chinese Academy of Sciences and Anhui Province; Hefei Anhui 230031 P. R. China Department of Rheumatology Zhongshan Hospital Fudan University Shanghai China Center for Reproductive Medicine 900th Hospital of Joint Logistics Support Force of PLA Fuzhou China Sichuan Agricultural University, Ya'an, 625014, China. melody_liuyun_19@126.com Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States Department of Orthopedics, Northern Jiangsu People's Hospital, Clinical Medical College of Yangzhou University Yangzhou 225001, Jiangsu, China. Department of Nephrology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong 510632, P.R. China Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, PR China Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States Department of Geriatrics The First Affiliated Hospital of Nanjing Medical University Nanjing China; Department of Medical Informatics School of Biomedical Engineering and Informatics Nanjing Medical University Nanjing China Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China Department of Chemistry, Indiana University, Bloomington, IN 47405; Cadre Wards of Neurology Medicine Jiangxi Provincial People's Hospital Nanchang China Department of Obstetrics The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University Wuxi China Department of Physics; Dalian University of Technology; Dalian 116024; China Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University Research Division of Clinical Pharmacology First Affiliated Hospital of Nanjing Medical University Nanjing China Department of obstetrics Tianjin Nankai Hospital Tianjin China Department of Oral Implantology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-Sen University, Guangzhou, PR China; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, PR China Department of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing 100081, PR China Hefei National Laboratory for Physical Science at the Microscale Department of Chemistry University of Science and Technology of China Hefei Anhui 230026 P. R. China Australian Institute for Bioengineering and Nanotechnology The University of Queensland St. Lucia QLD 4072 Australia Department of Obstetrics and Gynecology, Fuzhou General Hospital of Nanjing Command, PLA, Fuzhou 350025, China. liuyun95@yahoo.com.cn Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, High Magnetic Field Laboratory, HFIPS, Anhui, Chinese Academy of Science, Hefei 230031, China Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China Beijing National Laboratory for Molecular Sciences and the Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China Radiology Department Minda Hospital of Hubei Minzu University Enshi China Department of Critical Care Medicine, Nanjing Zhongda Hospital, Southeast University, Nanjing 210009, China. Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA; Department of Chemical & Biomolecular Engineering, University of Delaware, Newark, DE, 19716, USA Departments of Respiratory, Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China. yangkun113@sohu.com Institute of Biomedical Sciences Fudan University Shanghai China Department of Critical Care Medicine, Zhongda Hospital, Southeast University, Nanjing 210009, China. School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials Jiangsu Normal University Xuzhou Jiangsu 221116 People's Republic of China Central Laboratory, Shanghai Xuhui Central Hospital and Shanghai Clinical Center Chinese Academy of Science 966 Middle Huaihai Road Shanghai 200031 China Google Health, Google LLC, Mountain View, California Harbin Sport College, Heilongjiang 15000, China. Department of Obstetrics and Gynecology, Beijing Friendship Hospital Affiliated to Capital Medical University, Beijing, China College of Physical Science and Technology, Central China Normal University, Wuhan 430079, China Department of Pediatric Oncology, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China; National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China; Key Laboratory of Cancer Prevention and Therapy, Tianjin 300060, China; Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China School of Life Science, Shenzhen University, Nanhai Ave 3688, Shenzhen 518060, China College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China School of Medicine, Jiangsu University, Zhenjiang 212013, Jiangsu, PR China Department of Endoscopic Center, Jingmen First People's Hospital, Jingmen, Hubei, China. Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, Shanghai, China; Department of Biochemistry and Molecular Biology, Key Laboratory of Molecular Medicine, The Ministry of Education, Fudan University Shanghai Medical College School of Microelectronics, Dalian University of Technology, Dalian 116024, P. R. China Key Laboratory of Microorganism and Genetic Engineering of Shenzhen City, College of Life Science, Shenzhen University, Shenzhen 518060, China. Department of Pharmacy First People's Hospital of Lianyungang City Lianyungang China College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua, Zhejiang 321004, China State Key Laboratory of Luminescence and Applications; Changchun Institute of Optics, Fine Mechanics and Physics; Chinese Academy of Sciences; Changchun 130033; P. R. China NIST Center for Neutron Research, 100 Bureau Drive, Gaithersburg, Maryland, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland, Chemical and Environmental Sciences Laboratory, General Motors Corporation, Warren, Michigan, and ISIS Facility, CCLRC Rutherford Appleton Laboratory, Chilton OX11 0QX, United Kingdom Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116, Jiangsu, PR China Key Laboratory of Biomedical Polymers of the Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, P. R. China Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, People’s Republic of China Department of Pediatric Oncology, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Department of Genetics, School of Basic Medical Sciences Tianjin Medical University Tianjin China Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, Sichuan, People's Republic of China. Hefei National Laboratory for Physical Science at the Microscale, Department of Chemistry University of Science and Technology of China Hefei Anhui 230026 P. R. China Google Health, Palo Alto, California Central Laboratory, Shanghai Xuhui Central Hospital/Zhongshan ‐ Xuhui Hospital Fudan University Shanghai China; Shanghai Engineering Research Center of Phase I Clinical Research & Quality Consistency Evaluation for Drugs Shanghai China Center for Neutron Research; National Institute of Standards and Technology; Gaithersburg; USA State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, International School of Materials Science and Engineering, Wuhan University of Technology, Wuhan 430070, People’s Republic of China School of Information Science and Technology, Qingdao University of Science and Technology, Qingdao 266000, China Research Center of Chinese Herbal Resource Science and Engineering, Key Laboratory of Chinese Medicinal Resource from Lingnan (Guangzhou University of Chinese Medicine), Ministry of Education, Joint Laboratory of National Engineering Research Center for the Pharmaceutics of Traditional Chinese Medicines, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong 510006, China Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai, China Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China Division of Rheumatology the First Affiliated Hospital Xinxiang Medical University Weihui China Guangdong Key Laboratory for Research and Development of Natural Drugs, School of Pharmacy, Guangdong Medical University, Zhanjiang, China; The Marine Biomedical Research Institute of Guangdong, Zhanjiang, China The Seventh Affiliated Hospital, Sun Yat-sen University Pelvic Floor Disorder Center, Obstetrics and Gynecology Department, , Shenzhen , China for the 23andMe Research Team, China Kadoorie Biobank Collaborative Group, and Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium School of Clinical Medicine, Tsinghua University Beijing China Wuhan National Laboratory for Optoelectronics, and School of Optical and Electronic Information, Huazhong University of Science and Technology, Wuhan 430074, China Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Shanghai R&D Centre for Standardization of Chinese Medicines, Shanghai 201210, China Phase I Clinical Trial Unit, Jiangsu Province Hospital and the First Affiliated Hospital with Nanjing Medical University, Nanjing, China Department of Spine and Osteopathic Surgery First Affiliated Hospital of Guangxi Medical University Nanning China; Research Centre for Regenerative Medicine Guangxi Key Laboratory of Regenerative Medicine Guangxi Medical University Nanning China; Division of Regenerative Biology School of Biomedical Sciences University of Western Australia Perth WA Australia Department of Mechanical Engineering, University of Maryland, College Park, MA, 20742, USA State Key Laboratory of Oncogenes and Related Genes, Renji- Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China Department of Spine and Osteopathic Surgery First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China; Division of Regenerative Biology School of Biomedical Sciences University of Western Australia Perth WA Australia; Research Centre for Regenerative Medicine Guangxi Key Laboratory of Regenerative Medicine Guangxi Medical University Nanning Guangxi China Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China Shaanxi Engineering Research Center of Green Low-Carbon Energy Materials and Processes, College of Chemistry and Chemical Engineering, Xi’an Shiyou University, Xi’an 710065, China Department of Neonatology, Luoyang Women and Children's Medical Care Center, Luoyang, Henan, China. liuyunwenrui@yahoo.com.cn Department of Medical Oncology, Cancer Institute/Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. School of Biomedical Sciences, University of Western Australia, Perth, WA 6009, Australia; Department of Orthopaedics, First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China Division of Pharmacoengineering and Molecular Pharmaceutics, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing 210093, China The Key Laboratory for Silviculture and Conservation of the Ministry of Education, Beijing Forestry University, Beijing 100083, China Department of Digestive, The Affiliated People’s Hospital, Jiangsu University, Zhenjiang, Jiangsu, China; School of Medicine, Jiangsu University, Zhenjiang, Jiangsu, China. Department of Radiology Xinqiao Hospital Army Medical University Chongqing 400037 P. R. China Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States; Center for Neutron Science, National Institutes of Standards and Technology, Gaithersburg, Maryland 20899, United States State Key Laboratory of Catalysis, Collaborative Innovation Center of Chemistry for Energy Materials, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Zhongshan Road 457, Dalian 116023, China. State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China; Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou 221116, P. R. China School of Mathematical Sciences, Peking University, Beijing, China State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco‐Environmental Sciences Chinese Academy of Sciences Beijing 100085 China; Key Labora tory of Ion Beam Bioengineering Hefei Institutes of Physical Science Chinese Academy of Sciences and Anhui Province Hefei Anhui 230031 China Department of Pathogenic Biology, School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, China Key Laboratory for Developmental Genes and Human Disease, Ministry of Education, Institute of Life Sciences, Southeast University, Nanjing 210096, China; Co-innovation Center of Neuroregeneration, Nantong University, Nantong 226001, China; Joint Research Institute of Southeast University and Monash University, Suzhou 215123, China Intensive Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China. Fritz-Haber-Institut der Max-Planck-Gesellschaft , Faradayweg 4-6, 14195 Berlin, Germany Key Laboratory of Protein Chemistry and Fish Developmental Biology of the Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha 410081, People's Republic of China Department of Pharmacy, China Pharmaceutical University, Nanjing, PR China Jiangsu Key Laboratory of Green Synthetic for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, Jiangsu 221116, China Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China NIST Center for Neutron Research 2 , Gaithursburg, Maryland 20899, USA; University of Delaware 3 Department of Chemical and Biomolecular Engineering, , Newark, Delaware 19716, USA Department of Chemistry, Indiana University, 800 East Kirkwood Avenue, Bloomington, Indiana 47405, United States 7Arizona Cancer Center, University of Arizona, Tucson, Arizona Neonatal Medical Center Children's Hospital of Nanjing Medical University Nanjing China Phase 1 Clinical Trial Unit The First Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu China Department of Mechanical Engineering, University of Maryland, College Park, Maryland 20742, United States College of Life Sciences, Hunan Normal University, ChangSha 410081, Hunan, People's Republic of China Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, China Department of Anesthesiology, Gulou School of Clinical Medicine, Nanjing Medical University, Nanjing, Jiangsu, China (mainland) Department of Colorectal and Anal Surgery Shanghai Colorectal Cancer Research Center Xinhua Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200092 China University of Delaware 1 Center for Neutron Science, Department of Chemical and Biomolecular Engineering, , 150 Academy St, Newark, Delaware 19716, USA; National Institute of Standards and Technology 3 NIST Center for Neutron Science, , Gaithersburg, Maryland 20899, USA Guizhou Key Laboratory of Anesthesia and Organ Protection, Zunyi Medical College, Zunyi, China; Research Center for Medicine & Biology, Zunyi Medical College, Zunyi, China Guangdong Key Laboratory of Crop Germplasm Resources Preservation and Utilization, Agro-biological Gene Research Center, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, People's Republic of China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, Sun Yat-Sen University, Guangzhou, P.R. China Fudan University Institutes of Biomedical Sciences; Shanghai China; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education); Shanghai Jiao Tong University; Shanghai China Department of General Surgery, Ningbo Zhenhai Longsai Hospital, Ningbo, Zhejiang Province 315200, China Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, China. State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China; Key Laboratory for Tropical Marine Fishery Resource Protection and Utilization of Hainan Province, Hainan Tropical Ocean University, Sanya 570228, China Department of General Surgery, The 4th Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia 014040, P.R. China Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China Georgia Cancer Center Augusta GA; Department of Geriatrics Union Hospital, Tongji Medical College, Huazhong University of Science and Technology China Department of Immunology, Zhongshan School of Medicine, the Secondary Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou 510080, China. Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, and Geosciences Department, State University of New York at Stony Brook, New York 11794-2100 Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia, Queensland 4072, Australia 6Institutes of Biomedical Sciences, Fudan University, Shanghai, P.R. China. School of Finance and Mathematics, Huainan Normal University, Huainan 232038, China Department of Laboratory Diagnosis Changhai Hospital Second Military Medical University 168 Changhai Road Shanghai 200433 China Department of Pathophysiology, School of Medicine, Shenzhen University, Shenzhen, China; Division of Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery; Eshelman School of Pharmacy; University of North Carolina at Chapel Hill; Chapel Hill; USA School of Biomedical Sciences, The University of Western Australia, Perth, WA, Australia; Department of Orthopaedics, First Affiliated Hospital of Guangxi Medical University, Nanning, China Neurodegenerative Disease Research Program, Burnham Institute for Medical Research, La Jolla, CA 92037; Department of Emergency Department of Intensive Care Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China International Center for Planetary Science, College of Earth Sciences, Chengdu University of Technology, Chengdu 610059, China School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou 450046, P. R. China National Key Laboratory of Veterinary Public Health Security, College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Pathogen Biology & Department of Pharmacology School of Basic Medical Sciences Tianjin Medical University Tianjin China Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University , Nanjing, Jiangsu, 210009, China; Department of Information, The First Affiliated Hospital, Nanjing Medical University , Nanjing, Jiangsu, 210029, China Department of Chemistry, Institutes of Biomedical Sciences, and Department of Macromolecular Science, Fudan University, Shanghai 200433, People's Republic of China, and Laboratoire d'Electrochimie Physique et Analytique, Ecole Polytechnique Federale de Lausanne, CH-1015 Lausanne, Switzerland Clinical Research Center, Shanghai Xuhui Central Hospital, Shanghai, China School of Pharmacy and Jiangsu Province Key Laboratory for Inflammation and Molecular Drug Targets, Nantong University, Nantong 226001, People’s Republic of China Advanced Photonics Center, Southeast University, Nanjing 210096, China Department of Laboratory Diagnostics, Changhai Hospital, Navy Medical University, Shanghai, China Hepatology Surgery Zhongshan Hospital, Xiamen University Xiamen Fujian Province People's Republic of China China-EU Institute for Clean and Renewable Energy, Huazhong University of Science and Technology, Wuhan 430074, China; Center for Fuel Cell Innovation, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China University of Delaware 3 Department of Chemical and Biomolecular Engineering, , Newark, Delaware 19716, USA; National Institute of Standards and Technology 4 Center for Neutron Research, , Gaithersburg, Maryland 20899, USA Department of Gynecology, Tang‑Shan Central Hospital, Tangshan, Hebei 063000, P.R. China Department of Physiology, Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100000, PR China Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, PR China; Shanghai R&D Centre for Standardization of Chinese Medicines, Shanghai, 201210, PR China Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University, Zhanjiang, 524023, China Department of Medical Informatics School of Biomedical Engineering and Informatics Nanjing Medical University Nanjing Jiangsu China Department of Cardiothoracic Surgery, China Three Gorges University, Yichang, Hubei, China. School of Pharmacy, Nantong University, Nantong 226001, P. R. China Department of Neuroscience, UT Southwestern Medical Center, Dallas, TX 75235, USA Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology the NMPA and State Key Laboratory of Respiratory Disease School of Pharmaceutical Sciences and the Fifth Affiliated Hospital Guangzhou Medical University Guangzhou 511436 China; Guangdong Provincial Institute of Biological Products and Materia Medica Guangzhou China From the Department of Biopharmaceutical Sciences (C.M., Y. Li, J.M., Y. Liu, Q.L., S.N., L.Z., Z.P., D.Z.), College of Pharmacy, Harbin Medical University, Nangang District, Harbin, Heilongjiang, People's Republic of China; Bio-pharmaceutical Key Laboratory of Heilongjiang Province (D.Z.), Harbin, People's Republic of China; Department of Pharmacology (Z.S.), Harbin Medical University-Daqing, Daqing, Heilongjiang Province, People's Republic of China. Department of Spine and Bone Diseases, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China School of Chemical Engineering Beijing Technology and Business University Fucheng Road 100037 Beijing China School of Biomedical Sciences (L.C., J.L., Y.L., C.H.K.C.), The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China; Department of Chemistry; Indiana University; Bloomington; USA Cavendish Laboratory University of Cambridge JJ Thomson Avenue Cambridge CB3 0HE UK Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States; Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States Department of Cardiovascular Surgery, Ruijin Hospital, Shanghai, People’s Republic of China Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China. Medical Department, Shanghai Roche Pharmaceuticals Ltd, Shanghai 201203, China Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, United States; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, United States Department of Diving Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, 200433, P. R. China; Department of Neurosurgery, Loma Linda University, Loma Linda, California 92350; and Divers Alert Network—an associate of Duke University Health System, Durham, North Carolina 27705 Jinling Hospital, Medical School of Nanjing University, Nanjing, China Chemistry and Materials Science, Jiangsu Normal University, Xuzhou, Jiangsu 221116, P. R. China Center for Neutron Research; National Institute of Standards and Technology; Gaithersburg, USA; Department of Chemical and Biomolecular Engineering; University of Delaware Experiment Center of Teaching & Learning; Shanghai University of Traditional Chinese Medicine; Shanghai; China; School of Pharmacy Key Laboratory of Molecular Biophysics, Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, People's Republic of China Department of Gynecology and Obstetrics, Fuzhou General Hospital, Fuzhou, Fujian, 350025 PR China. liuyun95@sina.com College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Spine Osteopathy Surgery First Affiliated Hospital Guangxi Medical University Nanning People's Republic of China Department of Chemistry; Liaocheng University; Liaocheng 252059; China Department of Spine and Bone Diseases, the First Affiliated Hospital of Guangxi Medical University, Nanning City, China; Research Centre of Regenerative Medicine, Guangxi Medical University, Nanning City, China Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, United States Department of Anesthesiology, The Affiliated Zhangjiagang Hospital of Soochow University, Suzhou, China Department of Gynecology & Obstetrics, Beijing Friendship Hospital, Capital Medical University, Beijing, China Beijing Institute of Radiation Medicine Beijing China College of Life Science, Southwest Forestry University, Kunming 650224, PR China Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue, Wuhan 430030, China Shandong Provincial Key Laboratory of Plant Stress Research, College of Life Science, Shandong Normal University, Shandong 250014, PR China Respiratory Departments, Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710004, China. Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, PR China Department of Pharmacy, China Pharmaceutical University, Nanjing 211198, PR China Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China Beijing Key Laboratory of Bioprocess, The Biorefinery Research and Engineering Center of the Ministry of Education of China, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, China Materials Characterization Core Facility, Centre for Advanced Materials Research (CAMaR), University of Ottawa, Ottawa, Canada Stratingh Institute for Chemistry University of Groningen The Netherlands National Institute of Standards and Technology 3 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA and Department of Chemical Engineering, , Newark, Delaware 19716, USA; University of Delaware 3 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA and Department of Chemical Engineering, , Newark, Delaware 19716, USA Institute of Medical Informatics and Management, Nanjing Medical University, Nanjing, Jiangsu, 210029, China; Department of Information, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, 210029, China Department of Urology, The Second Xiangya Hospital Central South University Changsha Hunan 410011 China; Uro‐Oncology Institute of Central South University The Second Xiangya Hospital, Central South University Changsha Hunan 410011 China School of Mathematical Sciences and Center for Statistical Science, Peking University, Beijing, P. R. China Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for Cancer Tianjin China; Key Laboratory of Cancer Prevention and Therapy Tianjin China; Tianjin's Clinical Research Center for Cancer Tianjin China Department of Endocrine and Metabolic Diseases Shanghai Clinical Center for Endocrine and Metabolic Diseases Shanghai Institute of Endocrine and Metabolic Diseases Ruijin Hospital Shanghai Jiaotong University School of Medicine Shanghai China Key Laboratory of Soil Environment and Pollution Remediation Institute of Soil Science Chinese Academy of Sciences 210008 Nanjing P. R. China Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy and Joint Research Institution of Altitude Health and National Clinical Research Center for Geriatrics,West China Hospital Sichuan University Sichuan Chengdu China 1Key Laboratory of Breast Cancer Prevention and Therapy, Laboratory of Cancer Cell Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China. Department of General Surgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China From the College of Life Sciences, Hunan Normal University, Changsha, Hunan, China; the Changchun Institute of Optics, Fine Mechanics and Physics Key Laboratory of Sustainable Exploitation of Oceanic Fisheries Resources Ministry of Education College of Marine Sciences Shanghai Ocean University Shanghai 201306 China Department of Gynaecology and Obstetrics, Tianjin Nankai Hospital, Tianjin, China Key Laboratory of Communication and Information Systems, Beijing Municipal Commission of Education, Beijing Jiaotong University, Beijing 100044, China Department of Agronomy & James D. Watson Institute of Genome Sciences, Zhejiang University, Hangzhou 310058, China Key Laboratory of the Ministry of Education for Modern Metallurgy Technology, College of Metallurgy and Energy, North China University of Science and Technology, Tangshan 063210, China Department of Veterinary Surgery, College of Veterinary Medicine, Northeast Agricultural University, Harbin, Heilongjiang 150030, P.R. China Department of Forensic Biology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, People's Republic of China. Department of Ultrasonography, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China. School of Mechanical Engineering, Purdue University, West Lafayette, IN 47907, USA Department of Veterinary Clinic, College of Veterinary Medicine, Northeast Agricultural University, Harbin , Heilongjiang 150000 , PR China Department of Endocrinology, Affiliated Hospital of Xiangnan University, Chenzhou, Hunan 423000, P.R. China Beijing National Laboratory for Molecular Sciences (BNLMS) Key Laboratory of Green Printing, Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China; University of Chinese Academy of Science Beijing 100049 P. R. China State Key Laboratory of Biotherapy and Cancer Center, National Clinical Research Center for Geriatrics, Joint Research Institution of Altitude Health, West China Hospital of Sichuan University, Chengdu 610041, Sichuan,China Department of Chemistry, University of Minnesota, 207 Pleasant St. SE, Minneapolis, Minnesota 55455-0431, and Kimika Fakultatea, Euskal Herriko Unibertsitatea, P. K. 1072, 20080 Donostia, Euskadi, Spain Department of Materials Science and Engineering, State University of New York at Stony Brook, Stony Brook, NY 11794-2275, USA. Department of Gastroenterology, Zhongshan Hospital, Fudan University, Xuhui, Shanghai 200032, China State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Beijing Key Laboratory of Ornamental Plants Germplasm Innovation & Molecular Breeding, China National Engineering Research Center for Floriculture, College of Landscape Architecture, Beijing Forestry University, Beijing 100083, China a School of Life & Technology, Xi'an Jiaotong University, Xi'an 710049, China; Department of Chemistry, School of Science, Xi'an Jiaotong University, Xi'an 710049, China Research Division of Clinical Pharmacology First Affiliated Hospital of Nanjing Medical University Nanjing P. R. China National Institute of Standards and Technology 4 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA; University of Delaware 5 Department of Chemical Engineering, , Newark, Delaware 19716, USA University of Delaware 9 Department of Chemical Engineering, , Newark, Delaware 19716, USA; National Institute of Standards and Technology 10 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA Department of Gastroenterology, Peking University People’s Hospital, Beijing, China; Clinical Center of Immune-Mediated Digestive Diseases, Peking University People’s Hospital, Beijing, China Research School of Chemistry, Australian National University, Canberra, 2601, Australia Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China (mainland) Department of Pediatrics, First Affiliated Hospital of Nanchang University, Nanchang 330006, China. wxh0709@163.com. Helmholtz Institute for Pharmaceutical Research Saarland (HIPS)─Helmholtz Centre for Infection Research (HZI), Campus E 8.1, 66123 Saarbrücken, Germany; Department of Pharmacy, Saarland University, 66123 Saarbrücken, Germany School of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Erasmus School of Health Policy and Management Erasmus University Rotterdam Rotterdam the Netherlands Department of Chemistry, Institute of Biomedical Sciences and State Key Lab of Molecular Engineering of Polymers, Fudan University, 220 HanDan Road, Shanghai 200433, China Institute of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116, Jiangsu, P. R. China Department of Chemotherapy, Nanjing Medical University Affiliated Cancer Hospital, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing 210009, China University of Michigan School of Public Health, Ann Arbor, Michigan, USA Department of Ultrasonic Medicine, The Third People's Hospital of Qingdao, Qingdao, Shandong 266041, P.R. China Dalian Institute of Chemical Physics; Chinese Academy of Sciences; Dalian 116023; P. R. China; University of Chinese Academy of Sciences Institute of Toxicology, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China Department of Hepatobiliary Surgery, Zhongshan Hospital, Xiamen University, Xiamen 361001, China Department of Clinical Laboratory, Nanjing Maternity and Child Health Care Hospital, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China Department of Nephrology, The 97th Hospital of PLA Affiliated with Bengbu Medical College, Xuzhou, China; Department of General Surgery, The Sixth Medical Center of PLA General Hospital of Beijing, Beijing, China Department of Pharmacy The First Affiliated Hospital with Nanjing Medical University Nanjing People's Republic of China Department of Rheumatology, Zhongshan Hospital, Fudan University , Shanghai, PR China Department of Nuclear Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 Google AI Healthcare, Google LLC, Mountain View, CA, USA Contribution from the Department of Chemistry, University of California, Berkeley, California 94720, Chemical and Environmental Sciences Laboratory, General Motors Corporation, Warren, Michigan 48090, College of Engineering, Purdue University, West Lafayette, Indiana 47907, Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742, and Indiana University... Key Laboratory for Forest Resources Conservation and Utilization in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, Kunming 650224, People’s Republic of China Chemical Biology; Stratingh Institute for Chemistry; University of Groningen; 9747AG Groningen; The Netherlands Department of Biochemistry and Molecular Biology and The Walther Oncology Center, Indiana University School of Medicine, Indianapolis, Indiana 46202 Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine Shanghai China Cancer Center, Research Institute of Surgery, Daping Hospital, The Third Military Medical University, Chongqing 400042, P.R. China State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), School of Life Sciences, Sun Yat-Sen University, Guangzhou, China Cadre Wards of Neurology Medicine, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi 330006, China. Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization Nanjing University of Chinese Medicine Nanjing China; Jiangsu Key Laboratory for High Technology Research of TCM Formulae Nanjing University of Chinese Medicine Nanjing China Guizhou Provincial College-based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical University, Zunyi 563000, China. Department of Gastroenterology, Zhongshan Hospital, Fudan University, Shanghai 200032, China Institute of Basic Medicine and Forensic Medicine North Sichuan Medical College Nanchong China Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical University, Zhanjiang 524023, P. R. China School of Medicine Jiangsu University Jiangsu China Department of Biopharmaceutical Sciences College of Pharmacy Harbin Medical University‐Daqing Daqing Heilongjiang China Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education; Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, Shanghai, P.R. China Beijing National Laboratory for Molecular Science (BNLMS) Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China Center of Nephrology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China. iooi0302@163.com CAS Key Laboratory of Marine Ecology & Environmental Sciences, Institute of Oceanology Chinese Academy of Sciences Qingdao 266071 China; Laboratory for Marine Ecology & Environmental Science Qingdao National Laboratory for Marine Science and Technology Qingdao 266200 China Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi Province, PR China Department of Cancer Center, Daping Hospital Army Medical University Chongqing China Department of Materials Science and Engineering Massachusetts Institute of Technology 77 Massachusetts Avenue Cambridge MA 02139 USA Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry, Wuhan University, Wuhan 430072, P. R. China South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006, China NIST Center for Neutron Research, National Institute of Standards and Technology, 100 Bureau Drive, MS 6100, Gaithersburg, Maryland 20899-6100, United States; Department of Chemical Engineering, University of Delaware, Newark, Delaware 19716, United States Institut Laue-Langevin, B.P. 156, F-38042 Grenoble CEDEX 9, France, The Center for Nanophase Materials Sciences, Neutron Scattering Science Division, Spallation Neutron Source, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831, and The NIST Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-6100, Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education, 200032 Shanghai, People’s Republic of China;; Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, 200032 Shanghai, People’s Republic of China; Massachusetts Institute of Technology Nuclear Science and Engineering Department, , Cambridge, Massachusetts 02139 Department of Pediatrics, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, PR China Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27514, USA School of Biomedical Sciences, The University of Western Australia, Perth, WA, Australia; Department of Orthopaedics, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China Guangdong Provincial Key Laboratory for Plant Epigenetics, Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen 518060, China Department of Chemistry, University of New Mexico, Albuquerque, New Mexico 87131, and Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455 Department of Urinary Surgery Renmin Hospital, Hubei University of Medicine Shiyan Hubei People's Republic of China MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhongshan Hospital, Fudan University, Shanghai, China, 200032 The Transplantation Center of The Third Xiangya Hospital, Central South University, Changsha, Hunan, China (mainland) Department of Neurology the First Affiliated Hospital of Nanjing Medical University Nanjing China; Jiangsu Province, Key Laboratory of Neurodegeneration Nanjing Medical University Nanjing China Department of Orthopedics, The First Affiliated Hospital of Guangxi Medical University, Nanning, China State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Drug Screening, China Pharmaceutical University , Nanjing 210009, China State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, Fujian 361102, China. Xi’an University of Technology Key Laboratory for Forest Resources Conservation and Utilisation in the Southwest Mountains of China, Ministry of Education, Southwest Forestry University, 650224 Kunming, Yunnan, People's Republic of China; School of Light Industry and Food Engineering, Southwest Forestry University, 650224 Kunming, People's Republic of China State Key Laboratory of Bioorganic and Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China Department of Diving Medicine, Faculty of Naval Medicine, Changhai Hospital, Second Military Medical University, Shanghai, P.R. China. Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China. Department of Prosthodontics Peking University School and Hospital of Stomatology Beijing China; Center for Oral Functional Diagnosis, Treatment and Research Peking University School and Hospital of Stomatology Beijing China The Ministry of Education Key Laboratory of Metabolism and Molecular Medicine Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Fudan University Shanghai China Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China NCNR, National Institute of Standards and Technology, Gaithersburg, Maryland, United States; Department of Chemical Engineering, University of Delaware, Newark, Deleware, United States College of Science, Shaanxi University of Science and Technology, Xi’an, 710021, China School of Biomedical Sciences (L.C., J.L., Y.L., C.H.K.C.), The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Department of Radiology; Xinqiao Hospital; Army Medical University; Chongqing 400037; PR China Echo Laboratory, Department of Ultrasound Imaging, Renmin Hospital of Wuhan University Wuhan, China. School of Civil Engineering, Beijing Jiaotong University, Beijing 100044, China Department of Radiology Xinqiao Hospital Army Medical University Chongqing 400037 China National Institute of Standards and Technology 4 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA and Department of Chemical Engineering, , Newark, Delaware 19716, USA; University of Delaware 4 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA and Department of Chemical Engineering, , Newark, Delaware 19716, USA NIST Center for Neutron Research, National Institute of Standards and Technology, Maryland, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland, and Division of Engineering and Applied Science, California Institute of Technology, Pasadena, California Department of Otolaryngology Head and Neck Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China; Department of Orthopaedics, The First Affiliated Hospital of Guangxi Medical University Department of Colorectal and Anal Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China School of Physics; Dalian University of Technology; Dalian 116024; China Department of Gerontology First Affiliated Hospital of Nanjing Medical University 210029 Nanjing China Department of Geriatrics The First Affiliated Hospital with Nanjing Medical University Nanjing Jiangsu 210029 China Australian Institute for Bioengineering and Nanotechnology The University of Queensland St. Lucia Queensland 4072 Australia Google Health (G.E.D., Y.L., D.T., S.S.), Stanford Health Care and Palo Alto Veterans Affairs (J.J.R.), California, California, USA Institute of Botany, The Chinese Academy of Sciences, Beijing 100093, P. R. China and Institute of Genetics and Developmental Biology, The Chinese Academy of Sciences, Beijing 100080, P. R. China University of Delaware 7 Department of Chemical Engineering, , Newark, Delaware 19716, USA; National Institute of Standards and Technology 8 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA College of Chemistry and Chemical Engineering Hexi University Key Laboratory of Hexi Corridor Resources Utilization of Gansu Zhangye 734000 P.R. China Department of Geratology the First Affiliated Hospital Nanjing Medical University Nanjing 210029 China Department of Spinal Bone Disease, The First Affiliated Hospital of Guangxi Medical University, Nanning, China Departments of aNeuroscience and School of Microelectronics, Dalian University of Technology, Dalian, PR China 116024 Shanghai Institute of Endocrine and Metabolic Diseases, Shanghai Clinical Center for Endocrine and Metabolic Diseases, Department of Endocrinology, Ruijin Hospital, Shanghai Jiaotong University Medical School, 200025, Shanghai, P.R. China Department of Pathophysiology and Key Laboratory of Proteomics of Guangdong Province, Southern Medical University, Guangzhou, China. sysliuyun@126.com 1School of Biomedical Sciences, The Chinese University of Hong Kong-Shandong University Joint Laboratory on Reproductive Genetics, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China Key Laboratory of Ion Beam Bioengineering, Hefei Institutes of Physical Science, Chinese Academy of Sciences and Anhui Province, Hefei, Anhui 230031, P. R. China Department of Anesthesiology Peking University Hospital of Stomatology Beijing China Key Laboratory for Feed Biotechnology of the Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China; College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing, People's Republic of China Key Laboratory of Bio-inspired Smart Interfacial Science and Technology of Ministry of Education, School of Chemistry, Beihang University, Beijing 100191, P. R. China; Key Laboratory of Bio-inspired Materials and Interfacial Science, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China School of Life Science, Key Laboratory of Eco-Environment of Three Gorges Reservoir Region of Ministry of Education, Southwest China Normal University, Chongqing 400715, China. liuyun19970205@sina.com School of Biomedical Engineering and Informatics, Department of Medical Informatics, Nanjing Medical University, Jiangsu, China Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St Lucia, QLD 4072, Australia Center for Structural Biology, Vlaams Instituut voor Biotechnologie , Brussels , Belgium; Structural Biology Brussels, Department of Bioengineering Sciences, Vrije Universiteit Brussel , Brussels , Belgium Department of Pharmacy, The First People’s Hospital of Lianyungang, Lianyungang, PR China; The Seventh Affiliated Hospital, Sun Yat-sen University , Guangdong , China Department of Pharmacy, The First People's Hospital of Lianyungang, Lianyungang, Jiangsu 222061, P.R. China Department of Chemistry and ‡Center for Catalysis Research and Innovation, University of Ottawa, Ottawa ON, Canada K1N 6N5 School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China. School of Biomedical Sciences Core Laboratory, Shenzhen Research Institute, The Chinese University of Hong Kong, Shenzhen, 518057, China. Department of Geratology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China Qingdao University of Science and Technology, Qingdao, China Beijing Key Laboratory of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology Beijing 100029, China. Guizhou Provincial College-Based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical College, Zunyi, Guizhou 563003, China Department of Colorectal Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine , Shanghai , China Research Center for Medicine and Biology, Zunyi Medical University, Zunyi, Guizhou 563003, P.R. China Key Laboratory of Advanced Drug Delivery Systems of Zhejiang Province College of Pharmaceutical Sciences Zhejiang University 310058 Hangzhou China; Jinhua Institute of Zhejiang University 321299 Jinhua China Department of Infection Disease, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China State Key Laboratory of Catalysis, CAS Center for Excellence in Nanoscience, iChEM, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China Fuyang Third People’s Hospital, People’s Republic of China Department of Colorectal Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China; Shanghai Colorectal Cancer Research Center, Shanghai 200092, China College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China Shanghai Clinical Center for Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Department of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, P.R. China NIST Center for Neutron Research, Gaithersburg, Maryland 20899-6100; Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742 Heilongjiang Key Laboratory of Experimental Animals and Comparative Medicine, College of Veterinary Medicine Northeast Agricultural University Harbin China Center for Neutron Research; National Institute of Standards and Technology; Gaithersburg; USA; Chemical & Biomolecular Engineering Department State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals, and the Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China;; School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China; and Research School of Chemistry, Australian National University, Science Road, Canberra, ACT 0200, Australia Center for Oral and Jaw Functional Diagnosis, Treatment and Research Department of Prosthodontics Peking University School and Hospital of Stomatology & National Engineering Laboratory for Digital and Material Technology of Stomatology & Beijing Key Laboratory of Digital Stomatology Beijing China Institute for Medical Engineering and Sciences, Massachusetts Institute of Technology and Harvard‐MIT Division of Health Sciences and Technology, Cambridge, MA Department of Pharmacy The First Affiliated Hospital with Nanjing Medical University Nanjing China Guangdong Provincial Key Laboratory of Molecular Target and Clinical Pharmacology, School of Pharmaceutical Sciences and The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong 511436, P.R. China Department of Medical Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University Affiliated Cancer Hospital, Nanjing, Jiangsu, China (mainland) Key Laboratory of Biorheological Science and Technology; Ministry of Education; College of Bioengineering; Chongqing University; Chongqing 400044, PR China Department of Gynaecology and Obstetrics, Bao’an Maternal and Child Health Hospital, Shenzhen, Guangdong, China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory of Improved Variety Reproduction in Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China Department of Pathology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuang 646000, P.R. China Department of Obstetrics & Gynecology Beijing Friendship Hospital Affiliated to Capital Medical University Beijing China 1 Department of Bioinformatics, George Mason University, Fairfax, VA, 2Department of Biomolecular Engineering, University of California, Santa Cruz, CA and 3Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, 3400 N. Charles St., Baltimore, MD, USA Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences; Institutes of Biomedical Sciences, Fudan University, 200031 Shanghai, PR China Division of Pharmacoengineering and Molecular Pharmaceutics and Center for Nanotechnology in Drug Delivery, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States Department of Oral Implantology, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, P.R. China The Centre for Population Neuroscience and Stratified Medicine and SGDP Centre, Institute of Psychiatry, King’s College London (Tay, Macare, Ruggeri, Jia, Chu, Biondo, Ing, Quinlan, Desrivières, Barker, Schumann); the Department of Biochemistry and Molecular Biology, MOE Key Laboratory of Metabolism and Molecular Medicine, School of Basic Medical Sciences, Fudan University, Shanghai, China (Liu); the Institute of Science and Technology of Brain-Inspired Intelligence, Fudan University, Shanghai, China ... Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-Constructed by the Province and Ministry, Guangxi Medical University, Nanning 530021, China; Department of Spinal Bone Disease, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China Key Laboratory of Green Chemistry & Technology Ministry of Education College of Chemistry Sichuan University Chengdu 610064 China Department of Imaging, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, Jiangxi, China. Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China. College of Communications Engineering, Jilin University, Changchun, China. Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China; CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory for Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University , Nanjing, Jiangsu, China; Institute of Medical Informatics and Management, Nanjing Medical University , Nanjing, Jiangsu, China; Department of Information, The First Affiliated Hospital, Nanjing Medical University , Nanjing, Jiangsu, China Central Laboratory Shanghai Xuhui Central Hospital/Zhongshan‐Xuhui Hospital Fudan University Shanghai 200031 China Jiangsu Key Laboratory of Green Synthetic for Functional Materials and School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou 221116, Jiangsu, P. R. China Department of Obstetrics and Gynecology Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science Xiangyang Hubei China National Institute of Standards and Technology 1 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA; University of Delaware 2 Department of Chemical Engineering, , Newark, Delaware 19716, USA Huazhong Agricultural University, China Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, School of Pharmaceutical Sciences, Chongqing University, 55 South Daxuecheng Road, Chongqing 401331, P. R. China Institute of Medical Informatics and Management Nanjing Medical University Nanjing China; Department of Geriatrics Endocrinology The First Affiliated Hospital of Nanjing Medical University and Jiangsu Province Hospital Nanjing China School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, P. R. China Department of Radiology, Xinqiao Hospital, Army Medical University, Chongqing 400037, P. R. China Shanghai Xuhui Central Hospital; Shanghai China Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, People’s Republic of China Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Chinese Academy of Sciences; Anhui Province Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Anhui 230031, P. R. China School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, Jiangsu, PR China Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China. School of Materials Science and Engineering, and State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan 430070, People’s Republic of China Key Laboratory of Protein Chemistry and Fish Developmental Biology of Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha, 410081, Hunan, China; Health Technology Cadre Training, Jingling Hospital, Nanjing, China Department of Gastroenterology, First Affiliated Hospital, Army Medical University, Chongqing, China. Department of Polymer Science & Engineering and Key Laboratory of High Performance Polymer Materials & Technology of MOE, School of Chemistry & Chemical Engineering, Nanjing University, Nanjing 210093, China Department of Ultrasound Imaging, The First College of Clinical Medical Science, China Three Gorges University, Yichang, China; Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, China Three Gorges University, Yichang, China; Echo Laboratory, Department of Ultrasound Imaging, Renmin Hospital of Wuhan University, Wuhan, China School of Acupuncture and Moxibustion, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, China. Department of Radiation Oncology, Anhui Provincial Cancer Hospital The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China Hefei China Key Laboratory for Thin Film and Microfabrication of Ministry of Education; Research Institute of Micro/Nano Science and Technology; Shanghai Jiao Tong University; Shanghai 200240, P. R. China Department of Pediatrics, Liaocheng People's Hospital, Liaocheng, Shandong, China Department of Environmental Science, East China Normal University, Shanghai 200062, China. Chongqing Key Laboratory of Green Synthesis and Applications; and Chongqing Key Laboratory of Inorganic Functional Materials; College of Chemistry; Chongqing Normal University; Chongqing 401331 Department of Nursing The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital Jinan Shandong China School of Pharmaceutical Sciences and The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, People's Republic of China University of Delaware 1 Center for Neutron Science, Department of Chemical Engineering, , Newark, Delaware 19716, USA; National Institute of Standards and Technology 3 The NIST Center for Neutron Research, , Gaithersburg, Maryland 20899-6100, USA Division of Plastic and Reconstructive Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, USA Department of Chemistry University of Washington Seattle WA 98195 USA Department of Gerontology, the First Affiliated Hospital (Y.L., R.Z., J.X., Y.S.), Nanjing Medical University, Nanjing 210029, China Department of Medical Oncology, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research, Nanjing Medical University Affiliated Cancer Hospital, Nanjing 210009, China Department of Medical Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100021 P. R. China Key Laboratory of Protein Chemistry and Developmental Biology of Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha, Hunan, 410081, China. LANSCE-12 and EES-6, Los Alamos National Laboratory, Los Alamos, New Mexico 87545, NIST Center for Neutron Research, Gaithersburg, Maryland 20899, Department of Materials Science and Engineering, University of Maryland, College Park, Maryland 20742, Department of Natural Sciences, New Mexico Highlands University, Las Vegas, New Mexico 87701, and Department of Chemistry & Biochemistry, Miami University, Oxford, Ohio 45056 Google Health, Google LLC, Palo Alto, California Department of Medicinal Chemistry, School of Pharmaceutical Sciences,Guangzhou Medical University, Guangzhou 511436, China School of Pharmacy Shanghai Jiao Tong University Shanghai P. R. China Department of Colorectal and Anal Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, PR China Massachusetts Institute of Technology Department of Nuclear Science and Engineering, , Cambridge, Massachusetts 02139 Department of Nephrology, Guangzhou Red Cross Hospital of Jinan University, Guangdong Province, P.R. China; Guangzhou Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, Guangdong Province, P.R. China for the EXIT-SEP Investigators School of Biomedical Sciences (Y.L., Y.Z., C.H.K.C.), The Chinese University of Hong Kong, Hong Kong, China; School of Biomedical Sciences Core Laboratory (Y.L., C.H.K.C.), The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen 518057, China Department of Colorectal Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Colorectal Cancer Research Center, Shanghai, China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, Center for Soft Matter Science and Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China Obstetrical Department, Xiangyang Central Hospital, Xiangyang City, China Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States From the Department of Biopharmaceutical Sciences, College of Pharmacy (J.L., J.R., Y.L., Y.Z., Q.Z., D.Z.), Harbin Medical University-Daqing, Daqing, Heilongjiang, China; Biopharmaceutical Key Laboratory of Heilongjiang Province (D.Z.), Harbin, China; and Department of Pharmacology, Harbin Medical University-Daqing, Daqing, China (Y.C.). Otorhinolaryngology Head and Neck Surgery, Beijing Friendship Hospital Capital Medical University Xicheng District Beijing China State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China Cadre Wards of Neurology Medicine Zhongyuan Critical Metals Laboratory School of Chemical Engineering Zhengzhou University Zhengzhou 450052 China State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, PR China Phase 1 Clinical Trial Unit the First Affiliated Hospital with Nanjing Medical University Nanjing China Shicheng People's Hospital, Jiangxi , China. Guizhou Provincial College‑based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines, Zunyi Medical University, Zunyi, Guizhou 563000, P.R. China Clinical Nursing Teaching and Research Section, The Second Xiangya Hospital, Central South University, Changsha, Hunan Province, China Department of Infectious Diseases The First Affiliated Hospital of Nanjing Medical University Nanjing China Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin, China Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Avenue, Jianghan District, Wuhan 430022, China Center for Neutron Research, National Institute of Standards and Technology, Gaithersburg, Maryland 20899-6100, United States; Department of Chemical Engineering, University of Delaware, Newark, Delaware 19716, United States Department of Neuroscience, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75235-9111, USA. Department of Laboratory Diagnosis Changhai Hospital Second Military Medical University Shanghai China State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Department of Chemistry University of Science & Technology of China Hefei Anhui 230026 P. R. China Department of Spinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China Department of Gastroenterology, Peking University First Hospital, Beijing, China Department of Geriatric Endocrinology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, P.R. China State Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Provincial Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China Division of Spinal Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China (mainland) School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou Jiangsu 221116, PR China College of Life Sciences, Key Laboratory of Microorganism and Genetic Engineering of Shenzhen University, Shenzhen 518060, China. sunshine@szu.edu.cn Advanced Photonics Center, School of Electronic Science and Engineering, Southeast University, Nanjing 210096, China Advanced Photonics Center Southeast University Nanjing 210096 China Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Department of Medical Informatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, China Department of Ophthalmology, Heilongjiang Eye Disease Prevention Institute Haerbin 150001, China. Division of Energy Storage Dalian Institute of Chemical Physics Chinese Academy of Sciences Dalian 116023 China; University of Chinese Academy of Sciences Beijing 100049 China Department of Stomatology, The Second Hospital of Jilin University, Changchun 130041, P. R. China 6Institutes of Biomedical Sciences, Fudan University, Shanghai, PR China. Center for Reproductive Medicine, Dongfang Hospital, Xiamen University , Fuzhou; Center for Reproductive Medicine, Fuzong Clinical College, Fujian Medical University (900th Hospital of the Joint Logistics Force) , Fuzhou, China Advanced Photonics Center; Southeast University; Nanjing 210096; China China Agricultural University State Key Laborary of Agrobiotechnology, Beijing Key Laboratory of Growth and Developmental Regulation for Protected Vegetable Crops, College of Horticulture, , Beijing 100193, China Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, No. 74 Linjiang Rd, Yuzhong District, Chongqing400010, P.R. China **Division of Plastic and Reconstructive Surgery and Key Laboratory of Soft Chemistry and Functional Materials (Ministry of Education of China) Nanjing University of Science and Technology Nanjing P. R. China Department of Obstetrics, Shanghai East Hospital Tongji University School of Medicine Shanghai China Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts NCDs Prevention and Control Department, Liuzhou CDC, Liuzhou, Guangxi, China. Department of Gastroenterology Zhongshan Hospital Fudan University Shanghai China Department of Colorectal and Anal Surgery, Xinhua Hospital School of Medicine, Shanghai Jiaotong University Shanghai China Guangdong Provincial Key Laboratory for Plant Epigenetics, Shenzhen Key Laboratory of Microbial Genetic Engineering, College of Life Sciences and Oceanography, Shenzhen University, Nanhai Ave 3688, Shenzhen, Guangdong 518060, China Department of colorectal surgery, Xinhua Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai - China 2Arizona Cancer Center, College of Medicine, University of Arizona, Tucson, Arizona Department of Clinical Laboratory, Shandong Provincial Hospital affiliated to Shandong First Medical University , Jinan, Shandong , China Department of Neurosurgery, The Second Affiliated Hospital, Chongqing Medical University, Chongqing 400010, China Department of Radiology, Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400010, People’s Republic of China Department of Neurology, Shuguang Hospital, Shanghai University of TCM, 185, Pu-An Road, Shanghai 200021, China Peking University Medical and Health Analytical Center, Peking University Health Sciences Center Beijing 100191 People's Republic of China Department of Geriatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China Department of Mechanical and Civil Engineering, Purdue University Northwest, Westville, IN 46391, USA Department of Spinal Bone Disease, The First Affiliated Hospital of Guangxi Medical University, Nanning, China. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou 221116, China Australian Institute for Bioengineering and Nanotechnology The University of Queensland St Lucia QLD 4072 Australia Department of TCM Dermatology, NO.921 Hospital of the PLA Joint Logistic Support Force, Changsha, China Guangdong Provincial Key Laboratory for Plant Epigenetics Shenzhen Key Laboratory of Microbial Genetic Engineering College of Life Sciences and Oceanography Shenzhen University Shenzhen Guangdong P. R. China Key Laboratory of Horticultural Plant Biology (Ministry of Education), Huazhong Agricultural University, Wuhan, China Department of Physics, Southeast University, Nanjing 211189, China Department of Minimally-invasive Gynecology, Beijing, China. College of Veterinary Medicine Northeast Agricultural University Harbin China; Heilongjiang Key Laboratory for Animal Disease Control and Pharmaceutical Development Harbin China Department of Epidemiology, Brown University School of Public Health, Providence, Rhode Island Department of Laboratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai, People’s Republic of China School of Biomedical Engineering and Informatics Nanjing Medical University Nanjing 211166 China |
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