http://rdf.ncbi.nlm.nih.gov/pubchem/author/MD5_d5a12cec60fce5b29bb96fb34e399a68
Outgoing Links
Predicate | Object |
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family-name | Wang Yang Wang |
name | Yang Wang |
given-name | Yang |
organization-name | University of ChicagoChicago, Illinois Antibody Engineering Laboratory, School of Life Science & Technology, China Pharmaceutical University Munich Center for Integrated Protein Science (CIPSM) at the Department of Microbiology, Ludwig-Maximilians-Universität München, 82152 Martinsried, Germany Beijing Artificial Liver Treatment and Training Center, Beijing Youan Hospital, Capital Medical University, Beijing, China The Third Hospital of Hebei Medical University, Shijiazhuang 050051, China. Department of Clinical Pharmacology, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology, China Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology Dana‐Farber Cancer Institute Boston MA USA; Department of Genetics Harvard Medical School Boston MA USA State Key Laboratory of Applied Organic Chemistry School of Chemistry and Chemical Engineering Lanzhou University Lanzhou 730000 P. R. China Department of Medical Research & Biometrics Center, National Center for Cardiovascular Diseases and Fuwai Hospital, CAMS and PUMC, Beijing 100037, China. Department of Gastroenterology Shanghai 10th People's Hospital School of Medicine Tongji University Shanghai 200072 P. R. China Aix-Marseille Université and CNRS; Centre Interdisciplinaire de Nanoscience de Marseille; Marseille, France; College of Chemistry and Molecular Sciences; Wuhan University Beijing National Laboratory for Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China College of Life Science/Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin of Xinjiang Production and Construction Corps, Tarim University, Alar 843300, PR China Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States From Department of Emergency Medicine (Y.W., W.B.L., Y.W., G.L., J.-J.L., X.W., Y.Y., X.-L.M.) and Center for Translational Medicine, Department of Medicine (X.-L.M.), Thomas Jefferson University, Philadelphia, PA; and Center for Translational Medicine, Temple University, Philadelphia, PA (E.G., W.J.K.). Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200092, P.R. China Department of Orthopedics, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University, Number, 250, Changgang East Road, Haizhu District, Guangzhou, Guangdong Province, China Key Laboratory of Saline-alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, Northeast Forestry University, Haerbin, Heilongjiang, China School of Pharmacy Shenyang Pharmaceutical University Shenyang 110016 China; Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 China Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Key Laboratory for Organic Electronics and Information Displays (KLOEID) & Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China Department of Orthopedics, The Second Hospital of Jilin University, Changchun, Jilin 130000, P.R. China Department of Thoracic Oncology II Peking University Hospital (Beijing Cancer Hospital and Institute) Beijing China Engineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural University, Changchun, Jilin, China Key Laboratory of Synthetic and Biological Colloids; Ministry of Education; School of Chemical and Material Engineering; Jiangnan University; Wuxi 214122 Aquatic Products Quality Inspection Center of Zhejiang Province Hangzhou P. R. China Plastic Surgery Hospital of Chinese Academy of Medical Sciences, Beijing 100041, China. Key Laboratory of Mesoscopic Chemistry of Ministry of Education and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China Department of Civil, Architectural, and Environmental Engineering, Missouri University of Science and Technology, Rolla, Missouri 65409, United States College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China Institute of neuroscience, Department of histology and embryology Wenzhou Medical University Wenzhou Zhejiang P. R. China Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China; The Spinal Tumor Center, Changzheng Hospital, Second Military Medical University, Shanghai, China Sanya Central Hospital (Hainan Third People's Hospital) Sanya China 5State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Tianjin, China. Department of Oncology of 363 Hospital, Cheng Du Department of Ultrasound Shengjing Hospital, China Medical University ShenYang Liaoning China Department of Thoracic Surgery, The First People’s Hospital of Yunnan Province, Kunming, Yunnan, China; Department of Thoracic Surgery, The Affiliated Hospital of Kunming University of Science & Technology, Kunming, Yunnan, China Department of Social Affairs The Second Xiangya Hospital Central South University Changsha China Guangxi Medical University First Affiliated Hospital, 6th Building Shuangyong Road, Nanning, China Department of Urology; The Fifth People's Hospital of Shanghai; Fudan University; Shanghai P.R. China Physical and Computational Sciences Directorate, Pacific Northwest National Laboratory , Richland, WA 99352 , USA State Key Laboratory of Coordination Chemistry, Center for Multimolecular Organic Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, 550004 Guizhou, PR China; School of Pharmacy, Guizhou Medical University, Guiyang, 550004 Guizhou, PR China Department Of Cardiology, Affiliated Haikou Hospital Of Xiangya Medical College, Central South University, Haikou, Hainan Province, China National Joint Local Engineering Laboratory for High-Efficient Preparation of Biopesticide, Zhejiang A&F University, Hangzhou, Zhejiang, China Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu 610041, China College of Plant Protection and Shaanxi Key Laboratory of Molecular Biology for Agriculture, Northwest A&F University, Yangling, Shaanxi 712100, China Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology, School of Engineering Medicine, Beihang University, Beijing, China Shenyang National Laboratory for Materials Science, Institute of Metal Research, Chinese Academy of Sciences (IMR), Shenyang 110016, P.R. China; School of Materials Science and Engineering, University of Science and Technology of China, Hefei 230026, P.R. China Department of Prosthodontics and Center for Oral Function Diagnosis, Treatment and Research, Peking University School and Hospital of Stomatology, Beijing 100081, China. Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education; Key Laboratory of Bio-inspired Energy Materials and Devices; School of Chemistry and Environment; Beihang University; China Department of Entomology, China Agricultural University, Yuanmingyuan Xilu No. 2, College of Plant Protection, CAU, Beijing, China From the *Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia; and Departments of †Nuclear Medicine, ‡Orthopaedic Surgery, and §Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China. Department of Plastic and Reconstructive Surgery, Cell and Matrix Research Institute, Kyungpook National University School of Medicine, Daegu, Korea School of Optoelectronic Engineering Chongqing University of Posts and Telecommunications Chongqing China Department of Neurosurgery, First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi 330006, China. Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China; School of Future Technology, University of Chinese Academy of Sciences, Beijing 100049, P. R. China Guang An Men Hospital, China Academy of Chinese Medical Sciences; Department of Acupuncture and Moxibustion; No.5, Beixiange Street, Xuanwu District Beijing China 100053 Department of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical College, Yangzhou University, Yangzhou, Jiangsu 225001, P.R. China Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan Department of Pathophysiology, Wenzhou Medical College, Zhejiang, China. Amgen, Inc., Thousand Oaks, CA; and School of Pharmacy; Nanjing Medical University; Nanjing P. R. China Center of Growth, Metabolism and Aging Key Laboratory of Bio‐Resource and Eco‐Environment of Ministry of Education College of Life Sciences and State Key Laboratory of Biotherapy Sichuan University Chengdu 610014 China Department of Psychology & Center for Cognition and Brain Studies The Chinese University of Hong Kong Hong Kong SAR China College of Pharmacy Shandong University of Traditional Chinese Medicine Jinan 250355 P. R. China Department of Integrated Traditional Chinese and Western Medicine, Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha, PR China Reproductive Centre, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Guizhou, China Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China College of New Energy, State Key Laboratory of Heavy Oil Processing China University of Petroleum (East China) Qingdao 266580 China; Department of Applied Chemistry, School of Engineering University of Toyama, Gofuku 3190 Toyama 930-8555 Japan Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia College of Animal Science and Technology, Qingdao Agricultural University Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Peking University Third Hospital , Beijing, China Department of Hepatobiliary Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, China College of Chemistry and Molecular Engineering; Center of Computational Chemistry; Zhengzhou University; Zhengzhou; PR China Jinshan College of Fujian Agriculture and Forestry University, Fujian Province, 350001, P. R. China MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, Jinan University, Guangzhou 510632, China Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education and School of Physics and Technology, Wuhan University, Wuhan 430079, China Department of Materials Science and Engineering Stanford University Stanford CA USA School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, United Kingdom, and School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, United Kingdom Department of Otolaryngology, Head & Neck Surgery, Tongji Hospital, School of Medicine Tongji University Shanghai China Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University; Global Health Institute, School of Public Health, Xi’an Jiaotong University Health Science Center, Xi’an, China College of Physics Chongqing University Chongqing 401331 P. R. China 1 National Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing 100193, P. R. China Department of Gynecology, Xinan Gynecological Hospital, Chengdu, Sichuan, China School of Chemistry and Materials Science, University of Science and Technology of China, Hefei, Anhui230026, China College of Pharmacy of Liaoning University, New Drug R&D Key Laboratory of Liaoning Province, Shenyang, P. R. China; Department of Clinical Pharmacy, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College Huazhong University of Science and Technology Wuhan People's Republic of China; Clinical Medical Research Center for Neurodevelopmental Disabilities in Children, Hubei Province People's Republic of China Department of Surgery, Helen Diller Family Comprehensive Cancer Center University of California San Francisco CA USA; Department of Thoracic Surgery Beijing Chao‐Yang Hospital, Capital University of Medical Science Beijing People's Republic of China National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China; Key Laboratory of Animal Antimicrobial Resistance Surveillance, Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China 2Immunomedics, Inc., Morris Plains, New Jersey; and Department of Dermatology Beijing Children’s Hospital Capital Medical University National Center for Children’s Health Beijing China School of Public Health, Peking University, Beijing 100191, China. wangyang.hi@gmail.com Key Laboratory of Photochemical Conversion and Optoelectronic Materials New Cornerstone Science Laboratory Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China; School of Future Technology University of Chinese Academy of Sciences Beijing 100049 P. R. China Department of Pharmaceutics, Guang Xi University of Chinese Medicine, Guangxi 530001, China Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada;; Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China; School of Food Science and Engineering, Yangzhou University, 196 Huayang West Road, Yangzhou, Jiangsu 225127, China Department of Urology, Affiliated Wuxi No.2 Hospital, Nanjing Medical University , Wuxi , China State Key Laboratory of Electronic Thin Film and Integrated Devices University of Electronic Science and Technology of China Chengdu 610054 China Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China Department of Pathology, University of Chicago, Chicago, IL 60637 Department of Integrated Traditional Chinese & Western Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China Department of Physiology, China Medical University (CMU), Shenyang, PR China Department of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, People’s Republic of China Beijing Advanced Innovation Centre for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Chemistry Boston College Chestnut Hill MA 02467 USA Department of General Surgery, Center for Evidence-Based Medicine and Clinical Research, Huaihe Hospital of Henan University, Kaifeng, Henan, China (mainland) Department of Oncology, Panjin Liaoyou Gem Flower Hospital State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing 211166, Jiangsu, P.R. China Neuroscience and Neuroengineering Research Center, Med-X Research Institute and School of Biomedical Engineering Shanghai Jiao Tong University, Shanghai, People’s Republic of China; Department of Neurology, Ruijin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China Department of Dermatology and Venerology, Peking University First Hospital, Beijing 100034, China Department of Medical Microbiology and Immunology, School of Medicine Key Laboratory of Synthetic and Biological Colloids Ministry of Education School of Chemical and Material Engineering Jiangnan University Wuxi 214122 P. R. China Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Department of Radiology, Tianjin Medical University General Hospital, Tianjin Key Laboratory of Functional Imaging, Tianjin 300052, P.R. China Laboratory of Ethnopharmacology Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University 410008 Changsha China Key Laboratory of Biomedical Polymers-Ministry of Education College of Chemistry and Molecular Sciences Wuhan University Wuhan 430072 P. R. China MassBiologics, University of Massachusetts Medical School , Boston, Massachusetts , USA Department of Thoracic Surgery Affiliated Hospital of Guilin Medical University Guilin China Section of Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, Biological Sciences Division, The University of Chicago, Chicago, Illinois 60637 Department of Pathology, Shenzhen People's Hospital Shenzhen 518001, Guangdong Province, P. R. China. Institute of Microsurgery on Extremities Shanghai Jiao Tong University Affiliated Sixth People's Hospital China Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27517-7248;; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27517-7248; Shanghai Key Lab of Tuberculosis Shanghai Pulmonary Hospital Tongji University School of Medicine Shanghai China Faculty of Geographical Science, Beijing Normal University, Beijing 100875, China Department of Urology, Shanghai Fifth People’s Hospital, Fudan University, Shanghai 200240, China Department of Radiology Changhai Hospital, Navy Military Medical University Shanghai China Department of Mathematics, Michigan State University, East Lansing, MI 48824, USA Key Laboratory of Animal Diseases Diagnostic and Immunology, College of Veterinary Medicine, Nanjing Agricultural University, Ministry of Agriculture, Nanjing, People’s Republic of China (Zhang, Lu, Y. Wang, S. Wang, Fan); Department of Animal Science and Technology, Jinling Technology Institution, Nanjing, People’s Republic of China (Zhang, Dai, Chen) Institute of Food Science and Technology, College of Biological Science and Engineering Fuzhou University Fuzhou China; Fujian Center of Excellence for Food Biotechnology Fuzhou University Fuzhou China Department of Thoracic Oncology II, Peking University Cancer Hospital & Institute Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Beijing China College of Chemistry, Fuzhou University, Fuzhou 350116, People’s Republic of China The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, Jiangsu 214122, China; The Science Center for Future Foods, Jiangnan University, Wuxi, Jiangsu 214122, China School of Safety Science and Engineering, Henan Polytechnic University, Jiaozuo, Henan 454003, China From the Department of Neurosurgery & Brain and Nerve Research Laboratory, The First Affiliated Hospital of Soochow University, Suzhou, China (H.S., Z.C., Y.W., A.G., H.L., Y.C., L.Z., X.X., Z.W., G.C.); and Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, Anhui Province Key Laboratory of Brain Function and Brain Disease, Hefei, Anhui, China (Y.W.). Department of Gastroenterology, Shulan (Hangzhou) Hospital, Hangzhou, Zhejiang Province, People’s Republic of China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China The Affiliated Stomatology Hospital Zhejiang University School of Medicine Hangzhou China; Key Laboratory of Oral Biomedical Research of Zhejiang Province Zhejiang University School of Stomatology Hangzhou China Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, D-07745 Jena, Germany; Key Laboratory of Cognition & Personality Southwest University Chongqing China Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, United States College of Animal Science and Technology Henan University of Science and Technology LuoyangChina; Key Laboratory of Molecular Pathogen and Immunology of Animal of Luoyang LuoyangChina Department of Hematology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China. Institute of Microsurgery on Extremities Department of Orthopedic Surgery Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, PR China First Affiliated Hospital of Nanchang University The Institute of Chemical Physics, Key Laboratory of Cluster Science, School of Chemistry, Beijing Institute of Technology, Beijing 100081, People’s Republic of China La Follette School of Public Affairs University of Wisconsin–Madison Madison WI USA Department of Environmental Science and Engineering, Tsinghua University, Beijing 100084, China. wangyang00@mails.tsinghua.edu.cn College of Life Sciences/Key Laboratory of Forest Tree Genetic Improvement and Biotechnology (Ministry of Education), Northeast Forestry University, Harbin 150040, China, Department of Biology, UF Genetics Institute, and Plant Molecular & Cellular Biology Program, University of Florida, Gainesville, Florida 32611, and Proteomics Facility, Interdisciplinary Center for Biotechnology Research, University of Florida, Gainesville, Florida 32610 First affiliated hospital of Xinjiang Medical University, Urumqi, China First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300112, China Medical Research and Biometrics Center, National Center for Cardiovascular Diseases, Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China (mainland) Department of Nephrology, First Medical Center of Chinese PLA General Hospital, Nephrology Institute of the Chinese People’s Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research , No. 28 Fuxing Road, Haidian District , Beijing 100853 , People’s Republic of China Beijing University of Chinese Medicine, Beijing 100029, China Shenzhen Institute for Drug Control Shenzhen China; Shenzhen Key Laboratory of Drug Quality Standard Research Shenzhen China Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA; Department of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, China Department of Pharmacology and Chemical Biology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China Department of Material and Chemical Engineering Zhengzhou University of Light Industry No. 100 Kexue Street Zhengzhou Henan 450002 P. R. China Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing100191, China Department of Chemistry; York University; Toronto; Canada M3J 1P3 Department of Hematology, Xuzhou Central Hospital, Xuzhou 221009, Jiangsu Province, China. Department of Oral Radiology West China Hospital of Stomatology, West China School of Stomatology Sichuan University, State Key Laboratory of Oral Diseases Chengdu China Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry Chinese Academy of Sciences Beijing 100190 China; School of Future Technology University of Chinese Academy of Sciences Beijing 100049 China Laboratory of Advanced Optoelectronic Materials Suzhou Key Laboratory of Novel Semiconductor‐optoelectronics Materials and Devices College of Chemistry, Chemical Engineering and Materials Science Soochow University Suzhou 215123 China Engineering Research Center of Nano-Geomaterials of Ministry of Education Faculty of Materials Science and Chemistry China University of Geosciences Wuhan 430074 P. R. China; Division of Chemistry and Biological Chemistry School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link 637371 Singapore Singapore Department of Radiology Sixth Affiliated Hospital of Shenzhen University Shenzhen China Department of Clinical Laboratory, Yan'an Hospital Affiliated to Kunming Medical University, Kunming, Yunnan 650051, P.R. China Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China Department of Biometrics, National Centre for Cardiovascular Disease, Cardiovascular Institute & Fu Wai Hospital, CAPM & PUMC, Beijing 100037, China. Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes; Institute of Life and Health Engineering; College of Life Science and Technology; Jinan University; Guangzhou 510632 Department of Surgery School of Medicine Technical University of Munich Munich Germany Department of Nuclear Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China. Medical Research & Biometrics Center (Yang Wang), Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. MassBiologics of the University of Massachusetts Medical School, Boston, Massachusetts 02126, United States Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China National Clinical Research Center for Obstetrics and Gynecology (Peking University Third Hospital), Beijing 100191, China National R&D Center for Citrus Preservation, Key Laboratory of Horticultural Plant Biology, Ministry of Education, Huazhong Agricultural University, Wuhan, P.R. China Department of Radiation Oncology, Yantai Yuhuangding Hospital, Yantai, Shandong, China College of Pharmaceutical Sciences Texas Southern University Houston TX 77004 USA Department of Nephrology, The 8th Medical Center of Chinese PLA General Hospital, Beijing 100091, China Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI School of Fundamental Sciences, China Medical University, Shenyang 110122, People's Republic of China State Key Laboratory of Natural Medicines (China Pharmaceutical University), School of Life Science & Technology China Pharmaceutical University Nanjing 210009 People's Republic of China Department of Urology First Affiliated Hospital of Nanjing Medical University Nanjing China School of Environmental & Chemical Engineering, Xi’an Polytechnic University, Xi’an, Shaanxi 710048, P. R. China Specialty Corn Institute, College of Agronomy, Shenyang Agricultural University, Shenyang 110866, China State Key Laboratory of Applied Organic Chemistry College of Chemistry and Chemical Engineering Frontiers Science Center for Rare Isotopes Lanzhou University Lanzhou Gansu 730000 P. R. China The College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou, Henan Province 450001, P. R. China College of Life Science, Northeast Forestry University, Harbin 150040, China; 5Shanxi Academy of Advanced Research and Innovation, Taiyuan, China. Department of Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, MD, United States Department of Ultrasound; China-Japan Union Hospital of Jilin University; Changchun; P. R. China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China. Department of Hand Surgery, Union Hospital, Tongji Medical College Huazhong University of Science and Technology Wuhan China National Clinical Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, Jiangsu 210016, China State Key Lab of Reproductive MedicineNanjing Medical UniversityNanjingChina College of Materials Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China Instituto Madrileño de Estudios Avanzados en Nanociencias (IMDEA-Nanociencia), Cantoblanco, 28049 Madrid, Spain Center for Traditional Chinese Medicine and Systems Biology, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China Department of Neurosurgery & Brain and Nerve Research Laboratory The First Affiliated Hospital of Soochow University Suzhou China The College of Chemistry and Molecular Engineering, Center of Computational Chemistry, Zhengzhou University, Zhengzhou, Henan Province 450001, P.R. China The College of Chemistry and Molecular Engineering; Center of Computational Chemistry; Zhengzhou University; Zhengzhou; P.R. China School of Future Technology, Xi’an Jiaotong University, Xi’an 710049, Shaanxi, People’s Republic of China Key Laboratory of Bioorganic Synthesis of Zhejiang Province, College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China; Engineering Research Center of Bioconversion and Biopurification of Ministry of Education, Zhejiang University of Technology, Hangzhou, China; National and Local Joint Engineering Research Center for Biomanufacturing of Chiral Chemicals, Zhejiang University of Technology, Hangzhou, China *Committee on Immunology and Department of Pathology, University of Chicago, Chicago, IL 60637; Tianjin University of Traditional Chinese Medicine, Tuanbo New Town, China Antibody Engineering Laboratory, State Key Laboratory of Natural Medicines, School of Life Science & Technology, China Pharmaceutical University, Nanjing Department of Thoracic Oncology II, Peking University Cancer Hospital & Institute, Beijing, China Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu 610041, China Department of Neurology, Shenzhen University 1st Affiliated Hospital, Guangdong, China The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation the Key Laboratory of Chemical Biology of Fujian Province State Key Laboratory of Physical Chemistry of Solid Surfaces Collaborative Innovation Center of Chemistry for Energy Materials Department of Chemical Biology College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China Key Laboratory of High Power Laser Materials, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China Medical Research and Biometrics Center, National Center for Cardiovascular Disease, Beijing 102300, China National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China; Graduate University of Chinese Academy of Sciences, Beijing, 100049, China College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471003, China; Key Lab of Animal Bacteriology, Ministry of Agriculture, Nanjing Agricultural University, Nanjing 210095, China; OIE Reference Laboratory for Swine Streptococcosis, Nanjing 210095, China State Key Laboratory of Infrared Physics, Shanghai Institute of Technical Physics, Chinese Academy of Sciences, Shanghai 200083, China College of Water Resources and Civil Engineering, China Agricultural University, Beijing 100083, China School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, PR China; Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, Florida 33620, United States Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, and State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100871, China Medical Research and Biometrics Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China State Key Lab. of Electrical Insulation and Power Equipment, Xi'an Jiaotong University; Xi'an 710049; China Department of Radiotherapy, Huashan Hospital Fudan University Shanghai China Department of Pathology, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine Betta Pharmaceuticals Co., Ltd, Hangzhou 311100, China. Key Laboratory of Coalbed Methane Resources and Reservoir Formation Process, Ministry of Education, China University of Mining and Technology, Xuzhou, Jiangsu 221008, China Department of Human Genetics, Emory University, Atlanta, GA 30084; People's Hospital of Wuxi Huishan District, Wuxi, Jiangsu 214187, China. Academy of State Administration of Grain, Beijing, People’s Republic of China Department of Spinal Surgery, Ningbo No.6 Hospital, Ningbo, China National Laboratory of Solid State Microstructures College of Engineering and Applied Sciences and Collaborative Innovation Center of Advanced Microstructures Nanjing University 16 Jinyin Street Nanjing 210093 P. R. China Collaborative Innovation Center for Respiratory Diseases Diagnostics, Treatment and New Drug Research and Development of Henan University of Traditional Chinese Medicine (TCM); Department of Respiratory Diseases, the First Affiliated Hospital of Henan University of TCM Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China Department of TÇM Tongren Hospital Shanghai, Jiao Tong University School of Medicine Shanghai China Department of Hepatobiliary and Pancreatic Surgery, Zhongda Hospital Affiliated to Southeast University , Nanjing , 210009 , China School of Computer Science and Technology, Chongqing University of Posts and Telecommunications, Chongqing 400065, China Department of Biology and Molecular Biology Institute, San Diego State University, San Diego, CA 92182 The College of Chemistry and Molecular Engineering, Center of Computational Chemistry, Zhengzhou University, Zhengzhou, Henan Province 450001, P. R. China Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, No. 17 Lujiang Road, Hefei, 230001 Anhui Province, China Department of Critical Care Medicine, Zhejiang Hospital, Hangzhou 310013, Zhejiang, China (Wang Y is working at Department of Critical Care Medicine, Ningbo No.2 Hospital). Corresponding author: Cai Guolong, Email: caiguolong@126.com. Department of Maternal, Child and Adolescent Health, Anhui Medical University School of Public Health, Hefei, Anhui 230032, China Joseph J. Zilber School of Public Health, University of Wisconsin–Milwaukee, Milwaukee, WI, USA State Key Laboratory of Heavy Oil Processing, China University of Petroleum, Qingdao 266580, China State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China Chengdu 610054 P. R. China Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Materials; Center for Excellence in Molecular Synthesis; Shanghai Institute of Organic Chemistry; University of Chinese Academy of Sciences; CAS Department of Applied Physics The Hong Kong Polytechnic University Hung Hom, Kowloon Hong Kong P. R. China Department of Plant Biology, Rutgers University, New Brunswick, New Jersey 08901, United States Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science Beijing Normal University, Beijing, China; Department of Thoracic Oncology II, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Peking University Cancer Hospital and Institute Beijing China Personnel Department Guang Xi University of Chinese Medicine Nanning China Department of Ultrasound, Chinese People's Liberation Army General Hospital, Beijing, People's Republic of China Department of Chemistry, School of Science Beijing Jiaotong University Beijing 100044 P. R. China Key Laboratory of Animal Antimicrobial Resistance Surveillance, Ministry of Agriculture and Rural Affairs and Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University , Beijing, 100193 , China Department of Plastic Surgery, General Hospital of Shenyang Military Area Command, PLA, Liaoning - China Jiangnan University Medical Center Jiangnan University Wuxi 214002 China Laboratory of Animal Physiology, Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan Department of Prevention and Health Care, The Hospital of Health Science Center, Peking University, Beijing, China Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China Key Laboratory of Precision and Intelligent Chemistry, School of Chemistry and Materials Science, University of Science and Technology of China , China Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington 99354, United States Key Laboratory of Cultivation and Protection for Non-Wood Forest Trees (Ministry of Education), Central South University of Forestry and Technology, Changsha 410004, China School of Chemistry and Chemical Engineering Nantong University Nantong China Jiangsu Sobute New Materials Co., Ltd., Nanjing 211103, China Department of Emergency, The 8th People's Hospital of Shanghai, Shanghai, P.R. China Aix-Marseille Université; CNRS; CINaM UMR 7325; Marseille, France; College of Chemistry and Molecular Sciences Department of Biological Engineering Massachusetts Institute of Technology Cambridge Massachusetts Key Laboratory for Intelligent Nano Materials and Devices of Ministry of Education, State Key Laboratory of Mechanics and Control of Mechanical Structures, and Institute for Frontier Science, Nanjing University of Aeronautics and Astronautics, Nanjing, 210016, China Department of Emergency, Changhai Hospital, Naval Military Medical University, Shanghai, China; Department of Orthopedics, Changhai Hospital, Naval Military Medical University, Shanghai, China Key Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, 174 Shazheng Street, Chongqing 400030, People's Republic of China The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, People’s Republic of China Graduate School Jinzhou Medical University Jinzhou China Department of Urology; The Fifth People's Hospital of Shanghai, Fudan University; Shanghai China Department of Chemistry Simon Fraser University 8888 University Drive Burnaby British Columbia V5A 1S6 Canada; Current address: China and Laboratory for Marine Drugs and Bioproducts Qingdao National Laboratory for Marine Science and Technology (QNLM) Qingdao 266237 China National Clinical Research Center for Otolaryngologic Diseases College of Otolaryngology–Head and Neck Surgery Chinese PLA General Hospital Beijing China Key Laboratory of Development and Evaluation of the Chemical and Herbal Drugs for Animal Use, Ministry of Agriculture of The People's Republic of China, College of Veterinary Medicine, China Agricultural University, Beijing, The People's Republic of China. Department of Material and Chemical Engineering Zhengzhou University of Light Industry 136 Science Avenue Zhengzhou Henan Province 450002 P. R. China Key Laboratory of Inorganic Coating Materials CAS, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 201800, China; State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou, China State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Key Laboratory of Biomedical Engineering Chongqing Medical University Chongqing China Department of Oral and Maxillofacial Surgery; and State Key Laboratory of Electronic Thin Films and Integrated Devices University of Electronic Science and Technology of China Chengdu 610054 Sichuan P. R. China College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China; Key Laboratory of Molecular Pathogen and Immunology of Animal of Luoyang, Luoyang, China Department of Cardiology General Hospital of Ningxia Medical University Yinchuan China Provincial Key Laboratory of Oil & Gas Chemical Technology College of Chemistry & Chemical Engineering Northeast Petroleum University Daqing 163318 P. R. China MOE Key Laboratory for Biosystems Homeostasis and Protection and Innovation Center for Cell Signaling Network Life Sciences Institute Zhejiang University Hangzhou 310058 China Biostatistics and Epidemiology, and MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes Institute of Life and Health Engineering College of Life Science and Technology Jinan University Guangzhou 510632 China Department of Biomedical Research, National Jewish Health, Denver, CO 80206; Department of Applied Chemistry, School of Engineering, University of Toyama, Gofuku 3190, Toyama 930-8555, Japan; College of New Energy, State Key Laboratory of Heavy Oil Processing, China University of Petroleum (East China), Qingdao 266580, China School of Basic Medical Sciences, Anhui Medical University Hefei 230022, Anhui, China. Department of Materials Science and Engineering University of California Los Angeles California 90095 USA Central China Normal University Wuhan Hubei China Academy of Frontier Sciences, Southwest Jiaotong University, Chengdu 610031, China Department of Orthopedics, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, P. R. China State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology; College of Chemical and Environmental Engineering; Shandong University of Science and Technology; Qingdao 266590; China Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, China Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, 600 Yishan Road, Shanghai, 200233, China Department of Cardiovascular Medicine The Fourth Affiliated Hospital of China Medical University Shenyang China §MassBiologics of the University of Massachusetts Medical School, Boston, MA 02126 Department of Dermatology and Venerology Peking University First Hospital Beijing China Department of Clinical Immunology School of Medical Laboratory Tianjin Medical University Tianjin China Department of Pediatrics, First Affiliated Hospital of Anhui Medical University, Hefei, Anhui Province 230032, P.R.China. Department of Radiology The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Nanjing 210008 P.R. China RIKEN Nishina Center for Accelerator-Based Science, 2-1 Hirosawa, Wako 351-0198, Saitama, Japan Institute of Rocket Force Medicine State Key Laboratory of Trauma, Burns and Combined Injury Third Military Medical University Chongqing China Department of Interventional Therapy, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China Department of Cardiovascular Medicine First Affiliated Hospital of Xi'an Jiaotong University Xi'an China; Key Laboratory of Molecular Cardiology of Shaanxi Province Xi'an China The Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China Strait Institute of Flexible Electronics (SIFE, Future Technologies), Fujian Normal University, Strait Laboratory of Flexible Electronics (SLoFE), Fuzhou, Fujian 350117, China Department of General Surgery, The First People's Hospital of Neijiang, Neijiang, 641000 Sichuan Province, China Key Laboratory of Precision and Intelligent Chemistry University of Science and Technology of China Hefei 230026 China Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences Peking Union Medical College Beijing China Medical Research & Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College , No. 167 Beilishi Road, Xicheng District, Beijing 100037, People's Republic of China Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, Liaoning 110016, P. R. China Section of Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education), Shaanxi Key Laboratory for Animal Conservation, College of Life Science, Northwest University, Xi’an, PR China;; College of Biology Pharmacy and Food Engineering, Shangluo University, Shangluo, PR China; Department of Chemistry, School of Forensic Medicine, China Medical University, Shenyang 110122, China Key Laboratory of Environmental Optical & Technology, Anhui Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Hefei 230031, China. ywang@aiofm.ac.cn Institute for Decarbonization Materials, University of California, Berkeley, California 94720, United States; Department of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, United States Department of Clinical Laboratory Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 P. R. China; Hubei Key Laboratory of Regenerative Medicine and Multi‐disciplinary Translational Research Research Center for Tissue Engineering and Regenerative Medicine Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 P. R. China Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences Xi’an Jiaotong University Health Science Center Xi’an China Department of Ultrasound; China-Japan Union Hospital of Jilin University; Changchun; P.R. China Department of Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China Key Laboratory of Cognition and Personality, Southwest University, Chongqing, China Department of Obstetrics and Gynecology, International Peace Maternity and Child Health Hospital, School of Medicine Shanghai Jiaotong University Shanghai China; Shanghai Key Laboratory Embryo Original Diseases Shanghai China Institute of Immunotherapy, Fujian Medical University, Minhou County, Fuzhou, China School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, People’s Republic of China Department of Radiology Changhai Hospital, Second Military Medical University Shanghai China School of Life Sciences, Jilin University, Changchun 130012, China Space Engineering University The Key Laboratory of Industrial Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi 214122 China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of Education Jiangnan University Wuxi 214122 China Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China First Affiliated Hospital of Sun Yat-Sen University , GuangZhou , GuangDong , China Department of Tissue Enguneering, School of Intelligent Medicine, China Medical University, Shenyang, China.; Department of Chemistry, School of Forensic Medicine, China Medical University, Shenyang, China. State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Nanjing 211816 P. R. China Presbyterian Kaseman Hospital, Albuquerque, New Mexico Department of Pharmaceutical and Biological Engineering, School of Chemical Engineering Sichuan University Chengdu People's Republic of China The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Frontiers Science Research Base of Biomimetic Catalysis Shanghai Key Laboratory of Rare Earth Functional Materials Department of Chemistry Shanghai Normal University 100 Guilin Road Shanghai 200234 China. Institute for Geriatrics, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China; Collaborative Innovation Center for Respiratory Diseases Diagnostics, Treatment and New Drug Research and Development in Henan Province, Zhengzhou, Henan 450046, China School of Medicine University of Missouri Columbia Missouri USA; Bond Life Sciences Center University of Missouri Columbia Missouri USA Lundberg-Kienlen Lung Biology and Toxicology Laboratory, Department of Physiological Sciences, Oklahoma State University, Stillwater, Oklahoma; and Institute of Microsurgery on Extremities Shanghai Jiaotong University Affiliated Sixth People' Hospital No. 600 Yishan Road Shanghai 200233 China Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes; Institute of Life and Health Engineering; College of Life Science and Technology; Jinan University; Guangzhou China Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan Department of Orthopedics, The Second Norman Bethune Hospital of Jilin University, Changchun, Jilin 130000, P.R. China Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China; College of Environmental and Chemical Engineering, Xi’an Polytechnic University, Xian, China Departments of Pathology Chang Hai Hospital The 2nd Military Medical University Shanghai, China The Army Engineering University of PLA, Nanjing, China Shenzhen Institute for Drug Control Shenzhen P. R. China; Shenzhen Key Laboratory of Drug Quality Standard Research Shenzhen P. R. China Laboratory of Ethnopharmacology, Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital Central South University Hunan Changsha P. R. China Department of Medicinal Chemistry School of Pharmacy Fudan University Shanghai China Department of Materials Science and Engineering and The Shenzhen Key Laboratory for Printed Organic Electronics, Southern University of Science and Technology (SUSTech), No. 1088, Xueyuan Road, Shenzhen 518055, Guangdong, China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry; Chinese Academy of Sciences; Changchun 130022; P. R. China; University of the Chinese Academy of Sciences Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan, 430074, P. R. China Key Lab of Microbiological Engineering Agricultural Environment, Ministry of Agriculture, College of Life Science, Nanjing Agricultural University, Nanjing 210095, China. State Key Laboratory of Electronic Thin Films and Integrated Devices; University of Electronic Science and Technology of China; Chengdu 610054; P. R. China 1State Key Lab of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu, China Division of Chemistry and Biological Chemistry School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link 637371 Singapore State Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, PR China; University of Chinese Academy of Sciences, Beijing 100049, PR China Lab of Medical & Molecular Genetics, Department of Medical Genetics, Shanghai Second Medical University, Shanghai 200025, China. 1Department of Pharmaceutics, Rutgers, The State University of New Jersey, Piscataway, New Jersey; Department of Chemistry and Low Carbon Energy Research Center National Tsing Hua University Hsinchu 30013 Taiwan MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China Co-Innovation Center for Efficient Processing and Utilization of Forest Products, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China The Department of Urology of Shenzhen Qianhai Shekou Free Trade Zone Hospital, Shenzhen, China. State Key Laboratory of Esophageal Cancer Prevention & Treatment, School of Pharmaceutical Sciences Department of Laboratory Medicine Yale University School of Medicine New Haven CT USA Department of Pathology, Shanghai Changhai Hospital, Second Military Medical University, Shanghai, China Research Institute of Frontier Science, Southwest Jiaotong University, Chengdu 610031, China State Key Laboratory of Infrared Physics Key Laboratory of Intelligent Infrared Perception Shanghai Institute of Technical Physics Chinese Academy of Sciences Shanghai 200083 China Department of Hepatobiliary Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050000, P.R. China University of the Chinese Academy of Sciences School of Chemical Sciences CHINA Laboratory of Molecular Materials and Devices State Key Laboratory of Molecular Engineering of Polymers Department of Materials Science Fudan University 2005, Songhu Road Shanghai 200438 P. R. China Molecular Oncology Department of Cancer Research Institute the First Affiliated Hospital of China Medical University Shenyang Liaoning Province China Institute of Cancer Stem Cell, Dalian Medical University, Dalian, China. yangwang@dmu.edu.cn. Corteva Agriscience, Agriculture Division of DowDuPont Johnston IA USA School of Pharmacy, Anhui Province Key Laboratory of Major Autoimmune Diseases, Anhui Institute of Innovative Drugs, Anhui Medical University, Hefei, P. R. China; Intelligent Transport Systems Research Center (ITSC) Wuhan University of Technology Wuhan China; National Engineering Research Center for Water Transport Safety (WTSC) Wuhan University of Technology Wuhan China Hepatobiliary Pancreatic Tumor Center Chongqing University Cancer Hospital Chongqing China 4Shanxi Academy of Advanced Research and Innovation, Taiyuan, China. Institute of Biotechnology; Shanxi University; Taiyuan 030006; China Alkali Soil Natural Environmental Science Center, Northeast Forestry University, Harbin 150040, China; Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, Harbin 150040, China Kelly N.H. Nudelman, Brenna C. McDonald, Yang Wang, Dori J. Smith, John D. West, Darren P. O'Neill, Victoria L. Champion, Bryan P. Schneider, and Andrew J. Saykin, Indiana University School of Medicine; Noah R. Zanville and Victoria L. Champion, Indiana University School of Nursing, Indianapolis, IN; and Yang Wang, Medical College of Wisconsin, Milwaukee, WI. Department of Urology, Jiangnan University Medical Center, Wuxi 214000, China; Department of Urology, Affiliated Wuxi Clinical College of Nantong University, Nantong 226007, China State Key Laboratory of Electronic Thin Films and Integrated Devices, University of Electronic Science and Technology of China, Chengdu 610054, China. Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China; National Clinical Research Center of Cancer, Tianjin, China; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China Haikou Marine Geological Survey Center, China Geological Survey, Haikou 570100, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China Faculty of Medicine, School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, People’s Republic of China Nishina Center for Accelerator-Based Science, RIKEN, Hirosawa, Wako-shi, Saitama 351-0198 Japan College of Life Science and Technology, Jinan University, Guangzhou, China College of Chemistry and Chemical Engineer; Nantong University; Nantong; P. R. China Chinese Academy of Sciences (CAS); University of Chinese Academy of Sciences Department of Pediatrics, Comer Children's Hospital, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University , Wuxi 214122 , China; Science Center for Future Foods, Jiangnan University , Wuxi 214122 , China School of Resources and Environment, Northeast Agricultural University, Harbin 150030, China State Key Laboratory of Crop Stress Biology in Arid Areas, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences Northwest A&F University Yangling P. R. China College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China Respiratory Digestive Geriatrics, Huzhou Third People’s Hospital, Huzhou, China State Key Laboratory of Crop Stress Biology for Arid Areas and College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, China State Key Laboratory of Microbial Technology; Shandong University; Jinan China State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources School of Chemistry and Pharmaceutical Science Guangxi Normal University Guilin 541004 China Key Laboratory of Molecular Epigenetics of the Ministry of Education, Northeast Normal University, Changchun, Jilin, 130024, People's Republic of China; Department of Traditional and Western Medical Hepatology, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, Rice Research Institute Sichuan Agricultural University Chengdu China; College of Agricultural Science, Panxi Crops Research and Utilization Key Laboratory of Sichuan Province Xichang University Liangshan China College of Public Health, University of Nebraska Medical Center, 984350 Nebraska Medical Center, Omaha, NE 68198-4350, USA School of Pharmacy, Anhui Medical University, Hefei, PR China School of Mechanical Instrumental Engineering, Harbin Institute of Technology, Harbin 150001, China School of Mechanical, Electronic, and Industrial Engineering University of Electronic Science and Technology of China Chengdu Sichuan China School of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine Department of Emergency, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China Key Laboratory for Soft Chemistry and Functional Materials, Ministry of Education, School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing, 210094 Jiangsu, China aCommittee on Immunology and the Department of Pathology, University of Chicago, Chicago, Illinois 60637 State Key Laboratory of Electronic Thin Films and Integrated Devices; School of Optoelectronic Information; University of Electronic Science and Technology of China (UESTC); Chengdu 610054; China Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390; Key Laboratory of Food Nutrition and Safety; Ministry of Education of China; Tianjin University of Science and Technology; Tianjin 300457, P. R. China Zilber School of Public Health, University of Wisconsin–Milwaukee, Milwaukee The State Key Laboratory of Cardiovascular Disease Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China College of Materials, Fujian Key Laboratory of Advanced Materials, Xiamen University, Xiamen 361005, Fujian China School of Chemistry and Materials Science, Collaborative Innovation Center of Chemistry for Energy Materials, University of Science and Technology of China, Hefei, Anhui 230026, P.R. China Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China College of Veterinary Medicine, China Agricultural University, Beijing 100193, P. R. China Surface Science Center, Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, and National Energy Technology Laboratory, Pittsburgh, Pennsylvania 15236 School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan, Hubei 430074, People’s Republic of China College of Pharmacy of Liaoning University, Shenyang, Liaoning 110036, P.R. China | API Engineering Technology Research Center of Liaoning Province, Shenyang, Liaoning 110036, P.R. China | Small molecular targeted drug R&D Engineering Research Center of Liaoning Province, Shenyang, Liaoning 110036, P.R. China Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, China Physical and Computational Sciences Directorate and Institute for Integrated Catalysis, Pacific Northwest National Laboratory 1 , Richland, Washington 99354, USA Department of Thoracic Surgery, The First People’s Hospital of Yunnan Province, Kunming, Yunnan, P.R. China. School of Biological Science and Medical Engineering, Key Laboratory for Biomechanics and Mechanobiology, Beihang Univeristy, Beijing 100083, China College of Physics and Center of Quantum Materials and Devices Chongqing University Chongqing 401331 China Institute of Combined Injury State Key Laboratory of Trauma, Burns and Combined Injury Chongqing Engineering Research Center for Nanomedicine College of Preventive Medicine Third Military Medical University Chongqing 400038 China Element Inc, New York, NY, USA Department of Chemistry, University of Illinois at Urbana−Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States MassBiologics of the University of Massachusetts Medical School, Boston, Massachusetts, USA Nanlou Respiratory Diseases Department, Chinese PLA General Hospital, Chinese PLA Postgraduate Medical School, Beijing, People's Republic of China, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China Departamento de Química, Módulo 13, Universidad Autónoma de Madrid, 28049 Madrid, Spain College of Materials Science & Engineering Zhejiang; University of Technology; Hangzhou 310014; China Department of Sports Medicine First Affiliated Hospital of Kunming Medical University Kunming Yunnan China Department of Thoracic Surgery Beijing Chaoyang Hospital Beijing Chaoyang China State Key Lab of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China Hefei National Laboratory for Physical Sciences at the Microscale, Department of Chemistry, Hefei Science Center of CAS, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China Department of Gastroenterology, Peking University People’s Hospital, Beijing, China; Clinical Center of Immune-Mediated Digestive Diseases, Peking University People’s Hospital, Beijing, China State Key Laboratory of Crop Gene Exploration and Utilization in Southwest China Rice Research Institute Sichuan Agricultural University Chengdu China Department of Galactophore Surgery Weifang People's Hospital Weifang PR China Key Laboratory of Mesoscopic Chemistry of MOE; Collaborative Innovation Center of Chemistry for Life Sciences; School of Chemistry and Chemical Engineering; Nanjing University; Nanjing 210023 Department of Pharmacy, The 3rd Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan, China College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, People’s Republic of China Department of Pathology, Shanghai Fourth People’s Hospital Affiliated to Tongji University School of Medicine, Shanghai, China. School of Biological Sciences, Hebei Normal University, Shijiazhuang, People's Republic of China Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, Liaoning, China. College of Chemical Engineering, Sichuan University, Chengdu 610065, PR China Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning 121001, China Shenzhen Huada Gene Research Institute, Shenzhen, Guangdong, China Department of Histology and Embryology Institute of neuroscience Wenzhou Medical University Wenzhou P. R. China Department of Orthopaedics, China-Japan Union Hospital of Jilin University, Changchun, China National Laboratory of Solid State Microstructures, College of Engineering and Applied Sciences, Jiangsu Key Laboratory of Artificial Functional Materials, Nanjing University, Nanjing 210093, P. R. China. Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, Baltimore, MD, United States; Center to Advance Chronic Pain Research, University of Maryland, Baltimore, Baltimore, MD, United States State Key Laboratory of Natural Medicines and Laboratory of Chemical Biology, China Pharmaceutical University, Nanjing, Jiangsu Province, 210009, People's Republic of China From the Department of Anesthesiology (S.C.J.), Allegheny General Hospital, Pittsburgh, Pa; and the Cleveland Clinic Foundation (Y.W., W.H., A.D.P.-T., T.C.N., A.J.F., A.W.M.), Cleveland, Ohio. College of Material Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, China Institute of Hematology, Changhai Hospital Naval Medical University (Second Military Medical University) Shanghai China Department of Gynaecology and Obstetrics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University Guangzhou 510120, China. Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China. Guang An Men Hospital, China Academy of Chinese Medical Sciences; Department of Acupuncture and Moxibustion; No. 5, Bei Xian Ge Street Beijing China 100053 State Key Lab of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China MOE Key Laboratory of Tumor Molecular Biology and Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, Jinan University Guangzhou China School of Acupuncture, Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, China Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China; National Clinical Research Center for Skin and Immune Diseases, Beijing, China School of Mechanical Engineering, Beijing Institute of Technology, Beijing 100811, China Departments of Anatomy,Histology, and Embryology,Shanghai Medical School,Fudan University, Shanghai, China Department of Chemistry, Northwestern University, Evanston, IL 60208;; Materials Research Center, Northwestern University, Evanston, IL 60208; Institute of Zhejiang Aquatic Product Technology, Hangzhou310000, China The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, The Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China Department of Interventional and Vascular surgery, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China College of Horticulture, Sichuan Agricultural University, Chengdu, Sichuan, China Faculty of Hepato‐Biliary‐Pancreatic Surgery Chinese People's Liberation Army (PLA) General Hospital, Institute of Hepatobiliary Surgery of Chinese PLA Beijing China Department of Burns, The 202nd Hospital of People's Liberation Army, Shenyang 110003, Liaoning Province. P.R. China. Department of Laboratory, Kunming Yanan Hospital, Kunming, Yunnan 650051, P.R. China State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Science, Guangxi Normal University, Guilin 541004, China Department of Mechanical Engineering, The University of Texas at Dallas, 800 W. Campbell Rd, Richardson, Texas 75080, United States College of Biology Pharmacy and Food Engineering, Shangluo University, Shangluo, China; Shangluo Technology & Research Institute of Chinese Medicinal Materials Integrated Pest Management, Shangluo, China Department of Neurosurgery, Municipal Center Hospital, Xinxiang 453000, China; Email: king13837368673@163.com. Department of Pathology, Shenzhen People’s Hospital, The Second Clinical Medical College, Jinan University, Shenzhen, Guangdong, China School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-xi Road, Shanghai 200050, P. R. China Department of Chemical and Biomolecular Engineering University of California, Berkeley Berkeley CA 94720 USA School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China Department of Plastic Surgery, First Affiliated Hospital Zhejiang University School of Medicine Hangzhou China Department of Medicinal Chemistry, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, People's Republic of China Institute of Reproductive & Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410001, China Department of Anatomy, Shanghai Medical School, FuDan University, Shanghai 210029, China. Department of Orthopedics, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangdong Pharmaceutical University; Guangzhou, Guangdong Province, China Department of Medicinal Chemistry School of Pharmaceutical Science Sun Yat-sen University Guangzhou 510006 China Department of Dermatology, Peking University First Hospital, Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, National Clinical Research Center for Skin and Immune Disease, NMPA Key Laboratory for Quality Control and Evaluation of Cosmetics, Beijing 100034, China College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, People's Republic of China Department of Veterinary Pharmacology, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China Department of Pharmacy Intravenous Admixture Service the First Affiliated Hospital of Harbin Medical University Harbin P. R. China Department of Orthopedics The Second Hospital of Jilin University Changchun Jilin China State Key Laboratory of Materials-Oriented Chemical Engineering; College of Chemical Engineering; Nanjing Tech University; Nanjing 210009; China Laboratory of Ethnopharmacology, Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, 410008 Changsha, China Department of General Surgery, Xin Hua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China College of Chemistry and Chemical Engineering, Qingdao University, Qingdao, Shandong 266071, China Research Center for Analytical Sciences, Northeastern University, Box 332, Shenyang 110004, China Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. wylw915@126.com State Key Laboratory of Cancer Biology and Department of Physiology and Pathophysiology, Fourth Military Medical University , Xi’an, 710032 , China State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments, Tsinghua University, Beijing 100084, China. Department of Plant Pathology Nanjing Agricultural University Nanjing 210095 China; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education) Nanjing 210095 China Acupuncture Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China GuangZhou JingKe Biotech Co., Ltd Guangzhou China Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China; Cuisine Science Key Laboratory of Sichuan Province, Sichuan Tourism University, Chengdu 610100, China Center of Growth, Metabolism and Aging, Key Laboratory of Biological Resources and Ecological Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610064, China Department of Otorhinolaryngology-Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, P.R. China; Department of Otorhinolaryngology-Head and Neck Surgery, Fuyang Hospital of Anhui Medical University, Fuyang, Anhui, P.R. China. Rice Research Institute, Sichuan Agricultural University, Chengdu, China Department of Respiratory Medicine, Qilu Hospital, Shandong University, Jinan, Shandong 250012, China. Department of General Surgery, Shenzhen Hospital of Armed Police Frontier Corps Shenzhen 518029, China. Center for Influenza and Emerging Infectious Diseases, University of Missouri, Columbia, Missouri, USA; Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, Missouri, USA; Bond Life Sciences Center, University of Missouri, Columbia, Missouri, USA Department of Medical Technology, Suzhou Chien-shiung Institute of Technology, Taicang 215411, P. R. China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University , Beijing , China Department of Intensive Care Unit, Ningbo No. 2 Hospital, Ningbo, China Key Laboratory of New Drug Research and Development of Liaoning Province College of Pharmacy Liaoning University Shenyang P. R. China College of Materials Fujian Key Laboratory of Advanced Materials Xiamen Key Laboratory of Electronic Ceramic Materials and Devices Xiamen University Xiamen 361005 China; Now at Strait Institute of Flexible Electronics (SIFE, Future Technologies) Fujian Normal University Fuzhou Fujian 350117 China Department of Thoracic Surgery, The First People's Hospital of Yunnan Province The Affiliated Hospital of Kunming University of Science and Technology Kunming Yunnan China Key Laboratory of Synthetic and Biological Colloids Ministry of Education School of Chemical and Material Engineering Jiangnan University Wuxi 214122 China Robert M. La Follette School of Public Affairs, University of Wisconsin-Madison, Madison, WI, USA State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, No. 381, Wushan Road, Tianhe District, Guangzhou, CN 510641, China Microbiology Beijing National Laboratory for Molecular Sciences; and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education; College of Chemistry; Peking University; Beijing 100871, China Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Department of Interventional Neuroradiology, Beijing, China. Betta Pharmaceuticals Co., Ltd, Hangzhou, People’s Republic of China State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China School of Chemical Engineering; Sichuan University; Chengdu; PR China State Key Laboratory of Analytical Chemistry for Life Science and Collaborative Innovation Center of Chemistry for Life Sciences, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China Medical Research and Biometrics Centre, Fuwai Hospital, National Centre for Cardiovascular Disease, Peking Union Medical College and Chinese Academy of Medical Sciences, Mentougou District, Beijing, China Department of Verification of Traces National Police University of China Shenyang China School of Physical Science and Technology, ShanghaiTech University, Shanghai, China. Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA Department of Materials Science and Engineering, Southern University of Science and Technology (SUSTech), No. 1088, Xueyuan Road, Shenzhen, Guangdong 518055, China Renal Division and Department of Medicine, St. Michael’s Hospital and University of Toronto, Toronto, ON M4X 1B1, Canada; and Department of Medicine, Division of Hematology, Emory University, Atlanta, GA 30322 Institute of Solid Mechanics, Beihang University, Beijing 100191, China; Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, P.R. China Department of Mathematics, The Hong Kong University of Science and Technology, The Hong Kong Special Administrative Region, China Department of Emergency, Changhai Hospital, Second Military Medical University, Shanghai, China; Department of Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai, China Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China (mainland) Department of Clinical Medicine, Guizhou Medical University, Guiyang 550004, Guizhou, China Department of Urology, Hainan Provincial People's Hospital, Hainan - PR China Betta Pharmaceuticals Co., Ltd, Hangzhou, Zhejiang, 311100, China Key Laboratory of Assisted Reproduction, Ministry of Education, Center of Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China Institute for Microsurgery of Limbs Shanghai Sixth Hospital Shanghai Jiao Tong University Shanghai China Key Laboratory of Development and Evaluation of the Chemical and Herbal Drugs for Animal Use, Ministry of Agriculture of the People's Republic of China, College of Veterinary Medicine, China Agricultural University, Beijing, China. College of Life Science, Tarim University/Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin of Xinjiang Production & Construction Corps, Alar 843300, PR China Kosair Children's Hospital Research Institute, Department of Pediatrics, University of Louisville, Louisville, Kentucky; Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky Department of Neurosurgery, Xinxiang Central Hospital, Xinxiang, Henan 453000, China. dbszzy@gmail.com. Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education; Department of Cardiovascular, First Affiliated Hospital of Medical College, Xi’an Jiaotong University Institute of Chemistry Chinese Academy of Sciences; China Beijing Advance Innovation Center for Nutrition and Human Health, College of Veterinary MedicineChina Agricultural University 100193 Beijing China Centre for Urban Public Safety Research, Nankai University, Tianjin 300071, China. Department of Anatomy, Histology and Embryology, Shanghai Medical Center, Fudan University, Shanghai, China College of Materials, Fujian Key Laboratory of Advanced Materials, Xiamen University, Xiamen 361005, China Medical Research & Biometrics Center, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China Department of Orthopedics, Beijing Shijitan Hospital Capital Medical University Beijing China Department of Infectious Diseases of First Hospital of Jilin University Key Laboratory for Zoonosis Research, Ministry of Education, Institute of Zoonosis, College of Veterinary Medicine Jilin University Changchun China State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, College of Plant Protection, Yunnan Agricultural University, Kunming 650201, China National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Innovation Centre of Industrial Fermentation, Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, P.R. China Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China (mainland) Department of Surgery and Biomedical Sciences Cedars Sinai Cancer Institute Los Angeles California College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, P. R. China School of Pharmacy, Anhui Key Laboratory of Bioactivity of Natural Products, Anhui Medical University Hefei China; The Key Laboratory of Anti‐inflammatory and Immune Medicines Ministry of Education, Anhui Medical University Hefei China; Anhui Province Key Laboratory of Major Autoimmune Diseases Anhui Institute of Innovative Drugs Hefei China Department of Laboratory Medicine and Pathology, Yale University School of Medicine; New Haven CT USA Central China Normal University, Wuhan, Hubei, People’s Republic of China Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China for the Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-Based Practice for Improving Quality (REIN-EPIQ) Study Group Department of ECG, The First Affiliated Hospital, Harbin Medical University Harbin 150001, P. R. China. Performance Plants Inc. 1287 Gardiners Road Kingston Ontario K7P 3J6 Canada Davis Heart and Lung Research Institute and Department of Internal Medicine, The Ohio State University College of Medicine, Columbus (A.N.C., S.K.M., M.F., Y.W., E.D.L.). School of Public Health, Southeast University, Nanjing, PR China; Department of Radiology, Indiana University School of Medicine, Indianapolis; State Key Laboratory of Polymer Physics and Chemistry; Changchun Institute of Applied Chemistry; Chinese Academy of Sciences; Changchun 130022; P. R. China Allstar Tech (Zhongshan) Co., Ltd Yanjiang West 1, No.6 Road, Keji Avenue, Torch Hi‐tech Industrial Development Zone Zhongshan Guangdong 528437 P. R. China Division of CT and MRI, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China School of Chemistry and Chemical Engineering, Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing 211189, P. R. China School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, 201418, China Department of Microbiology, New York University, New York, New York, USA; School of Medicine, Tsing Hua University, Beijing, China Department of Mechanical Engineering, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States Department of Integrated Traditional Chinese and Western Medicine, Institute of Integrative Medicine Xiangya Hospital, Central South University Changsha Hunan China; National Clinical Research Center for Geriatric Disorders Xiangya Hospital, Central South University Changsha Hunan China College of Material Science and Engineering, Zhejiang University of Technology, Hangzhou 310014, P. R. China Materials Science and Engineering Program; University of California; La Jolla; USA Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, China Agricultural University, Beijing, China Department of Orthopedics Surgery; Shanghai Jiaotong University Affiliated Sixth People's Hospital; Shanghai 20200233; China Hefei National Laboratory for Physical Sciences at the Microscale Fujian Institute of Innovation of Chinese Academy of Sciences School of Chemistry and Materials Science University of Science and Technology of China Hefei Anhui 230026 China School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, Liaoning, P.R. China Department of Plant Pathology and The Key Laboratory of Plant Immunity, Nanjing Agricultural University, Nanjing, Jiangsu 210095, China; The Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, Jiangsu 210095, China Department of Urology, Affiliated Hospital of Chengdu University, Chengdu, Sichuan, China. College of Veterinary Medicine, Research Center for Animal Disease Control Engineering Shandong Agricultural University Tai`an Shandong 271018 People's Republic of China Neuroscience and Neuroengineering Research Center, Med‐X Research Institute and School of Biomedical Engineering Shanghai Jiao Tong University Shanghai China Institute of Combined Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China Mechanical and Aerospace Engineering, The Ohio State University, Columbus, OH 43210, USA Department of Infectious DiseasesFirst Hospital of Jilin UniversityKey Laboratory for Zoonosis ResearchInstitute of ZoonosisJilin UniversityMinistry of Medical Sciences Changchun China The Department of Neurosurgery, Henanxinxiang Center Hospital, Xinxiang 453000, China. The Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China Medical Research and Biometrics Center, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, State Key Laboratory of Cardiovascular Disease National Center for Cardiovascular Diseases Beijing China Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China CHRISTUS Stehlin Foundation for Cancer Research, Houston, Texas School of Public Health and Management Chongqing Medical University Chongqing China Department of Chemistry, Northwestern University, Evanston, Illinois 60208-3113, United States Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China Department of TCM Tongren Hospital Shanghai Jiao Tong University School of Medicine Shanghai China Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut Engineering Research Center of Nano-Geomaterials of Ministry of Education, Faculty of Materials Science and Chemistry, China University of Geosciences, Wuhan 430074, P. R. China; Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore Department of Plastic Surgery, General Hospital of Shenyang Military Area Command, PLA, Shenyang, Liaoning 110016, P.R. China Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China. Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing 100193, P. R. China Public Health Policy & Administration, Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA Key Laboratory of Green Printing; Institute of Chemistry; Chinese Academy of Sciences; Beijing 100190; P. R. China Department of Hepatobiliary Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, P.R. China 3School of Pharmaceutical Sciences, Shandong University, Jinan, Shandong, P.R. China. State Key Laboratory of Vegetation and Environmental Change, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China; From Department of Pharmacology and Cell Biophysics (W.K.J., G.-C.F., S.L., Y.W., E.G.K., J.E.S., J.L., X.R.), Department of Anesthesiology (J.-M.Z.), Department of Internal Medicine (N.L.W.), Cardiovascular Division, and the Veteran’s Administration Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio. School of Chemical Engineering; Sichuan University; Chengdu 610065; China Department of Hepatobiliary Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, China; Department of Physics; South China University of Technology; Guangzhou; P. R. China MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, China State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China School of Chemistry and Chemical Engineering, Southeast University, Jiangning, Nanjing, Jiangsu 211189, P. R. China Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, MD, United States; Center to Advance Chronic Pain Research, University of Maryland, Baltimore, MD, United States Institute of Neuroscience; Department of Histology and Embryology; Wenzhou Medical University; Wenzhou, China Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University; Key Laboratory of Molecular Cardiology of Shaanxi Province Department of Earth Ocean and Atmospheric Science, Florida State University Tallahassee FL 32306 USA School of Materials Science and Engineering, State Key Laboratory of Silicon and Advanced Semiconductor Materials, Zhejiang University, Hangzhou 310027, People’s Republic of China; Zhejiang Provincial Engineering Research Center of Oxide Semiconductors for Environmental and Optoelectronic Applications, Institute of Wenzhou, Zhejiang University, Wenzhou 325006, People’s Republic of China Department of Thoracic Surgery, The First People’s Hospital of Yunnan Province, Kunming City, Yunnan Province, China State Key Laboratory of Coordination Chemistry; Collaborative Innovation Center of Chemistry for Life Sciences; Center for Multi-molecular Organic Chemistry; School of Chemistry and Chemical Engineering; Nanjing University School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences, Jinan, China.; Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, China. Department of Biomedical Research, National Jewish Health, Denver, Colorado.; Department of Immunology and Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang, P R China; School of Pharmacy, Guizhou Medical University, Guiyang, P R China Department of Chemical Engineering University of Michigan 2300 Hayward Street Ann Arbor MI 48109 USA; Translational Oncology Program University of Michigan 1600 Huron Pkwy Ann Arbor MI 48109 USA; Biointerfaces Institute University of Michigan 2800 Plymouth Road Ann Arbor MI 48109 USA State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of the Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, China Department of Thoracic Surgery, Beijing Chao‐Yang Hospital Capital Medical University Beijing China Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis, Department of Infectious Diseases First Hospital of Jilin University, College of Veterinary Medicine, Jilin University Changchun P. R. China School of Physics, South China University of Technology, Guangzhou 510640, PR China Department of Orthopedics, The Second Hospital of Jilin University, Changchun, China College of Agronomy Gansu Agricultural University Lanzhou 730000 China State Key Laboratory of Plant Environmental Resilience, College of Biological Sciences, China Agricultural University, Beijing 100193, China; College of Biological Sciences, China Agricultural University, Beijing 100193, China School of Chinese Materia Medica, Beijing University of Chinese Medicine Beijing 100029, China. Department of Chemistry; University of Science and Technology of China; Hefei; P. R. China School of Physics Xidian University Xi'an China National Laboratory of Solid State Microstructures, School of Physics, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China Department of Oral and Maxillofacial Surgery, Nanjing Stomatological Hospital Medical School of Nanjing University Nanjing China Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854 Department of Orthopedics, China-Japan Union Hospital of Jilin University Changchun 130033, Jilin, China. Department of Hematology Institute of Hematology Changhai Hospital Naval Medical University Shanghai China Department of Orthopedic Surgery, Shanghai Sixth People’s Hospital, Shanghai Jiao Tong University, Shanghai, China College of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225002, China Department of Medical Imaging, Shandong Provincial Hospital Affiliated to Shandong University, Shandong University, Jinan Hefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, Anhui 230026, People’s Republic of China State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University , Shanghai 200438, China State Key Laboratory for Mechanical Behavior of Materials School of Chemistry Xi'an Jiaotong University Xi'an 710049 China Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China (mainland) Department of Abdominal Surgery, Cancer Institute and Cancer Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, China Department of Radiotherapy, Yantai Yuhuangding Hospital, The Affiliated Hospital of Qingdao University, Yantai 264000, Shandong, China State Key Laboratory and Institute of Elemento-Organic Chemistry; Nankai University; Tianjin 300071; China Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM); National Synergistic Innovation; Center for Advanced Materials (SICAM); Nanjing University of Posts and Telecommunications; Nanjing, P. R. China Department of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing 10020, People’s Republic of China Peking University Cancer Hospital & Institute, Beijing, China Panjin Liaohe Oilfield Gem Flower Hospital, Panjin, Liaoning Province 124010, China. From the *Department of Hepatobiliary and Transplantation Surgery, The First Hospital of China Medical University, Shenyang; †Department of Nuclear Medicine, Changhai Hospital, and ‡Department of Pathology, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai; and §Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Department of Hepatobiliary Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, China Research Institute of Frontier Science, Southwest Jiaotong University, No. 111, North Section 1, Second Ring Road, Chengdu, Sichuan, 610031, China; Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan Department of Cardiovascular, First Affiliated Hospital of Medical College, Xi'an Jiaotong University, China College of Plant Protection, Yunnan Agricultural University, Key Laboratory of Agricultural Biodiversity and Pest Control, Yunnan Kunming 650201, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China; Beijing Laboratory of Food Quality and Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China Immunomedics, Inc., Morris Plains, New Jersey. College of Life Science, Anhui Normal University, Wuhu, China. yangwang-email@163.com Tianjin University of Traditional Chinese Medicine, Tianjin, China Department of Emergency, Changhai Hospital, Naval Military Medical University, Shanghai, People's Republic of China; Department of Orthopedics, Changhai Hospital, Naval Military Medical University, Shanghai, People's Republic of China Orthopaedic Medical Center, The Second Hospital of Jilin University, Changchun 130041, P. R. China Department of Mathematics Michigan State University MI 48824 U.S.A. Departments of Surgery and Cardiology University of Minnesota Hospitals Minneapolis Minnesota USA Jiangsu Key Laboratory of New Power Batteries, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China; Key Laboratory for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Nanjing 210094, China State Key Laboratory of High-Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 201800, P. R. China Faculty of Material Science and Chemistry; China University of Geosciences; Wuhan 430074 P. R. China; Division of Chemistry and Biological Chemistry; School of Physical and Mathematical Sciences; Nanyang Technological University; 21 Nanyang Link 637371 Singapore Department of Oncology Surgery, The First Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an 710061, China. Department of Echocardiography, Fuwai Hospital, National Center for Cardiovascular Diseases Beijing, China. Department of Psychiatry, School of Medicine, Shandong University, Jinan 250012, China. wangyang@sdu.edu.cn State Key Lab of Reproductive Medicine Nanjing Medical University Nanjing China Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China. Department of Physiology, Shihezi University Medical College, Shihezi, Xinjiang 832002, P.R. China School of Life Sciences and MOE Key Laboratory for Protein Science, Tsinghua University Tsinghua-Peking Center for Life Sciences, Beijing Frontier Research Center for Biological Structure, McGovern Institute for Brain Research, State Key Laboratory of Membrane Biology, , Beijing, China show [AuthorQuery id="AQ5" rid="5"] Department of Physiological Sciences, Oklahoma State University, Stillwater, OK 74078, USA. Department of Pathology, Changhai Hospital, Shanghai, People's Republic of China Department College of New Energy, State Key Laboratory of Heavy Oil Processing China University of Petroleum (East China) Qingdao 266580 China; Department of Applied Chemistry Graduate School of Engineering University of Toyama Gofuku 3190 Toyama 930-8555 Japan College of Life Sciences, Wuhan University, Wuhan 430072, PR China Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China. Department of Dermatology and Venereology, Peking University First Hospital, Beijing 100034, China;; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing 100034, China;; National Clinical Research Center for Skin and Immune Diseases, Beijing 100034, China; College of Life Sciences, Northwest A&F University, Yangling, Shaanxi 712100, China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China MOE Key Laboratory of Materials Physics and Chemistry in Extraordinary Conditions, Shaanxi Key Laboratory of Macromolecular Science and Technology, School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi’an, 710072, P. R. China State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, College of New Energy, China University of Petroleum (East China), Qingdao 266580, China Department of Digestive Diseases, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, China Betta Pharmaceuticals Co., Ltd Hangzhou Zhejiang P. R. China Shenyang National Laboratory for Materials Science, Institute of Metal Research (IMR), Chinese Academy of Sciences, 72 Wenhua Road, Shenyang 110016, China; School of Materials Science and Engineering, University of Science and Technology of China (USTC), 72 Wenhua Road, Shenyang 110016, China Department of General Surgery The First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology Kunming China Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm 17165, Sweden Beijing Institute of Hepatology, Beijing You An Hospital, Capital Medical University Beijing China; Beijing Precision Medicine and Transformation Engineering Technology Research Center of Hepatitis and Liver Cancer Beijing China The Laboratory of Physiological Hygiene and the Department of Medicine, The University of Minnesota Accelerator Treatment Site, Harbin Chest Hospital, Harbin, P. R. China Department of Chemistry; Zhejiang University; Hangzhou; China Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China; Women and Children’s Hospital of Chongqing Medical University, Chongqing 400014, China; State Key Laboratory of Maternal and Fetal Medicine of Chongqing Municipality, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China Shanxi Academy of Advanced Research and Innovation, 030032 Taiyuan, China; Department of Neurology, Longgang District People’s Hospital of Shenzhen, Shenzhen, China jDepartment of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Anhui, China Department of Materials Science and Engineering and The Shenzhen Key Laboratory for Printed Organic Electronics, South University of Science and Technology of China (SUSTC), No. 1088, Xueyuan Road, Shenzhen, Guangdong 518055, China Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100190 P. R. China; Engineering Research Center of Nanomaterials for Green Printing Technology Beijing National Laboratory for Molecular Sciences Beijing 100190 P. R. China Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education; Beijing Key Laboratory of Bio-inspired Energy Materials and Devices; School of Chemistry and Environment; Beihang University; Beijing 100191 Guangzhou Jingke Medical Laboratory Guangzhou China Department of Anatomy, Histology and Embryology School of Basic Medical Sciences Fudan University No.138 Yixueyuan Road Shanghai 200032 China Department of Otolaryngology, Head and Neck Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China Physical and Computational Sciences Directorate, Pacific Northwest National Laboratory, P.O. Box 999, Richland, Washington 99352, United States Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China; National Clinical Research Center for Skin and Immune Diseases, Beijing, China; National Medical Products Administration, Key Laboratory for Quality Control and Evaluation of Cosmetics, Beijing, China School of Chemistry and Chemical Engineering, State Key laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, Nanjing 210093, China Division of Nephrology and Hypertension, Department of Internal Medicine, University of Cincinnati, Cincinnati, OH - USA; Dialysis Vascular Access Research Group, Cincinnati, OH - USA School of Materials Science and Engineering, Tianjin University , Tianjin 300350 , China; Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences , Hangzhou , Zhejiang 310022 , China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Biostatistics, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China Statistics Medical Research and Biometrics Center, National Center for Cardiovascular Diseases, Fuwai Hospital, Beijing, China Department of Ophthalmology, Tianjin Medical University General Hospital, Tianjin, China State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan University, Shanghai 200438, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China; Key Laboratory of Genetics & Molecular Medicine of Shenzhen, Shenzhen Center for Disease Control and Prevention, Shenzhen, China Tongchuan People’s Hospital, Tongchuan, Shaanxi 727000, China College of New Energy State Key Laboratory of Heavy Oil Processing China University of Petroleum (East China) Qingdao 266580 China; Department of Applied Chemistry Graduate School of Engineering University of Toyama Gofuku 3190 Toyama 930-8555 Japan School of Chemistry and Chemical Engineering State Key Laboratory of Coordination Chemistry Nanjing University Nanjing 210023 P. R. China Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China Guang’an Men Hospital, China Academy of Chinese Medical Sciences, Beijing, China Key Laboratory of Agricultural Biodiversity and Pest Control, College of Plant Protection, Yunnan Agricultural University, Kunming 650201, China Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China. Maternal and Child Health Hospital of Hubei Province, China; Women and Children’s Hospital of Hubei Province, China; Tongji Medical College, Huazhong University of Science and Technology, China Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Beijing Key Laboratory of Protein Posttranslational Modifications and Cell Function, Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education of China, Peking University, Beijing 100083, P.R. China Center for Traditional Chinese Medicine and Systems Biology; Shanghai University of Traditional Chinese Medicine; Shanghai 201203; P. R. China Shanxi Key Laboratory of Big Data for Clinical Decision Research, Taiyuan, China; School of Management, Shanxi Medical University, Taiyuan, China Group of DNA Metabolism, State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai 200031, China. Zhejiang Tea Group Co., Ltd., Hangzhou 310003, China Department of Orthopaedics, Second Affiliated Hospital of Chongqing Medical University, China. Department of Neurology, Qingpu Branch of Zhongshan Hospital, Fudan University, Shanghai 201700, China Institute of Basic Medicial Sciences, Qi Lu Hospital, Shandong University, Jinan, Shandong Province, 250012, P.R.China College of Water Resources and Civil Engineering, China Agricultural University, Beijing, People's Republic of China; Key Laboratory of Agricultural Engineering in Structure and Environment, Ministry of Agriculture and Rural Affairs, Beijing, People's Republic of China; Beijing Engineering Research Center for Animal Healthy Environment, Beijing, People's Republic of China Department of Gastroenterology, Hangzhou First People’s Hospital, Nanjing Medical University, Hangzhou, China Jilin Ginseng Academy Changchun University of Chinese Medicine Changchun 130117 China Department of Pharmacology State‐Province Key Laboratories of Biomedicine‐Pharmaceutics of China Key Laboratory of Cardiovascular Research Ministry of Education Harbin Medical University Harbin Heilongjiang Province China School of Basic Medical Sciences Xi'an Jiaotong University China School of Food and Biological Engineering Jiangsu University Zhenjiang China Engineering Research Center for the Development and Application of Ethnic Medicine and TCM (Ministry of Education), Guizhou Medical University, Guizhou, People’s Republic of China; School of Pharmacy, Guizhou Medical University, Guizhou, People’s Republic of China State Key Laboratory of ASIC and System, School of Microelectronics, Fudan University, Shanghai 200433, People’s Republic of China Department of Thoracic Surgery, Ningbo First Hospital , Ningbo , 315010, Zhengjiang , China Department of Medical Microbiology and ImmunologySchool of MedicineCreighton University Omaha Nebraska USA Division of Immunology and Genetics, The John Curtin School of Medical Research, The Australian National University (ANU), PO Box 334, Canberra, ACT 2601, Australia College of Forestry, Shanxi Agricultural University , Taigu, Shanxi 030801 , P.R. China Discipline Consulting Service, National Science Library, Chinese Academy of Sciences, Beijing 100190, China. Department of Library, Information and Archives Management, University of Chinese Academy of Sciences, Beijing 100190, China. Department of General Surgery, Shenzhen Hospital of Armed Police Frontier CorpsShenzhen 518029, China. Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin of Xinjiang Production and Construction Corps & College of Life Science, Tarim University, Alar 843300, PR China School of Mechanical Engineering, Nanjing Institute of Technology, Nanjing 211167, China Laboratory of Advanced Materials, Fudan University, Shanghai 200438, P. R. China Department of Urology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, Hainan, China (mainland) Key Laboratory for Photonic and Electronic Bandgap Materials; Ministry of Education; School of Physics and Electronic Engineering; Harbin Normal University; Harbin 150025 Department of Medical Service Supervision, Qiqihar Health Inspection Bureau, Qiqihar, Heilongjiang, China Department of Clinical Pharmacology, Wuhan Medical & Healthcare Center for Women and Children, Hubei, China. *Department of Molecular Biosciences and Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Disease, Peking Union Medical College and Chinese Academy of Medical Sciences, Mentougou District, Beijing, China School of Civil and Environmental Engineering, Harbin Institute of Technology (Shenzhen), Shenzhen 518055, China; Engineering Management Center, Bureau of Public Works of Shenzhen Municipality, Shenzhen 518031, China Department of Radiology, the Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China. College of Horticulture, Sichuan Agricultural University, Chengdu 611130, China Harbin Institute of Technology Section of Pediatric Sleep Medicine, Department of Pediatrics, Comer Children's Hospital, Biological Sciences Division, The University of Chicago, Chicago, IL Department of Orthopedics, China-Japan Union Hospital of Jilin University, Changchun, China State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, China College of Chemistry and Molecular Sciences; Key Laboratory of Biomedical Polymers of Ministry of Education; Institute of Advanced Studies - 68756663; China Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University Department of Medical Biochemistry and Biophysics Karolinska Institute Stockholm Sweden Tribology Research Institute State Key Laboratory of Traction Power School of Mechanical Engineering Southwest Jiaotong University 610031 Chengdu China Department of Plastic Surgery, Peking Union Medical College Hospital Centre of Medical and Radiation Physics University of Wollongong Wollongong Australia; Icon Cancer Centre Guangzhou China Department of Materials Science, Fudan University, Shanghai 200433, P. R. China; International Institute for Intelligent Nanorobots and Nanosystems, Fudan University, Shanghai 200438, P. R. China Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging National-Regional Key Technology Engineering Laboratory for Medical Ultrasound School of Biomedical Engineering School of Medicine Shenzhen 518060 China; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry School of Chemistry Sun Yat-Sen University Guangzhou 510275 China Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States Department of Thoracic Surgery, Tongji University Affiliated Shanghai Pulmonary Hospital, Tongji University School of Medicine , Shanghai, China Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371 Robotics Engineering Department, Worcester Polytechnic Institute, Worcester, MA, USA State Key Laboratory of Infrared Physics, Shanghai Institute of Technical Physics, Chinese Academy of Sciences, 500 Yu Tian Road, Shanghai 200083, China Key Laboratory for Organic Electronics and Information Displays, Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics , , 100101, Beijing, China; Chinese Academy of Sciences , , 100101, Beijing, China Section of Sleep Medicine, Department of Pediatrics, University of Chicago, Chicago, IL 60637, U.S.A. The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; The Science Center for Future Foods, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China State Key Laboratory of Marine Resource Utilization in South China Sea, School of Materials Science and Engineering, Hainan University, Haikou, 570228, P. R. China aFrom the Department of Pathology, The University of Chicago, Chicago, Illinois 60637 College of Material, Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou 311121, China Department of Automation, Xiamen University , Xiamen, Fujian 361102, China School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, Nanjing University, Nanjing 210093, China Lundberg‐Kienlen Lung Biology and Toxicology Laboratory, Department of Physiological SciencesOklahoma State University Stillwater Oklahoma USA Department of Endocrinology, First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, P.R. China Institute of Integrative Medicine and State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences No. 5625, Renmin Street Changchun 130022 China; University of Science and Technology of China Hefei Anhui 230039 China Teaching and Research Unit of Hygienic Toxicology of Chongqing University of Medical Sciences Chongqing 400016 China Rehabilitation Medicine Center and Institute of Rehabilitation Medicine, West China Hospital Sichuan University Chengdu PR China; Key Laboratory of Rehabilitation Medicine in Sichuan Province Sichuan University Chengdu PR China Department of Chemistry, Boston College, 2609 Beacon Street, Chestnut Hill, Massachusetts02467, United States Department of Cardiology, First Affiliated Hospital of Medical School, Xi’an Jiaotong University; Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an Medical Research & Biometrics Center, National Center for Cardiovascular Diseases, Beijing, China Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska Department of Emergency, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, No. 1665 Kongjiang Road, Shanghai 200092, China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University Department of Oral and Maxillofacial Surgery, the Second Hospital of Shandong University; Research Center of 3D Printing in Stomatology of Shandong University, Jinan Department of Immunology Tianjin Medical University Cancer Institute and Hospital Tianjin China Medical Research & Biometrics Center, Cardiovascular Institute and Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Department of Chemistry, School of Science, Shanghai University Laboratory of Micro-Nano Optoelectronic Materials and Devices, Key Laboratory of Materials for High-Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800, China; Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Science, Beijing 100080, China Nanlou Respiratory Diseases Department The Chinese People's Liberation Army (PLA) General Hospital Beijing 100853 People's Republic of China Department of Emergency, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200082, P.R. China Department of Bone Marrow Transplantation Hebei Yanda Lu Daopei Hospital Langfang China Section of Pediatric Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, Biological Sciences Division, The University of Chicago, Chicago, Illinois; and Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607-7061, United States Department of Earth, Ocean, and Atmospheric Science, Florida State University and National High Magnetic Field Laboratory, Tallahassee, FL 32306; and State Key Laboratory for Mesoscopic Physics and Frontiers Science, Center for Nano-Optoelectronics, School of Physics, Peking University 1 , Beijing 100871, China Kunshan Maternity and Children's Health Care Hospital Department of Otolaryngology Kunshan China Department of Plant Pathology, Nanjing Agriculture University, Nanjing, China; Key Laboratory of Integrated Management of Crop Diseases and Pests (Ministry of Education), Nanjing, China Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education, School of Energy & Environment, Southeast University, Nanjing, Jiangsu, 210096, China China University of Petroleum (East China) Qingdao China MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, Department of Chemical Engineering, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China Department of Anatomy, Fudan University, Shanghai, PR China Medical Research and Biometrics Center, National Center for Cardiovascular Diseases, Beijing, China (Y.W.). Institute of Medical Technology, Peking University Health Science Center, Beijing, China; Department of Radiology, Peking University Third Hospital, Beijing, China Authors' Affiliations: 1Immunomedics, Inc. and 2IBC Pharmaceuticals, Inc., Morris Plains, New Jersey; and 3Garden State Cancer Center, Center for Molecular Medicine and Immunology, Belleville, New Jersey Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, United States; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, United States Department of Physiology, Anhui Medical University, Hefei, Anhui 230032, China. Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China. National Center for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Cardiology, First Affiliated Hospital of Medical School, Xi’an Jiaotong University, Xi’an, Shaanxi, China (mainland) Research Institute of Urology, Lanzhou University Second Hospital, Lanzhou University, Lanzhou, Gansu 730030, China. Key Laboratory of Gansu Province for Research on Urinary System Diseases, Lanzhou University, Lanzhou, Gansu 730030, China. Gansu Provincial Center of Clinical Medicine for Urinary System Diseases, Lanzhou University, Lanzhou, Gansu 730030, China. Department of Urology, Yulin Second Hospital, Yulin, Shaanxi 719000, China. College of Pharmacy, Wannan Medical College, Wuhu, Anhui, China School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Key Laboratory of Advanced Ceramics and Machining Technology (Ministry of Education) Tianjin University Tianjin 300350 China; State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science and Engineering Hainan University Haikou 570228 China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety and Beijing Laboratory for Food Quality and Safety, Beijing, China Department of Microbiology, Molecular Medicine and Cancer Research Center, College of Basic Medical Sciences, Chongqing Medical University, Chongqing, China Contribution from the Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Department of Chemistry, Yale University, New Haven, Connecticut 06520, and Department of Chemical Engineering, Auburn University, Auburn, Alabama 36830 Department of Orthopaedics, Nanjing General Hospital, Nanjing 210000, China Department of Chemistry, Indiana University, 800 E Kirkwood Avenue, Bloomington, Indiana 47405, United States Department of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China; Shanghai Institute for Pediatric Research, Shanghai, China State Key Laboratory of Brain and Cognitive Science Institute of Psychology, Chinese Academy of Sciences Beijing China; Department of Psychology University of Chinese Academy of Sciences Beijing China Key Laboratory of Development and Evaluation of Chemical and Herbal Drugs for Animal Use, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People's Republic of China Department of Orthopedic Surgery Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Shanghai 200233 China Department of Neurosurgery, the First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi Province, China Yang Wang (), Johns Hopkins University, Baltimore, Maryland. Laboratory of Statistical Genetics and Epigenome, College of Animal Science and Technology Nanjing Agricultural University Nanjing China Department of Behavioural and Social Sciences The City University of Hong Kong Hong Kong SAR China Departamento de Química, C-9, Universidad Autónoma de Madrid, 28049 Madrid, Spain, and Department of Chemistry, Beijing Normal University, 100875 Beijing, China Key Laboratory of Photochemical Conversion and Optoelectronic Materials Technical Institute of Physics and Chemistry Chinese Academy of Science Beijing 100190 P. R. China Key Laboratory of Soft Chemistry and Functional Materials, Ministry of Education, Nanjing University of Science and Technology, Nanjing 210094, China State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, China Institute of Advanced Chemical Power Source; School of Chemical Engineering and Technology; Harbin Institute of Technology; Harbin; China Section of Pediatric Sleep Medicine, Department of Pediatrics, Comer Children’s Hospital, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois 60637 Department of Pathology Changhai Hospital Second Military Medical University Shanghai China Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital, Fudan University, Shanghai 200438, China Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin, China Section of Pediatric Sleep Medicine, Department of Pediatrics, Comer Children's Hospital, Pritzker School of Medicine, The University of Chicago, Chicago, IL Hefei National Laboratory for Physical Sciences at the Microscale Fujian Institute of Innovation of Chinese Academy of Sciences School of Chemistry and Materials Science University of Science and Technology of China Hefei, Anhui 230026 P. R. China Department of Pathophysiology, School of Basic Medical Science, Dalian Medical University, Dalian, China School of Grain Science and Technology Jiangsu University of Science and Technology Zhenjiang China Medical Research and Biometrics Center, Fu-Wai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China Kosair Children's Hospital Research Institute and Division of Pediatric Sleep Medicine, Department of Pediatrics, University of Louisville, Louisville, Kentucky Department of Physiology, Medical College of Shihezi University, Shihezi, Xinjiang 832002, P.R. China School of Software Engineering, University of Science and Technology of China, Hefei, Anhui 230026, China Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Social Medicine School of Public Health, China Medical University P.R. China Shanghai Anti-Doping Laboratory, Shanghai University of Sport, Shanghai 200438, China Dialysis Vascular Access Research Group Division of Nephrology Department of Medicine University of Cincinnati Cincinnati Ohio Department of Burns, The First Affiliated Hospital, Jiangxi Medical College, Nanchang 330006 Jiang xi Province, P.R. China. Department of Urology Hanzhong Central Hospital Hangzhong China Hubei Institute for Food and Drug Control, Wuhan 430064, PR China Angmedicine Research Center of Central South University, Changsha, Hunan 410008, China.; Xiangya Hospital of Central South University–Amcan Pharmaceutical Biotechnology Co. Ltd. Joint Research Center, Changsha, Hunan 410008, China.; Institute of Integrative Medicine, Xiangya Hospital, Central South University, Changsha, Hunan 410008, China. Department of Chemistry University of Illinois at Chicago 845 W. Taylor St., Rm. 4500 Chicago IL 60607 USA Institute for Advanced Materials (IAM), School of Physics and Telecommunication Engineering, South China Normal University, Higher Education Mega Center, Guangzhou 510006, China College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China Center of Interventional Oncology and Liver Diseases, Beijing You’an Hospital, Capital Medical University, Beijing, P.R. China; Department of Neonatology, the First Affiliated Hospital of Anhui Medical University, Hefei 230022, China College of Veterinary Medicine, China Agricultural University, Beijing, China Department of Obstetrics and Gynecology The First Affiliated Hospital of Xiamen University Xiamen University Xiamen China; Key Laboratory of Reproductive Health Research Fujian Province University School of Medicine Xiamen University Xiamen China Laboratory of Ethnopharmacology, Institute of Integrated Traditional Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, China Department of Chemotherapy, Cancer Center, Qilu Hospital of Shandong University, Jinan, Shandong 250012, P.R. China College of Horticulture, College of Life Sciences, FAFU-UCR Joint Center for Horticultural Biology and Metabolomics, Fujian Agriculture and Forestry University , Fuzhou 350002, China The Xi’an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, School of Basic Medicine, Xi’an Medical University, Xi’an 710021, China School of Mechanical Electrical and Vehicle Engineering, East China Jiaotong University, Nanchang 330013, China State Key Laboratory of Electronic Thin Film and Integrated Devices School of Physics University of Electronic Science and Technology of China Chengdu 610054 China College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China College of Veterinary Medicine, National Reference Laboratory of Veterinary Drug Residues (SCAU), South China Agricultural University, Guangzhou 510642, PR China Huawei Technologies Canada, ON, Canada Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China From the Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology; National Center of Stomatology; National Clinical Research Center for Oral Diseases; and National Engineering Laboratory for Digital and Material Technology of Stomatology. Beichen District Center for Disease Control and Prevention, Tianjin, China Materials Science and Engineering Program, University of California, San Diego, La Jolla, CA 92093, USA. Aix Marseille University, CNRS, Center Interdisciplinaire de Nanoscience de Marseille, UMR 7325, «Equipe Labellisée Ligue Contre le Cancer», Marseille 13288, France; Hubei Gedian Humanwell Pharmaceutical Co. Ltd., E-zhou 436070, P. R. China Teclison Ltd., Montclair, NJ; Renal Division, Department of Medicine, Heilongjiang Academy of Chinese Medicine Sciences, Harbin, Heilongjiang 150036, P.R. China 1Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Department of Gastroenterology Changzhou First People's Hospital Changzhou Changzhou Jiangsu Province China Department of Pharmaceutics, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854-8020 Civil Aviation Medicine Center of Civil Aviation Administration of P.R. China. Division of Stem Cell and Tissue Engineering, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, PR China. Yang.Wang@163.com The Education Ministry Key Laboratory of Resource Chemistry; Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee; Key Laboratory of Molecular Imaging Probes and Sensors; Department of Chemistry, Shanghai Normal University; Shanghai 200234 MassBiologics of the University of Massachusetts Chan Medical School Academy of National Food and Strategic Reserves Administration, Beijing 100037, China Psychology Institute, Inner Mongolia Normal University, Hohhot, Inner Mongolia, P.R. China; Early Intervention Unit, Department of Psychiatry, Affiliated Nanjing Brain Hospital, Nanjing Medical University, Nanjing, P.R. China; Functional Brain Imaging Institute, Nanjing Medical University, Nanjing, P.R. China Institute of Environment and Health, Tianjin Centers for Disease Control and Prevention Tianjin China Thoracic Surgery Department, Beijing Chao-Yang Hospital, Capital University of Medical Science, Beijing 100020, China. Graduate Program in Genetics, Tufts University Medical School State Key Laboratory of Infrared Physics Shanghai Institute of Technical Physics Chinese Academy of Sciences Shanghai 200083 China; State Key Laboratory of ASIC and System School of Microelectronics Fudan University Shanghai 200433 China The Key Laboratory of Synthetic and Biological Colloids Ministry of Education School of Chemical and Material Engineering Jiangnan University 1800 Lihu Road Wuxi 214122 P. R. China College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China Department of Plant Pathology, Nanjing Agricultural University, Nanjing 210095, China Medical Research & Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100037, China. Department of Chemical Biology and Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics; School of Pharmacy; Tianjin Medical University; Tianjin 300070; P. R. China Departments of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, P.R. China. Orthopedic Laboratory of Chongqing Medical University, Chongqing 40016, P. R. China; Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P. R. China Department of Mechanical and Aerospace Engineering, Rutgers University, New Brunswick, NJ 08903, USA State Key Laboratory of Supramolecular Structure and Materials, ‡Institute of Theoretical Chemistry, and §State Key Laboratory of Inorganic Synthesis & Preparative Chemistry, Jilin University, Changchun 130012, P. R. China Saint Louis University Department of Physics, , 3511 Laclede Ave., St. Louis, Missouri 63103 Department of Oncology, Chengdu 363 Hospital, Chengdu, Sichuan 610041, P.R. China Department of Physical Examination Center, The Affifiliated Lianyungang Hospital of Xuzhou Medical University, No. 182, Tongguan North Road, Lianyungang 222000, Jiangsu, China Department of Chemical Engineering Monash University Clayton Victoria 3800 Australia Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi 214063 Jiangsu China Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390 Engineering Research Center of Nano-Geomaterials of Ministry of Education, China University of Geosciences, Wuhan 430074, P. R. China Department of Anesthesiology, The 4th People’s Hospital of Guiyang, Guiyang, China Department of Ultrasound and Imaging, Yichang Yiling Hospital, Yichang city 443100, Hubei province, China Molecular Oncology Laboratory of Cancer Research Institute, The First Affiliated Hospital of China Medical University, Shenyang 110001, China Institute of Urology, Jiangxi Medical College, and Department of Neurosurgery, Second Affiliated Hospital of Jiangxi Medical College, Nanchang 330006, China. Life Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831; Department of Cancer Genetics, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263; Department of Molecular and Cellular Biochemistry and Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210; Division of Medical and Molecular Genetics, GKT School of Medicine, Guy's Hospital, London SE1 9RT, United Kingdom; and Department of Biochemistry and Biophysics, School of Medicine and Dentistry,... Department of Orthopaedics, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China Department of Gastroenterology, Institute of Digestive Diseases, Tongji Hospital Affliated to Tongji University, Shanghai 200065, China. The Experimental Research Laboratory, Division of Cardiology, University of Louisville, and Jewish Hospital Heart and Lung Institute, Louisville, KY 40292 Hubei Key Laboratory of Animal Nutrition and Feed Science, Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Wuhan Polytechnic University, China State Key Laboratory of Fine Chemicals, and Department of Pharmaceutical Science Dalian University of Technology 2 Linggong Road 116024 Dalian China School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China Chinese Academy of Sciences; University of Chinese Academy of Sciences College of Pharmacy Shandong University of Traditional Chinese Medicine Jinan P. R. China School of Chemical Engineering, Nanjing University of Science and Technology, 210094, China Institute of Integrative Medicine Department of Integrated Traditional Chinese and Western Medicine Xiangya Hospital Central South University Changsha Changsha 410008 China Department of Pathology, Shenzhen People's Hospital, Second Clinical Medical College of Jinan University, Shenzhen, Guangdong 518020, P.R. China Yang Wang, Johns Hopkins University. Institute of Urology, Jiangxi Medical College, Nanchang 330006, China. wangy63cn@sina.com Department of Earth, Ocean and Atmospheric Science, Florida State University, and National High Magnetic Field Laboratory, Tallahassee, FL 32306, USA. Department of Acupuncture, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China Alkali Soil Natural Environmental Science Center, Northeast Forestry University/Key Laboratory of Saline-alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education HarbinChina State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science, Fudan University, Shanghai 200433, P. R. China Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, 214122, China Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Beijing Normal University Institute of Theoretical Chemistry, Jilin University, Changchun 130023, People’s Republic of China Betta Pharmaceuticals Co., Ltd Hangzhou China Institute of Rocket Force Medicine State Key Laboratory of Trauma, Burns and Combined Injury Third Military Medical University Chongqing 400038 China Institute of Modern Physics; Chinese Academy of Sciences; Lanzhou 730000; China; School of Nuclear Science and Technology Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, National Center for Biodefense and Infectious Diseases, George Mason University, Manassas, Virginia 20110, and Department of Radiation Medicine, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, D.C. 20007 School of Public Health and Management, Research Center for Medicine and Social Development, The Innovation Center for Social Risk Government in Health Key Laboratory of Molecular Pathogen and Immunology of Animal of Luoyang College of Animal Science and Technology Henan University of Science and Technology Luoyang China Department of Urology, Wuxi People’s Hospital Affiliated Nanjing Medical University , Wuxi, Jiangsu , China Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, 300060 Tianjin, China; National Clinical Research Center of Cancer, 300060 Tianjin, China; Key Laboratory of Cancer Immunology and Biotherapy, 300060 Tianjin, China State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, P. R. China. The Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering Jiangnan University 1800 Lihu Road Wuxi 214122 China Center for Biomaterials and Biopathways, Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang 310027, China School of Pharmacy, Anhui Medical University, Hefei, People’s Republic of China; Key Laboratory of major autoimmune disease, Anhui Province, School of Pharmacy, Anhui Medical University, Hefei, People’s Republic of China; The Key Laboratory of Anti-inflammatory and Immune medicines, Ministry of Education, Anhui Medical University, Hefei, People’s Republic of China School of Electronic Information Engineering, Changchun University of Science and Technology, Changchun 130022, China Department of Pathology,University of Pittsburgh,Pittsburgh,PA; Department of Hepatobiliary Surgery,Peking University People's Hospital,Beijing,China State Key Laboratory of Supramolecular Structure and Materials Institute of Theoretical Chemistry Jilin University Qianjin Avenue 2699 Changchun 130012 China State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, 38 Xueyuan Road, Beijing 100191, China Britton Chance Center for Biomedical Photonics Wuhan National Laboratory for Optoelectronics‐Huazhong University of Science and Technology Wuhan China; MoE Key Laboratory for Biomedical Photonics, Collaborative Innovation Center for Biomedical Engineering, School of Engineering Sciences Huazhong University of Science and Technology Wuhan China Department of Breast and Thyroid, Jining No. 1 People’s Hospital, Jining, Shandong Province, People’s Republic of China Janssen R&D LLC, 1400 McKean Road, Spring House, PA 19477, USA Emergency Trauma CenterThe First Affiliated Hospital of Nanchang University Nanchang China Wenjiang District People’s Hospital, Chengdu, China Department of Oncology, Nanjing Medical University, Nanjing, China Shandong Institute of Parasitic Diseases Shandong First Medical University & Shandong Academy of Medical Sciences Jining China Department of Respiratory & Critical Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China Biotechnology Research Center Chongqing Key Laboratory of Plant Resource Conservation and Germplasm Innovation Southwest University Chongqing China Guangdong University of Finance, Guangzhou, China Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China; National Clinical Research Center for Skin and Immune Diseases, Beijing, China; NMPA Key Laboratory for Quality Control and Evaluation of Cosmetics, Beijing, China Department of Pharmacology, Lineberger Comprehensive Cancer Center University of North Carolina Chapel Hill North Carolina USA School of Pharmacy, Tianjin University of Traditional Chinese Medicine, Tianjin, China Department of Pathology and Key Laboratory for Xinjiang Endemic and Ethnic Diseases, The First Affiliated Hospital, Shihezi University School of Medicine Shihezi 832002, China. Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of education, West China School of Pharmacy, and State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu, China Department of Chemistry, University of Illinois, Urbana, IL 61801; School of Material Science and Engineering, Jiangsu University, Zhenjiang 212013, China Department of Gynecology and Obstetrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, P.R. China The Affiliated Drum Tower Hospital of Nanjing University Medical SchoolNanjing, China Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA Materials Science and Engineering Program University of California San Diego La Jolla CA 92093 USA State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, College of Veterinary Medicine, Lanzhou University, Lanzhou 730000, P. R. China State Key Laboratory of Applied Organic Chemistry; Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province; College of Chemistry and Chemical Engineering; College of Resources and Environment; Institute of Biochemical Engineering & Environmental Technology First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China; Tianjin Key Laboratory of Translational Research of TCM Prescription and Syndrome, Tianjin 300193, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300193, China Key Laboratory of Green Printing, Institute of Chemistry Chinese Academy of Sciences 100190 Beijing P. R. China Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA Department of Pediatrics, Section of Pediatric Sleep Medicine, Pritzker School of Medicine, The University of Chicago, Chicago, IL Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), the Second Department of Thoracic Oncology, Peking University Cancer Hospital and Institute, Beijing 100142, China. Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin 300072, China Department of Orthopedics China‐Japan Union Hospital of Jilin University Changchun China Department of Sonography Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences Beijing China Department of Materials Science and Engineering; Hefei University of Technology; Hefei; China Bio-X Center, Key Laboratory for the Genetics of Developmental & Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, PR China.; Institutes of Biomedical Sciences, Fudan University, 138 Yixueyuan Road, Shanghai 200032, PR China; Institute for Nutritional Sciences, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, 320 Yueyang Road, Shanghai 200031, PR China *Department of Pathology and Committee on Immunology, University of Chicago, Chicago, IL 60637; Department of Breast Surgery Qilu Hospital Shandong University Ji'nan Shandong China College of Pharmacy Xinxiang Medical University Xinxiang China Department of Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China. State Key Laboratory for Mesoscopic Physics, School of Physics, Peking University, Beijing 100871, China Department of Spine Surgery, Ningbo No. 6 Hospital, Ningbo, China Fudan University, Shanghai 200433, China Department of Hand Surgery, Beijing Jishuitan Hospital, Peking University Fourth School of Clinical Medicine, Beijing 100035, China Dexing Hospital of Traditional Chinese Medicine, Dexing, Jiangxi 334200, P.R. China The Lundberg-Kienlen Lung Biology and Toxicology Laboratory, Department of Physiological Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, Oklahoma; State Key Laboratory of Cardiovascular Disease Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China School of Mechatronics Engineering, Harbin Institute of Technology, Harbin 150001, China Beijing Key Laboratory of Nasal diseases, Beijing Institute of Otolaryngology, Beijing 100005, China. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P.R. China, Département de Chimie, CINaM CNRS UPR 3118, 13288 Marseille, France, Molecular Simulation Engineering Laboratory, DI3, University of Trieste, 34127 Trieste, Italy, Spectropole, Faculté de Saint-Jérôme, Marseille, France, and Laboratoire de Chimie Bactérienne, CNRS UPR 9043, 13402 Marseille, France National Key Laboratory for Crop Genetics and Germplasm Enhancement, Jiangsu Plant Gene Engineering Research Center, Nanjing Agricultural University, Nanjing 210095, China School of Pharmacy Shenyang Pharmaceutical University Shenyang China Key Laboratory of Agricultural Biodiversity and Pest Control, College of Plant Protection, Yunnan Agricultural University , Yunnan 650201 , Kunming , China Department of Mechanical Engineering, University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080, United States Department of Entomology and MOA Key Lab of Pest Monitoring and Green Management, College of Plant Protection China Agricultural University Beijing China State Key Laboratory of Structural Chemistry; Fujian Institute of Research on the Structure of Matter; Chinese Academy of Sciences; Fuzhou; China Key Laboratory of Medical Molecular Virology,Ministry of Education and Health, School of Basic Medical Sciences, Shanghai Medical College, Fudan University,Shanghai,China College of Materials, Fujian Key Laboratory of Advanced Materials, Xiamen Key Laboratory of Electronic Ceramic Materials and Devices, Xiamen University, Xiamen 361005, China School of Chemistry and Chemical Engineering, State Key laboratory of Coordination Chemistry, Nanjing University, Nanjing 210093, China Zhejiang Fisheries Technology Extension Center, Hangzhou, China School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, China Department of Physiology, Basic Medical Faculty of China Medical University, Shenyang 110001, China. State Key Laboratory of Infrared Physics Shanghai Institute of Technical Physics Chinese Academy of Sciences 500 Yutian Road Shanghai 200083 China National Key Laboratory for Germplasm Innovation & Utilization of Horticultural Crops, College of Horticulture and Forestry Sciences Huazhong Agricultural University Wuhan 430070 China State Key Lab of Respiratory Disease, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People’s Republic of China The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer (IBMC) Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China; School of Biology and Biological Engineering, South China University of Technology, Guangzhou, Guangdong 510006, China Department of Plastic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China Department of General Surgery, Huaihe Hospital of Henan University, Kaifeng, Henan, China; Institute of Evidence-Based Medicine and knowledge translation, Henan University, Kaifeng, Henan, China Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 Department of Chemical Engineering, University of Pittsburgh, Pittsburgh Pennsylvania 15261, Department of Chemistry, Yale University, New Haven, Connecticut 06520, Department of Chemical and Biomolecular Engineering, Clemson University, Clemson, South Carolina 29634, and National Energy Technology Laboratory, Pittsburgh Pennsylvania 15236 Laboratory of Advanced Materials, Department of Chemistry, Collaborative Innovation Center of Chemistry for Energy Materials, Fudan University, Shanghai 200433, China Department of Joint Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi Xinjiang, 830054, P. R. China. Key Laboratory for Organic Electronics and Information Displays (KLOEID) & Institute of Advanced Materials (IAM); Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM); Nanjing University of Posts & Telecommunications; Nanjing 210023; China Department of Orthopaedics, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangdong Pharmaceutical University; No. 19 Nonglinxia Road, Yuexiu District, Guangzhou, Guangdong Province, China State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China; University of the Chinese Academy of Sciences, Beijing 100049, PR China Department of Emergency; Changhai Hospital; Second Military Medical University; Shanghai 200433; China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China; Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety and Beijing Laboratory for Food Quality and Safety, Beijing, China Key Laboratory of Biology and Genetic Improvement of Horticultural Crops, Ministry of Agriculture and Rural Affairs; Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences , Beijing, 100081, China Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College of Fudan University, Shanghai, China State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing 211800, China School of Environment, Henan Normal University, Key Laboratory for Yellow River and Huai River Water Environmental and Pollution Control, Ministry of Education, Henan Key Laboratory for Environmental Pollution Control, Xinxiang, Henan 453007, PR China Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Medicine School of Shihezi University, Shihezi, Xinjiang, China (mainland) Beijing Advanced Innovation Center for Food Nutrition and Human Health College of Veterinary Medicine China Agricultural University Beijing China State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, PR China Shanghai Institute of Hematology, Ruijin Hospital of Shanghai Second Medical University, Shanghai,200025 P.R. China. zhugangw@shsmu.edu.cn Department of Ultrasound, PLA General Hospital, Beijing 100853, China. wangyang301@hotmail.com Department of Mechanical Engineering University of Texas at Dallas Richardson TX 75080 USA The Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, International Joint Research Laboratory for Nano Energy Composites, Jiangnan University, Wuxi 214122, P. R. China Department of Cardiovascular Surgery, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang 110016, China Department of Urology, Hainan General Hospital, Haikou, Hainan, China Department of Nuclear Medicine, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China Key Laboratory of Development and Evaluation of the Chemical and Herbal Drugs for Animal Use, College of Veterinary Medicine, National Center for Veterinary Drug Safety Evaluation, China Agricultural University, Beijing, China. State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, Qianjin Street 2699, Changchun 130012, China Department of General Surgery, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China Department of Tumor Institute, Yunnan Cancer Hospital, Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China Wuhan Research Institute of Materials Protection, Wuhan 430030, China Research Department, Childrens Hospital of Chongqing Medical University, Chongqing 401147, China Department of Neurosurgery Ningbo First Hospital Ningbo China From the Cardiovascular Department, First Affiliated Hospital of Medical College Xi’an Jiaotong University Xi’an China Department of Obstetrics and Gynecology The First Affiliated Hospital of Soochow University Soochow Jiangsu China; Department of Obstetrics and Gynecology The Affiliated Suqian Hospital of Xuzhou Medical University Suqian Jiangsu China Department of Clinical Pharmacology Xiangya Hospital Central South University Changsha P. R. China; Hunan Key Laboratory of Pharmacogenetics Institute of Clinical Pharmacology Central South University Changsha P. R. China; Engineering Research Center of Applied Technology of Pharmacogenomics Ministry of Education Changsha P. R. China; National Clinical Research Center for Geriatric Disorders Changsha P. R. China Department of Neurosurgery, the First Affiliated Hospital of Nanchang University, Nanchang 330008, Jiangxi, P. R. China Wenzhou Institute, University of Chinese Academy of Sciences; Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang325001, China Department of Biochemistry & Molecular Biology, Research School of Biology, College of Medicine, Biology and the Environment, Australian National University, Canberra, ACT, Australia *Division of Gastroenterology, GRASP Digestive Disease Center, Tufts–New England Medical Center, Boston, MA 02111; and Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200011, China Department of Applied Physics Hong Kong Polytechnic University Hong Kong 999077 China 1 National Centre for Veterinary Drug Safety Evaluation, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China State Key Laboratory of Ultrasound in Medicine and Engineering, College of Biomedical Engineering, Chongqing Medical University, Chongqing Key Laboratory of Biomedical Engineering Chongqing Medical University Chongqing China Coalbed Methane Resources and Reservoir Formation Process Key Laboratory of Ministry of Education, China University of Mining & Technology, Xuzhou, Jiangsu 221008, China Faculty of Psychology, Tianjin Normal University, Tianjin 300387, China; Key Research Base of Humanities and Social Sciences of the Ministry of Education, Academy of Psychology and Behavior, Tianjin Normal University, Tianjin 300387, China Tianjin Key Lab of Aqua-Ecology and Aquaculture, College of Fisheries, Tianjin Agricultural University, Tianjin 300384, China Key Laboratory of Materials Physics , Institute of Solid State Physics, Chinese Academy of Sciences, Hefei 230031, People’s Republic of China *Department of Pathology and Committee on Immunology, and Reproductive Centre, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China Department of Hand and Foot Surgery, Shandong Provincial Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China; Department of Hand and Foot Surgery, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China Department of Ultrasound Chinese PLA General Hospital Beijing China Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu, Sichuan 610041, China Key Laboratory of Animal Epidemiology of Ministry of Agriculture and Rural Affairs, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China Department of Cardiology, First Affiliated Hospital of Medical School, Xi’an Jiaotong University, Key Laboratory of Molecular Cardiology of Shaanxi Province, Key Laboratory of Environment and Genes Related to Diseases (Xi’an Jiaotong University), Ministry of Education, Shaanxi, China Institute for Materials Research Tohoku University 2‐1‐1 Katahira Aoba‐ku Sendai 980‐8577 Japan; Department of Mechanical System Engineering Graduate School of Engineering Tohoku University 6‐6‐01 Aoba, Aramaki Aoba‐ku Sendai 980‐8579 Japan Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition Shanghai Institute for Pediatric Research Shanghai P.R. China Laboratory of Aging Research and Cancer Drug Target, State Key Laboratory of Biotherapy, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China Department of Intensive Care Unit, Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine, Hangzhou, China; and Alkali Soil Natural Environmental Science Center Northeast Forestry University, Key Laboratory of Saline‐alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education Harbin Heilongjiang China Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences,Shanghai Medical College of Fudan University,Shanghai,China State Key Laboratory of Electronic Thin Flims and Intergrated Devices, School of Optoelectronic Information, University of Electronic Science and Technology of China (UESTC), 610054 Chengdu, Sichuan, P. R. China Department of Oncology, 363 Hospital, Chengdu, Sichuan 610041, P.R. China The Obstetrics & Gynecology Hospital of Fudan University, State Key Laboratory of Genetic Engineering, Fudan University , Shanghai 200090 , China Department of Thoracic Surgery The First People's Hospital of Yunnan Province Kunming City Yunnan Province China Department of Plastic Surgery, the First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310003, China. Beijing Advanced Innovation Center for Genomics, Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China;, , ,; Key Laboratory of Assisted Reproduction, Ministry of Education, Beijing 100191, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing 100191, China China Center for Type Culture Collection (CCTCC), College of Life Sciences, Wuhan University, Wuhan 430072, PR China Entomology and Plant Pathology, 127 Noble Research Center, Oklahoma State University, Stillwater, OK 74078 Institute of Microsurgery on Extremities Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University 600 Yishan Road Shanghai 200233 China School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui, China MOE Key Laboratory of Material Physics and Chemistry under Extrodinary Conditions, School of Science, Northwestern Polytechnical University, Xi’an 710129, China Department of Biology, Illinois Institute of Technology, 3101 South Dearborn Street, Chicago, Illinois 60616, United States Department of Pharmacological and Pharmaceutical Sciences University of Houston Houston TX USA Infection and Immunity Group and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China. Department of General Surgery, General Surgery Institute of Yangzhou, Northern Jiangsu People’s Hospital, Clinical Medical College, Yangzhou University, Yangzhou 225009, China; Department of General Surgery, Northern Jiangsu People’s Hospital, Yangzhou 225001, China; General Surgery Institute of Yangzhou, Yangzhou University, Yangzhou 225009, China; Yangzhou Key Laboratory of Basic and Clinical Transformation of Digestive and Metabolic Diseases, Yangzhou 225001, China Department of Urology The Fifth People's Hospital of Shanghai, Fudan University Shanghai China State Key Laboratory of Supramolecular Structure and Materials, Institute of Theoretical Chemistry Jilin University Qianjin Avenue 2699 Changchun 130012 P.R. China Academy of State Administration of Grain, Beijing, PR China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University , Beijing 100094 , China Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun 130117, China Department of Cardiology, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China The Key Laboratory of Carbohydrate Chemistry and Biotechnology Ministry of Education, School of Biotechnology Jiangnan University Wuxi China; The Key Laboratory of Industrial Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi China Department of Chemistry and Simon Fraser University, Burnaby, British Columbia, Canada College of Life Science, Liaoning Normal University, Dalian, Liaoning 116029, P.R. China Plastic Surgery Beijing Key Laboratory of Detection Technology for Animal Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for TCM Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai 201203, People’s Republic of China; Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang 110016, People’s Republic of China Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky; and; Department of Pediatrics, University of Chicago, Chicago, Illinois School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 China Hubei Key Laboratory of Animal Nutrition and Feed Science, Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Wuhan Polytechnic University, Wuhan, China Institute of Microsurgery on Extremities Shanghai Jiaotong University Affiliated Sixth People's Hospital Shanghai 200233 China Department of Infectious Diseases, The First Hospital, Jilin University, Changchun, Jilin, China; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, OK. Departments of Pathology and Internal Medicine, Washington University School of Medicine, St. Louis, Missouri 63110 Paul C. Lauterbur Research Center for Biomedical Imaging; Shenzhen Institutes of Advanced Technology; Chinese Academy of Sciences; Shenzhen 518055; China Department of Oral Pathology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, P. R. China. Shanghai Key Laboratory of Stomatology Shanghai, P. R. China. Department of Dermatology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Centre, Xi'an, Shaanxi 710061, P.R. China Beijing National Laboratory for Molecular Sciences and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, China, and Organometallic Chemistry Laboratory, RIKEN Advanced Science Institute, Hirosawa 2-1, Wako, Saitama 351-0198, Japan Research Center for High Altitude Medicine, Qinghai University, Xining, Qinghai 810016, China Computer and Information Science, Purdue University School of Science, 723 W. Michigan St SL280, Indianapolis, IN 46202, USA. Key Laboratory of Development and Evaluation of Chemical and Herbal Drugs for Animal Use, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China Department of Ultrasound, Chinese People's Liberation Army General Hospital, Beijing, China National Laboratory of Solid State Microstructures College of Engineering and Applied Sciences Jiangsu Key Laboratory of Artificial Functional Materials Key Laboratory of Intelligent Optical Sensing and Manipulation Ministry of Education Nanjing University Nanjing 210093 P. R. China Department of Pediatrics, Comer Children's Hospital, Biological Sciences Division, Pritzker School of Medicine, The University of Chicago, Chicago, Illinois School of Materials Science and Engineering, University of Science & Technology Beijing, Beijing, 100083, People's Republic of China School of Chemistry and Chemical Engineering; Harbin Institute of Technology; Harbin 150001; China Department of Chemistry, Boston College, Chestnut Hill, Massachusetts 02467, USA The Key Laboratory of Dairy Science of Education Ministry, Northeast Agricultural University, Harbin, 150030, China Section of Pediatric Sleep Medicine, Department of Pediatrics, Pritzker School of Medicine, Biological Sciences Division, The University of Chicago, Chicago, IL Department of Respiratory Medicine, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China. yangwang@fmmu.edu.cn College of Materials Science and Opto-electronic Technology University of Chinese Academy of Sciences Yanqi Lake, Huairou District Beijing 101408 P. R. China Lundberg-Kienlen Lung Biology and Toxicology Laboratory, Department of Physiological Sciences, Oklahoma State University, Stillwater, Oklahoma Key Laboratory of Saline-Alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, College of Life Sciences, Northeast Forestry University, Harbin 150040, China Department of CyberKnife Center, Huashan Hospital, Fudan University , No. 525, Hongfeng Road, Pudong District , Shanghai 200040 , China Division of Oncology, Nanjing Medical University, Nanjing 210000, China Guangdong Key Laboratory of Non-Human Primate Research, Laboratory of CNS Regeneration (Ministry of Education), Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou 510632, China Department of Medical Imaging, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, People’s Republic of China Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Department of Respiratory Medicine Peking University Cancer Hospital & Institute Beijing China State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, The Innovation Academy of Seed Design, Chinese Academy of Sciences, Wuhan, China; University of Chinese Academy of Sciences, Beijing, China Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China Department of Ultrasound, Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing, China Key Laboratory of Animal Physiology, Biochemistry and Molecular Biology of Hebei Province, College of Life Sciences, Hebei Normal University , Shijiazhuang 050024 , China State Key Laboratory for Mesoscopic Physics and Frontiers Science Center for Nano-optoelectronics, School of Physics, Peking University, Beijing 100871, China Department of Neurosurgery, Beijing Chaoyang Hospital Capital Medical University Beijing China *Pathology and; Department of State Key Laboratory of Freshwater Ecology and Biotechnology , Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China School of Public Health and Management; Chongqing Medical University; Chongqing China; Research Center for Medicine and Social Development; Chongqing Medical University; Chongqing China; The Innovation Center for Social Risk Governance in Health; Chongqing Medical University; Chongqing China Hubei Institute for Food and Drug Control, Wuhan, China Department of Neurosurgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China State Key Laboratory of Oral Diseases and National Clinical Research Center for Oral Diseases and Department of Oral Radiology, West China Hospital of Stomatology, Sichuan University, Chengdu, China †Department of Pathology, University of Chicago, Chicago, IL 60637; and Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston , MA 02215, USA; Department of Genetics, Harvard Medical School , Boston, MA 02115, USA Xidian University Department of Nephrology PLA 309th Hospital (General Hospital of PLA General Staff Department) Beijing China BGI‐Qingdao, BGI‐Shenzhen Qingdao China Department of Ultrasound China‐Japan Union Hospital of Jilin University Changchun Jilin China Center for Biomaterials and Biopathways; Department of Chemistry; Zhejiang University; Hangzhou 310027; P. R. China *Department of Pathology, University of Chicago, Chicago, IL 60637; and Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University Logistics Management Center of Huangpu Customs, Guangzhou 510700, China Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China (mainland) Department of Traditional and Western Medical Hepatology Third Hospital of Hebei Medical University Shijiazhuang China Department of Laboratory Medicine, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China Key Laboratory of Animal Antimicrobial Resistance Surveillance, MARA, College of Veterinary Medicine, China Agricultural University, Beijing, China School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China Department of Cardiovascular Surgery, The First Affiliated Hospital of University of Science and Technology of China, Hefei, China Laboratory of Synthesis and Natural Products Institute of Chemical Sciences and Engineering Ecole Polytechnique Fédérale de Lausanne EPFL-SB-ISIC-LSPN, BCH 5304 1015 Lausanne Switzerland Departments of Internal Medicine and Pathology, Howard Hughes Medical Institute, and Center for Immunology, Washington University School of Medicine, St. Louis, MO 63110; Searle Discovery, Monsanto, 700 Chesterfield Village Parkway North, St. Louis, MO 63198; and Department of Pathology, University of Chicago, Chicago, IL 60637 Department of Gastrointestinal Surgery, Tangshan Central Hospital, Tangshan, China Department of Physics, University of California at Berkeley, Berkeley, CA 94720, USA.; Materials Science Division, Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA 94720, USA. Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing 100083, China Departamento de Química C-13, Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain Department of Hepatobiliary Surgery Xian Yang Central Hospital Xian Yang Shaanxi China Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan 430072, China Department of Chemistry; School of Fundamental Sciences; China Medical University; Shenyang 110122; China Institution of Cardiac Surgery, Department of Cardiovascular Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China Department of Neurology, Ruijin Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China; Current address: Department of Neurology, Central Hospital of Wuhan, Wuhan 430000, China College of Environmental Science and Engineering, Hunan University, Changsha, Hunan 410082, China and Key Laboratory of Environmental Biology and Pollution Control (Hunan University), Ministry of Education, Changsha, Hunan 410082, China Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital Capital Medical University Beijing China; Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otolaryngology Beijing China Institute of Microsurgery on Extremities; Shanghai Jiao Tong University; Affiliated Sixth People's Hospital; Shanghai 200233; China Department of Mechanical Engineering, City University of Hong Kong, Hong Kong 999077, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China; Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China Department of Physics, University of California Berkeley, Berkeley, California 94720, United States MOE Key Laboratory of Bioinorganic and Synthetic Chemistry School of Chemistry Sun Yat-Sen University Guangzhou 510275 China School of Food and Biological Engineering, Hefei University of Technology, Hefei, P.R. China; Engineering Research Center of Bio-process, Ministry of Education, Hefei University of Technology, P.R. Hefei, China College of Civil Engineering, Xiangtan University, Xiangtan 411105, China Acupuncture Department, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing 100053, China Key Laboratory of Photochemical Conversion and Optoelectronic Materials; Technical Institute of Physics and Chemistry; Chinese Academy of Sciences; Beijing 100190; P. R. China Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China School of Psychology, Center for Studies of Social Psychology, Central China Normal University, Wuhan, China School of Environmental and Chemical Engineering, Shanghai Institute of Technology, Shanghai 201418, PR China Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, People’s Republic of China, and Department of Molecular Biology, Beijing Institute of Transfusion Medicine, Beijing 100850, People’s Republic of China Pain and Translational Symptom Science, University of Maryland School of Nursing, Baltimore, MD, USA; Center to Advance Chronic Pain Research, University of Maryland, Baltimore, MD, USA College of Biotechnology, Guilin Medical University, Guilin, Guangxi 541100, P.R. China First Affiliated Hospital of Nanchang University, Nanchang, China State Key Laboratory of Crop Stress Biology for Arid Areas, College of Plant Protection Northwest A&F University Yangling China State Key Laboratory of Rolling and Automation, Shenyang 110819, China Department of Biochemistry and Molecular Biology, Third Military Medical University, Chongqing 400038, China Departments of Surgery and Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100107, China College of Chemistry and Chemical Engineering; Central South University; Changsha 410083; China School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, Henan 450001, People’s Republic of China. Guangdong Key Laboratory of Mental Health and Cognitive Science/Center for Studies of Psychological Application/School of Psychology, South China Normal University, Guangzhou, China Department of Neurosurgery Huashan Hospital Fudan University Shanghai China Beijing Advanced Innovation Centre for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University Department of Hepatobiliary Surgery, Peking University People's Hospital, Beijing, China; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Chongqing Engineering Research Center for Nanomedicine, Department of Preventive Medicine, Third Military Medical University, Chongqing 400038, China Contribution from the Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802 Medical Research and Biometrics Center National Center for Cardiovascular Diseases Beijing China Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, P.R. China Department of Orthodontics, School and Hospital of Stomatology, Jilin University, Changchun 130021, China Department of Medicine and Department of Urology, Wuxi No. 2 People's Hospital Affiliated to Nanjing Medical University, Wuxi, Jiangsu 214002, China . Dialysis Vascular Access Research Group Division of Nephrology and Hypertension University of Cincinnati Cincinnati Ohio State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China School of Optical and Electronic Information and ‡Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, 1037 Luoyu Road, 430074 Wuhan, China School of Precision Instrument and Opto-Electronics Engineering, Tianjin University , Tianjin 300072, China Xi’an Institute of Optics and Precision Mechanics; University of Chinese Academy of Sciences School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Key Laboratory of Advanced Ceramics and Machining Technology of Ministry of Education Tianjin University Tianjin 300072 China School of Pharmacy, Anhui Medical University, Hefei 230032, China School of Public Health, Southeast University, Nanjing, PR China State Key Laboratory of Polymer Physics and Chemistry; Changchun Institute of Applied Chemistry; Chinese Academy of Sciences; Changchun; P. R. China Institute of Reproduction and Stem Cell Engineering, School of Basic Medical Science, Central South University, Changsha 410078, China. Gansu Center for Clinical Laboratory, Gansu Provincial Hospital, Lanzhou Department of reproductive medicine Xingtai People's Hospital Xingtai City Hebei Province China Department of Emergency Changhai Hospital, Second Military Medical University Shanghai China The Kidney Disease Research Center, Jingdong Yumei Kidney Disease Hospital, Beijing, China; Ningbo No. 6 Hospital, Ningbo, China Department of Prevention and Health Care, Hospital of Health Science Center (Y.W.), Peking University, Beijing. Department of Respiratory Medicine, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430014, P.R. China Department of Orthopaedic Surgery; Shanghai Sixth People's Hospital; Shanghai Jiao Tong University School of Medicine; Shanghai 200233; China From John Hunter Hospital/Hunter Medical Research Institute, New Lambton Heights, Australia (Y.W., C.R.L., N.S.); Centre for Clinical Epidemiology and Biostatistics, Royal Newcastle Hospital, Newcastle, New South Wales (J.R.A., C.A.D.); and Heart and Stroke Register, Centre for Clinical Epidemiology and Biostatics, Royal Newcastle Hospital, Newcastle, New South Wales (J.F.). Department of Pathophysiology, Wenzhou Medical University, Wenzhou, Zhejiang 325000, P.R. China Department of Radiology, Shandong Provincial Hospital Shandong University Jinan Shandong China College of Plant Protection Northwest A&F University Xianyang China School of Chemistry and Chemical Engineering, Southeast University, Nanjing 14122, PR China Department of histology and embryology Institute of neuroscience Wenzhou Medical University Wenzhou Zhejiang P. R. China School of Public Health, China Medical University Department of Radiology The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School Nanjing P.R. China State Key Laboratory of ASIC and System School of Microelectronics Fudan University Shanghai 200433 China; University of Chinese Academy of Sciences Beijing 100049 China Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Donghu Road-169, Wuhan, Hubei Province 430071, China Department of Chemistry, School of Food Engineering, Harbin University, Harbin 150086, P. R. China School of Nursing, Changchun University of Chinese Medicine , Changchun , China Dalian University of Technology Department of Biological and Chemical Sciences, Illinois Institute of Technology, 3101 South Dearborn Street, Chicago, Illinois 60616, United States Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otolaryngology Beijing China PerkinElmer Genomics Pittsburgh Pennsylvania Medical Laboratory, Yan'An Hospital, Kunming, Yunnan 650000, P.R. China Key Laboratory of Saline‐alkali Vegetation Ecology Restoration, Ministry of Education/Center for Bioactive Products Northeast Forestry University Harbin Heilongjiang China; Cao Pharmaceuticals Inc Webster Texas USA Department of Pathology, Shanghai Fourth People’s Hospital, Tongji University School of Medicine State Key Laboratory of Applied Organic Chemistry; Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province; College of Chemistry and Chemical Engineering; Institute of Biochemical Engineering and Environmental Technology; Lanzhou University Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Urumqi, China Institute of Orthopaedic Surgery, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai 200233; Institute of Urology, Nanchang University, Nanchang 330006 Department of Ultrasound, Shengjing Hospital of China Medical University, Shenyang 110000, China The Experimental Center of Functional Subjects, College of Basic Medical Scientific Research China Medical University Shenyang China Huazhong Agricultural University Key Laboratory of Horticultural Plant Biology (MOE), College of Horticulture and Forestry Sciences, , Wuhan 430070, China; Huazhong Agricultural University National R&D Center for Citrus Postharvest Technology, College of Horticulture and Forestry Sciences, , Wuhan 430070, China Medical Research & Biometrics Center, National Center for Cardiovascular Disease, Beijing, China School of Public Administration, Guangdong University of Finance, China Department of Cardiovascular Medicine The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China; Key Laboratory of Molecular Cardiology of Shaanxi Province Xi'an China; Key Laboratory of Environment and Genes Related to Diseases (Xi'an Jiaotong University) Ministry of Education Xi'an, Shaanxi China Nishina Center for Accelerator‐Based Science RIKEN Wako Japan Sichuan Integrative Medicine Hospital Chengdu China Division of Energy and Environment; Graduate School at Shenzhen; Tsinghua University; Shenzhen; China Department of Dermatology Beijing Children's Hospital National Center for Children's Health Capital Medical University Beijing China Department of Oral and Maxillofacial Surgery Peking University School and Hospital of Stomatology Beijing China Department of Medical Research and Biometrics Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolNanjing, China Huazhong University of Science and Technology Department of Materials Science and Engineering, Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG), Southern University of Science and Technology, No. 1088, Xueyuan Rd., Shenzhen 518055, Guangdong, China Wenzhou Institute University of Chinese Academy of Sciences Zhejiang Engineering Research Center for Tissue Repair Materials Wenzhou Zhejiang 325001 P. R. China Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100081, China Departments of Analytical Chemistry, Protein Engineering, and Pharmacokinetics and Metabolism, Genentech, Inc., South San Francisco, California 94080 Department of endocrinology, Nanjing Pukou Central Hospital, Nanjing, China Center of Interventional Oncology and Liver Diseases, Beijing You’an Hospital, Capital Medical University, Beijing, China; The Education Ministry Key Laboratory of Resource Chemistry, Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors, Department of Chemistry, Shanghai Normal University; Shanghai 200234; China Stomatology Hospital, School of Stomatology Zhejiang University School of Medicine Hangzhou Zhejiang China; Zhejiang Provincial Clinical Research Center for Oral Diseases Hangzhou Zhejiang China; Key Laboratory of Oral Biomedical Research of Zhejiang Province Cancer Center of Zhejiang University Hangzhou Zhejiang China Immunology Program, John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia Aix‐Marseille Université CNRS Centre Interdisciplinaire de Nanoscience de Marseille UMR 7325 Equipe Labellisée Ligue Contre le Cancer 13288 Marseille France The Institute of Chemical Physics, School of Chemistry, Beijing Institute of Technology, Beijing 100081, People’s Republic of China Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, P.R. China Wenzhou Key Laboratory of Perioperative Medicine, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, People’s Republic of China State Key Laboratory of Heavy Oil Processing, College of Chemical Engineering, China University of Petroleum, Qingdao 266580, China School of Physical Science and Technology, ShanghaiTech University, Shanghai 201210, China Division of Immunology and Genetics, John Curtin School of Medical Research, The Australian National University PO Box 334 Canberra ACT 2601 Australia Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan; Department of Mechanical Systems Engineering, Graduate School of Engineering, Tohoku University, 6-6-01 Aoba, Aramaki, Aoba-ku, Sendai 980-8579, Japan Department of Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, No.2 Yuanmingyuan West Road, Beijing 100193, P. R. China Department of Cell Biology and Physiology, and Cystic Fibrosis/Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Radiology, Medical College of Wisconsin, Milwaukee, WI, USA; Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. China Division of Immunology and Genetics, The John Curtin School of Medical Research, The Australian National University, Canberra ACT 2601, Australia Department of Anesthesiology, The Second Hospital of Dalian Medical University , No. 467 Zhongshan Road, Shahekou District , Dalian , Liaoning , China Immunomedics, Inc. Morris Plains, New Jersey. Department of Hepatobiliary Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China Department of Acupuncture, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange Street, Xicheng District, Beijing 100053, China Medical Research and Biometrics Center, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Aix Marseille Univ, CNRS, Center Interdisciplinaire de Nanoscience de Marseille, UMR 7325, Equipe Labellisée Ligue Contre le Cancer, Marseille, France; Hubei Gedian Humanwell Pharmaceutical Co. Ltd., E-zhou, P. R. China MassBiologics, Boston, Massachusetts02126, United States Department of Chemistry, University of Illinois at Urbana–Champaign, Urbana, IL 61801 Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Chaoyang, Beijing, China; and Fujian Provincial Key Laboratory of Reproductive Health Research, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, China Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan State Key Laboratory of Supramolecular Structure and Materials Jilin University Qianjin Avenue 2699 Changchun 130012 China Department of Pharmaceutical Analysis, School of Pharmacy, Fudan University State Key Laboratory of ASIC and System, School of Microelectronics, Fudan University, Shanghai 200433, China Department of Emergency, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Yangpu, Shanghai 200092, P.R. China Institute of Integrative Chinese Medicine, Xiangya Hospital, Central South University, Changsha 410008, P.R. China Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; Key Laboratory of Assisted Reproduction, Peking University, Ministry of Education, Beijing 100191, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing 100191, China Henan Key Laboratory of Photovoltaic Materials, School of Physics, Henan Normal University 1 , Xinxiang 453007, People’s Republic of China Rehabilitation Medical Center and Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, PR China; Key Laboratory of Rehabilitation Medicine in Sichuan Province, Chengdu, PR China Department of Oral and Maxillofacial Surgery Peking University School and Hospital of Stomatology Beijing People's Republic of China School of Geography and Environmental Science, Guizhou Normal University, Guiyang, Guizhou 550001, China Department of Chemical Engineering, Monash University, Clayton, Victoria 3800, Australia Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, People’s Republic of China Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China Department of Genetics The Education Ministry Key Laboratory of Resource Chemistry; Shanghai Key Laboratory of Rare Earth Functional Materials, and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors; Department of Chemistry; Shanghai Normal University; Shanghai 200234 Department of Thoracic Oncology II, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education) Peking University Cancer Hospital & Institute Beijing 100142 P. R. China L’Oréal Korean Innovation Center Seoul Korea; L’Oréal Research and Innovation Shanghai China The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University Wuxi China; The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University Wuxi China Computer Network Information Center, Chinese Academy of Sciences, Beijing, China Key Laboratory of Microbiology, College of Life Science; Heilongjiang University; Harbin P.R. China Department of Neurosurgery, First Affiliated Hospital of Nanchang University, Nanchang, People's Republic of China;; Department of Neurosurgery, Beijing ChaoYang Hospital, Capital Medical University, Beijing, People's Republic of China; State Key Laboratory of Marine Resource Utilization in South China Sea School of Materials Science and Engineering Hainan University Haikou 570228 P. R. China Key Laboratory of Nuclear Medicine, Ministry of Health, Jiangsu Key Laboratory of Molecular Nuclear Medicine Jiangsu Institute of Nuclear Medicine Wuxi Jiangsu China State Key Laboratory Cultivation Bases for Gas Geology and Gas Control, College of Safety Science and Engineering, Henan Polytechnic University, Jiaozuo 454003, China; The Collaboration Innovation Center of Coal Safety Production of Henan Province, Henan Polytechnic University, Jiaozuo 454003, China Department of Biomedical Engineering, College of Biotechnology, Guilin Medical University, Guilin, Guangxi 541004, P.R. China Department of Thoracic Surgery, The First People’sHospital of Yunnan Province, Yunnan Province, China Pain Management School of Medicine and Health Management Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Hepatobiliary Surgery, Peking University People’s Hospital; Beijing Key Surgical Basic Research Laboratory of Liver Cirrhosis and Liver Cancer Laboratory of Advanced Optoelectronic Materials Suzhou Key Laboratory of Novel Semiconductor‐optoelectronics Materials and Devices College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 China Interventional Ultrasound Department, Chinese PLA General Hospital, 28 Fuxing Rd., Beijing, 100853, China. Institute of Applied Mechanics; Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province; Zhejiang University; Hangzhou 310012; P. R. China Alkali Soil Natural Environmental Science Center, Northeast Forestry University/Key Laboratory of Saline-alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education, Harbin, P.R. China, School of Pharmacy, Anhui Medical University Hefei China; Institute for Liver Diseases of Anhui Medical University, Anhui Medical University Hefei China; The Key Laboratory of Major Autoimmune Disease, School of Pharmacy, Anhui Medical University Hefei China; The Key Laboratory of Anti‐inflammatory and Immune Medicines, Ministry of Education, Anhui Medical University Hefei China Department of Breast Surgery, Weifang People's Hospital, Weifang, Shandong 261041, P.R. China State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China School of Life Sciences, Tianjin University and Tianjin Engineering Center of Micro-Nano Biomaterials and Detection-Treatment Technology (Tianjin), Tianjin 300072, China School of Psychological and Cognitive Sciences and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, P.R. China Department of Cardiovascular Medicine the First Affiliated Hospital of Xi’an Jiaotong University Xi’an China Department of Cardiovascular Medicine, First Affiliated Hospital of Medical College, Xi’an Jiaotong University and Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education, Xi’an, People’s Republic of China; College of Automation, Harbin Engineering University, Harbin, Heilongjiang, China MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, USA. Department of Urology Qilu Hospital of Shandong University Jinan China Department of Mechanical Engineering, University of Texas at Dallas, Richardson, Texas 75080, United States Department of hand and foot surgery, The Second Hospital of Shandong University, China Hubei Institute for Food and Drug Control, Wuhan 430072, PR China Engineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural University, Changchun, China; College of Plant Protection, Shenyang Agricultural University, Shenyang, Ching Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education, China Pharmaceutical University, Nanjing, People’s Republic of China;; Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing, People’s Republic of China; Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, USA Department of Blood Vessels of Thyroid Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumchi, Xinjiang 830000, P.R. China Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education, School of Chemistry and Material Science, Heilongjiang University, Harbin 150080, P. R. China *Research School of Biology, Australian National University, Canberra, Australian Capital Territory; Department of Surgery, Naval Hospital of Eastern Theater, PLA Zhoushan 316000, Zhejiang, China. State of Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, CAMS and PUMC, Tianjin 300020, China. Beijing Key Laboratory of Nasal Diseases Beijing Institute of Otorinolaringology Beijing China Department of Pharmacology Lineberger Comprehensive Cancer Center University of North Carolina at Chapel Hill NC USA School of Computer Science, University of Technology Sydney, Ultimo, NSW, Australia Henan Provincial Engineering and Technology Research Center for Precise Synthesis of Fluorine-Containing Drugs, College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang, 455000, P. R. China Department of Hepatobiliary Surgery The Affiliated DrumTower Hospital of Nanjing University Medical School 210008 Nanjing China IMDEA Nanoscience 28049 Madrid Spain; Departamento de Química Módulo 13 Universidad Autónoma de Madrid 28049 Madrid Spain Department of Dermatology and Venereology, Peking University First Hospital, Beijing 100034, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing 100034, China; National Clinical Research Center for Skin and Immune Diseases, Beijing 100034, China Department of General Surgery Shenzhen Hospital of Armed Police Frontier Corps China Department of Surgery University of Minnesota Medical School 420 Delaware St. SE, MMC 195 Minneapolis Minnesota 55455 USA Department of Chemical Engineering; Monash University; Clayton; Australia Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China; National Clinical Research Center for Obstetrics and Gynecology, Beijing 100191, China; Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing 100191, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing 100191, China College of Chemistry and Molecular Engineering Peking University Beijing People's Republic of China Shanghai Jiao Tong University 2 Department of Physics and Astronomy, , Shanghai 200240, China Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang, P. R. China Department of Hepatobiliary Surgery, Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei 050051, P.R. China Department of Computer science, Tunghai University, Taichung, Taiwan Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai Institute for Pediatric Research, 1665 Kongjiang Road, Shanghai 200092, China Laboratory of Ethnopharmacology Institute of Integrated Traditional Chinese and Western Medicine Xiangya Hospital Central South University Changsha PR China Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China; Department of Allergy, Tongji Hospital, School of Medicine, Tongji University, Shanghai 200065, China ffiliated hospital of chengde medical college. Department of Statistics SJTU‐Yale Joint Centre for Biostatistics Shanghai Jiao Tong University Shanghai China Department of Radiation Oncology Huashan Hospital Fudan University Shanghai China Department of Stomatology, Yinchuan Stomatological Hospital, Yinchuan, Ningxia, China Department of Orthopaedics, Shanghai Ninth People's Hospital, Medical College of Shanghai Jiaotong University, Shanghai, 200011, PR China. Department of Medical Imaging, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of Oral Radiology, West China Hospital of Stomatology, Sichuan University, Chengdu, China Department of Neurology Ann Romney Center for Neurologic Diseases Brigham and Women's Hospital Harvard Medical School Boston MA USA Department of Pharmaceutics; College of Pharmacy; Shandong University; Jinan 250012; China Department of Emergency, Changhai Hospital, Naval Medical University Shanghai, China. Department of Orthopedics, Changhai Hospital, Naval Medical University Shanghai, China. Department of Immunology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. College of Basic Medical Sciences, Dalian Medical University, Dalian, P. R. China Department of Burn and Plastic Surgery, Yuhuangding Hospital, Shandong, China. 1 Department of Veterinary Pharmacology, College of Veterinary Medicine, China Agricultural University, Beijing, China Measurement Technology Group, Institute for Environmental Management Technology, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba 305-8569, Japan, Agricultural High-Tech Research Center, Meijo University, Nagoya 468-8502, Japan, and Department of Environmental Chemistry, Faculty of Engineering, Kyushu Kyoritsu University, Kitakyusyu 807-8585, Japan Lab of High Density Optical Storage; Shanghai Institute of Optics and Fine Mechanics; Chinese Academy of Sciences; Shanghai 201800; P. R. China Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, P. R. China; Department of Plastic and Reconstructive Surgery Peking Union Medical College Hospital Peking Union Medical College & Chinese Academy of Medical Sciences Beijing China Center of Interventional Oncology and Liver Diseases, Beijing You’an Hospital, Capital Medical University, Beijing, China; Zhuhui Yuan, Yang Wang, and Caixia Hu contributed equally to this work. Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China;; Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC; Department of Internal Medicine and Division of Nephrology and Hypertension University of Cincinnati Cincinnati OH; Dialysis Vascular Access Research Group Cincinnati OH Faculty of Materials Science and chemistry China University of Geosciences Wuhan 430074 P. R. China; Division of Chemistry and Biological Chemistry School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link Singapore 637371 Singapore The Institute of Chemical Physics; School of Chemistry; Beijing Institute of Technology; Beijing 100081; People's Republic of China Institute of Microsurgery on Extremities Shanghai Jiao Tong University Affiliated Sixth People' Hospital Shanghai China Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, China The Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi 214122, China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China Department of Obstetrics Sichuan Provincial Maternity and Child Health Care Hospital The Affiliated Women's and Children's Hospital of Chengdu Medical College Chengdu Sichuan Province China Shanghai Research Center for Modernization of Traditional Chinese Medicine; National Engineering Laboratory for TCM Standardization Technology; Shanghai Institute of Materia Medica; Shanghai Institutes for Biological Sciences; Chinese Academy of Sciences; Shanghai P. R. China Research Center for Analysis Sciences, Northeastern University, Shenyang 110004, China. Medical Research & Biometrics Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China Department of Chemistry and Center for Nanoscale Science, and Department of Chemical Engineering, Materials Research Institute, The Pennsylvania State University, University Park, Pennsylvania 16802 School of Chemistry and Chemical Engineering Yangzhou University Yangzhou 225002 P. R. China Department of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China;; University of Chinese Academy of Sciences, Beijing, 100049, China; State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, P. R. China Department of Entomology and Plant Pathology, Oklahoma State University, Stillwater, OK 74078, USA. Department of Biochemistry and Cell Biology, Institute for Cell and Developmental Biology, and Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-5215 Key Lab of Advanced Optoelectronic Quantum Architecture and Measurement (Ministry of Education) Beijing Key Lab of Nanophotonics & Ultrafine Optoelectronic Systems and School of Physics Beijing Institute of Technology Beijing 100081 China Institute of Microsurgery on Extremities Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China Department of Plant Nutrition, College of Resource and Environmental Sciences, Nanjing Agricultural University, No.1 Weigang Road, Nanjing 210095, Jiangsu Province, P.R. China and 2 Department of Pharmaceutical Sciences, College of Pharmacy, Oregon State University, Pharmacy Building Room 203, Corvallis, OR 97331–3507, USA Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, ), China Department of Biochemistry, Kansas State University, Manhattan, KS 66506 and the Department of Biostatistics & Informatics Center for Innovative Design & Analysis Colorado School of Public Health University of Colorado Aurora CO USA Department of Pediatrics, Qilu Hospital, Shandong University School of Medicine, Shandong, P.R. China. Shanxi Academy of Advanced Research and Innovation, Taiyuan 030032, China Department of Microbiology, Zhongshan School of Medicine, Key Laboratory for Tropical Diseases Control of the Ministry of Education, Sun Yat-sen University, Guangzhou 510080, China; The College of Chemistry and Molecular Engineering, Center of Computational Chemistry, Zhengzhou University, Zhengzhou, Henan Province, 450001, P.R. China Department of Dermatology and Venerology, Peking University First Hospital, Beijing, China; Department of Breast Surgery, Weifang People’s Hospital, Weifang, Shandong, China College of Veterinary Medicine, China Agricultural University , Beijing, China College of Biology Pharmacy and Food Engineering, Shangluo University, Shangluo, China; CapitalBio Genomics Co., Ltd. Dongguan China; CapitalBio Technology Co., Ltd. Beijing China Department of Neurosurgery, Anhui Provincial Hospital Affiliated to Anhui Medical University, 17 Lujiang Road, Hefei 230001, China. Department of Pathophysiology, Wenzhou Medical College, Wenzhou 325035, China. Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, P. R. China Hepatic Biliary and Pancreatic Cancer Center, Chongqing University Cancer Hospital, Chongqing, China School of Resources & the Environment; Northeast Agricultural University; Harbin; China Medical Research and Biometrics Center, National Center for Cardiovascular Diseases of China Beijing China Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China (mainland) Grandomics Biosciences, Beijing 100176, China State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences China Agricultural University Beijing 100193 China Liver Disease Center, Beijing YouAn Hospital Capital Medical University Beijing China National Reference Laboratory for Veterinary Drug Residue, Key Laboratory of Development and Evaluation of Chemical and Herbal Drugs for Animal Use, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing, China. Department of Orthopedics, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China Department of Computer Science, Faculty of Sciences, University of Manitoba, Winnipeg, Canada. Department of Radiotherapy Nanyang Central Hospital Nanyang Henan China State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China Department of Materials Science and Engineering and The Shenzhen Key Laboratory for Printed Organic Electronics, South University of Science and Technology of China, No. 1088, Xueyuan Road, Shenzhen 518055, Guangdong, P. R. China West Yunnan University of Applied Sciences, Jinghong, Yunnan, China; Metabo-Profile Biotechnology (Shanghai) Co. Ltd., Shanghai, China Department of Neurology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China Department of Cardiovascular Medicine, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, China Department of Orthopedics Department of Pharmacy The First Affiliated Hospital of Harbin Medical University The Second Affiliated Hospital of Harbin Medical University Harbin China; Department of Clinical Pharmacology College of Pharmacy Harbin Medical University Harbin China Department of Hepatology, The First Hospital of Jilin University, Changchun, Jilin Province, China Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi, China Department of Molecular Ecology, Max Planck Institute for Chemical Ecology, D-07745 Jena, Germany Institute of Rocket Force Medicine , State Key Laboratory of Trauma, Burns and Combined Injury, , 400038, Chongqing, China; Third Military Medical University (Army Medical University) , State Key Laboratory of Trauma, Burns and Combined Injury, , 400038, Chongqing, China Department of Urology Huangshi Central Hospital (Affiliated Hospital of Hubei Polytechnic University) Edong Healthcare Group Huangshi P.R. China; Hubei Province Key Laboratory of Occupational Hazard Identification and Control Wuhan University of Science and Technology Wuhan P.R. China MassBiologics of the University of Massachusetts Medical School, Boston, MA, USA The College of Chemistry and Molecular Engineering Zhengzhou University No. 100 Kexue Street Zhengzhou Henan 450001 P. R. China Beijing National Laboratory for Molecular Sciences, and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemisstry, Peking University, Beijing 100871, China Jiangsu Collaborative Innovation Center for Advanced Inorganic Function Composites, Nanjing Tech University, Nanjing 211816, China; College of Materials Science and Engineering, Nanjing Tech University, Nanjing 211816, China Aerosol and Air Quality Research Laboratory, Department of Energy, Environmental and Chemical Engineering, Washington University in St. Louis, St. Louis, Missouri. Department of Epidemiology, Fielding School of Public Health, University of California Los Angeles, CA (Y.W.) Jilin University Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS),School of Basic Medical Sciences,Shanghai Medical College,Fudan University,Shanghai,China Department of Gastroenterology Renmin Hospital of Wuhan University Wuhan Hubei Province China; Key Laboratory of Hubei Province for Digestive System Disease Renmin Hospital of Wuhan University Wuhan China; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision Renmin Hospital of Wuhan University Wuhan China School of Pharmacy, Fudan University, Shanghai 200032, China Department of Anesthesiology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, China National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, College of Bioengineering, Hubei University of Technology, Wuhan, China. Department of Biochemistry and Molecular Cell Biology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, and Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, Chengdu 610106, P. R. China Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Comprehensive Clinical Trial Ward, Peking University Cancer Hospital & Institute, Beijing, China; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Thoracic Oncology II, Peking University Cancer Hospital & Institute, Beijing, China 1Immunomedics, Inc., Morris Plains, New Jersey. National Emergency Medical Team, China Department of Pathology, Key Laboratory of Molecular Epigenetics of the Ministry of Education, Northeast Normal University, Changchun 130024, People’s Republic of China Pain and Translational Symptom Science University of Maryland School of Nursing Baltimore Maryland USA; Placebo Beyond Opinions (PBO) Center, School of Nursing University of Maryland Baltimore Maryland USA School of Energy and Environment, Anhui University of Technology, Ma’anshan 243002, China; School of Materials Science and Engineering, Anhui University of Technology, Ma’anshan 243032, China Key Laboratory of Mesoscopic Chemistry of Ministry of Education and Collaborative Innovation Center of Chemistry for Life Sciences School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 P. R. China School of Information Engineering, Shandong Management University, Jinan 250357, China Key Laboratory of Animal Molecular Nutrition of Education of Ministry; College of Animal Sciences; Zhejiang University; Hangzhou 310058 China; Key Laboratory of Animal Feed and Nutrition of Zhejiang Province; Hangzhou 310058 China Department of Medical Biochemistry and Biophysics Karolinska Institutet Stockholm SE‐17177 Sweden College of Chemistry, Sichuan University, Chengdu 610064, China; Key Laboratory for Soft Chemistry and Functional Materials, Nanjing University of Science and Technology, Ministry of Education, Nanjing 210094, China College of Plant Protection, Northwest A&F University, Yangling 712100, China From the *Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; and Departments of †Nuclear Medicine, ‡Urology, and §Radiology, Changhai Hospital, Second Military Medical University, Shanghai, China. Department of Systems Science, School of Management, Beijing Normal University 1 , Beijing 100875, People's Republic of China; Center for Complexity Research, Beijing Normal University 2 , Beijing 100875, People's Republic of China Capital Medical University Affiliated Beijing You’an Hospital Beijing China; Beijing Institute of Hepatology Beijing China Key Laboratory of Photochemical Conversion and Optoelectronic Materials; Technical Institute of Physics and Chemistry & University of Chinese Academy of Sciences; Chinese Academy of Sciences; Beijing 100190; P. R. China Research Center for Qinghai Healthy Development, Medical College, Qinghai University, Xining, Qinghai 810001, China; Department of Basic Medical Sciences, Medical College, Qinghai University, Xining, Qinghai 810016, China Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College MassBiologics University of Massachussetts Chan Medical School Boston Massachusetts USA Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China Department of Social Medicine School of Public Health China Medical University Shenyang China School of Chemistry and Materials Science, University of Science and Technology of China, Hefei 230026, Anhui, China Key Laboratory for Organic Electronics and Information Displays & Institute of Advanced Materials (IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials (SICAM), Nanjing University of Posts & Telecommunications, 9 Wenyuan Road, Nanjing 210023, China Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, Liaoning, P. R. China Key Laboratory for Green Chemical Technology of Ministry of Education; School of Chemical Engineering & Technology; Tianjin University; Tianjin 300072; China Department of Urology, Affiliated Wuxi No. 2 Hospital of Nanjing Medical University, Wuxi, China; Wuxi Medical School, Jiangnan University, Wuxi, China Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN Institute of Advanced Chemical Power Source, School of Chemical Engineering and Technology, Harbin Institute of Technology, Harbin 150001, China Department of Biotherapy, Cancer Center, West China Hospital, Sichuan University Chengdu China Department of Materials Science and Engineering Tokyo Institute of Technology 2‐12‐1 Ookayama, Meguro‐ku Tokyo 152‐8552 Japan State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology, Dalian 116024, China. *Department of Genetics, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030; Institute of Social Development National Development and Reform Commission Beijing China L'Oréal Research and Innovation Shanghai China From the Department of Occupational and Environmental Health, Peking University School of Public Health, Beijing, China (H.X., T.W., B.F., Q.Z., X.S., J.C., Y.Z., Y.W., W.H.); Key Laboratory of Molecular Cardiovascular Sciences of Ministry of Education, Health Science Center, Peking University, Beijing, China (H.X., T.W., S.L., B.F., Q.Z., X.S., T.Y., J.C., Y.Z., Y.W., L.Z., J.L., W.H.). State Key Laboratory of Supramolecular Structure and Materials, Jilin University, Changchun 130012, P. R. China Institute of Hematology; Changhai Hospital; Second Military Medical University; Shanghai 200433; China Jiangsu Institute of Hematology, Leukemia Research Unit, First Affiliated Hospital of Suzhou Medical College, 96 Shizi Street, Suzhou 215006, PR China Liver Disease Center Beijing YouAn Hospital Capital Medical University Beijing China; Beijing Municipal Key Laboratory of Liver Failure and Artificial Liver Treatment & Research Beijing YouAn Hospital Capital Medical University Beijing China Department of Hand Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, P. R. China Jilin Ginseng Academy, Changchun University of Chinese Medicine, Changchun, China; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China College of Pharmacy; Guangxi University of Chinese Medicine; Nanning 530200; China Key Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; School of Earth Science and Resources, Chang’an University, Xi’an 710054, China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Institute of Functional Materials, Donghua University, Research Base of Textile Materials for Flexible Electronics and Biomedical Applications (China Textile Engineering Society), Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, 2999 North Renmin Road, Shanghai201620, P. R. China Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, USA Department of Chemistry University of Illinois at Urbana–Champaign 600 South Mathews Avenue Urbana IL 61801 USA Division of Cancer Biology and Therapeutics, Departments of Surgery and Biomedical Sciences, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 P. R. China Department of Pediatrics, Southwest Hospital, Army Medical University, Chongqing, China; Department of Pediatrics, Southwest Hospital, Army Medical University, Chongqing, China School of Basic Medical Sciences, Southwest Medical University , Luzhou 646000 , China Department of Neurology, Xijing Hospital, Fourth Military Medical University, Xi’an, China; Department of Neurology, 980th Hospital of PLA Joint Logistical Support Force (Bethune International Peace Hospital), Shijiazhuang, China. Department of Earth, Ocean and Atmospheric Science, Florida State University, Tallahassee, Florida 32306, United States Division of CT and MRI, First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China; Graduate School of Heilongjiang University of Chinese Medicine, Harbin, China Department of Pathology Case Western Reserve University Cleveland Ohio USA The Education Ministry Key Laboratory of Resource Chemistry; Shanghai Key Laboratory of Rare Earth Functional Materials; and Shanghai Municipal Education Committee Key Laboratory of Molecular Imaging Probes and Sensors; Department of Chemistry; Shanghai Normal University From the Cardiology Department, Luigi Sacco Hospital, Milan, Italy (R.P., A.S., M.V.); Cardiac Electrophysiology Service, McGill University Health Center, Montreal, Canada (R.P., J.J., M.L.B., V.E.); Department of Cardiology, University of Pennsylvania, Philadelphia (P.S.); Cardiology Department, University of Foggia, Foggia, Italy (P.S., L.D.B.); Department of Biomedical Engineering, University of Texas, Austin (L.D.B., A.N.); Hôpital Sacre Cœur de Montréal, Montréal, Canada (V.E.); Texas Cardiac... *State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China;; †Department of Aquaculture, University of Chinese Academy of Sciences, Wuhan 430072, China; Key Laboratory of Pesticide and Chemical Biology Ministry of Education College of Chemistry Central China Normal University 430079 Wuhan P. R. China Changchun University of Science and Technology Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine Shanghai, China. Laboratory of Oral Microbiota and Systemic Diseases, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine Shanghai, China. National Clinical Research Center for Oral Diseases, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology Shanghai, China. From the *Department of Laboratory Medicine/Pathology, the ‡Department of Internal Medicine, and the §Howard Hughes Medical Institute and Center for Immunology, Washington University School of Medicine, St. Louis, Missouri 63110 The Science Center for Future Foods, Jiangnan University, Wuxi 214122, China; The Key Laboratory of Carbohydrate Chemistry and Biotechnology, Ministry of Education, Jiangnan University, Wuxi 214122, China McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712;, Key Laboratory of Synthetic and Self-Assembly Chemistry for Organic Functional Molecules, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China Department of Orthopaedics, First Affiliated Hospital of Xinjiang Medical University, Ürümqi, China Key Laboratory of Veterinary Etiological Biology, National/WOAH Foot and Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China College of Chemical Engineering Zhejiang University of Technology Hangzhou 310014 P. R. China School of Basic Medical Sciences, School of Pharmacy and State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Guizhou China; National Engineering Research Center of Miao’s Medicines and Engineering Research Center for the Development and Application of Ethnic Medicine and TCM Ministry of Education and Guizhou Provincial Key Laboratory of Pharmaceutics Guiyang Guizhou China Department of Breast Tianjin Medical University Cancer Institute and Hospital Tianjin China Department of Orthopedic Surgery, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China (mainland) Materials Science and Engineering Program, University of California, San Diego, La Jolla, California 92093, United States School of Management, Xi’an University of Science and Technology, China Department of Infectious Diseases The First Hospital of Jilin University Changchun China Department of Cardiology First Affiliated Hospital of Medical School Xi'an Jiaotong University Xi'an China; Key Laboratory of Molecular Cardiology of Shaanxi Province Xi'an China Guangzhou First People's Hospital; School of Medicine; South China University of Technology; Guangzhou 510006; P. R. China Department of Biotherapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.; National Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.; Tianjin's Clinical Research Center for Cancer, Tianjin, China.; Key Laboratory of Cancer Immunology and Biotherapy, Tianjin, China. College of Water Resources and Civil Engineering, China Agricultural University, Beijing, People’s Republic of China; Key Laboratory of Agricultural Engineering in Structure and Environment, Ministry of Agriculture and Rural Affairs, Beijing, People’s Republic of China; Beijing Engineering Research Center for Animal Healthy Environment, Beijing, People’s Republic of China Key Laboratory for Advanced Materials and Institute of Fine Chemicals; School of Chemistry & Molecular Engineering; East China University of Science & Technology; Shanghai 200237; P. R. China State Key Laboratory of Fine Chemicals School of Chemical Engineering Dalian University of Technology Dalian 116024 China Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China Department of Hematology, Institute of Hematology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China Department of Materials Science and Engineering Southern University of Science and Technology (SUSTech) No. 1088, Xueyuan Road Shenzhen Guangdong 518055 China State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, Jiangsu, China College of Materials Science & Engineering, Zhejiang University of Technology, Hangzhou 310014, China Evidence-based Medicine Research Center, Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi Department of Pharmaceutical Sciences, College of Pharmacy, 203 Pharmacy Building, Oregon State University, Corvallis, Oregon 97331-3507 From the Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio. Early Life Institute, State Key Laboratory of Continental Dynamics, Northwest University, Xi'an 710069, People's Republic of China Hefei National Laboratory for Physical Sciences at the Microscale CAS Key Laboratory of Soft Matter Chemistry Collaborative Innovation Center of Suzhou Nano Science and Technology Department of Chemistry University of Science and Technology of China Hefei Anhui 230026 P. R. China Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200233, China Contributions from the Department of Chemistry, Surface Science Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, Oldenburg Institut fur Reine und Angewandte Chemie, Carl von Ossietzky Universität, Carl-von-Ossietzky Str. 9-11, 26129 Oldenburg, Germany, and National Energy Technology Laboratory, Pittsburgh, Pennsylvania 15236 MassBiologics, University of Massachusetts Medical School, Boston, Massachusetts, USA Departments of Chemistry and Physics, The Pennsylvania State University, University Park, Pennsylvania 16802 Department of Chemistry, The Pennsylvania State University, University Park, Pennsylvania 16802 Key Laboratory of Food Nutrition and Safety, Ministry of Education, College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin 300457, China National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Chemistry and Chemical Engineering; Nantong University; Nantong; P.R. China Shanghai Jiao Tong University Shanghai China Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, No. 17, Block 3, Southern Renmin Road, Chengdu 610041, P. R. China Nextomics Biosciences, Wuhan, Hubei Pro, China Yun Kang School of Medicine and Health, NanFang College, Guangzhou, Guangdong 510970, P.R. China Department of Pharmaceutics, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey Key Laboratory of Biomechanics and Mechanobiology Ministry of Education Beijing Advanced Innovation Center for Biomedical Engineering School of Biological Science and Medical Engineering Beihang University No. 37 Xueyuan Road, Haidian District Beijing 100083 China Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin of Xinjiang Production and Construction Corps/College of Life Science, Tarim University, Alar 843300, PR China Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing) Department of Thoracic Oncology II Peking University Cancer Hospital and Institute Beijing China Department of Cardiovascular Surgery General Hospital of Northern Theater Command Shenyang China; Graduate School Liaoning University of Traditional Chinese Medicine Shenyang China; Department of Cardiothoracic Surgery The First Affiliated Hospital of Jinzhou Medical University Jinzhou China Department of Hepatobiliary Surgery, Peking University People’s Hospital, Beijing, China Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing, China; Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China; Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China; Beijing Laboratory of Allergic Diseases and Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, China Department of Pathology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, People’s Republic of China State Key Laboratory of Medical Molecular Biology, Haihe Laboratory of Cell Ecosystem, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100005, P. R. China State Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, the Innovation Academy of Seed Design, Institute of Hydrobiology, Chinese Academy of Sciences , Wuhan 430072 , China; University of Chinese Academy of Sciences , Beijing 100049 , China Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Chemical Engineering, Jiangsu Normal University, Xuzhou, 221116, China Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital Group Suqian Hospital and The Affiliated Suqian Hospital of Xuzhou Medical University, Suqian, Jiangsu 223800, P.R. China Chinese Academy of Sciences; University of Science and Technology of China Department of Orthodontics and Prosthodontics, North China University of Science and Technology Affiliated Hospital Tangshan 063000, Hebei Province, China. Center for Biomedical Engineering and Technology, University of Maryland, Baltimore, MD 21201; Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201 Specialty Corn Institute, College of Agronomy, Shenyang Agricultural University, Dongling Street, Shenhe District, Shenyang 110866, China; Institute of Crop Science, Chinese Academy of Agricultural Sciences, Zhongguancun South Street, Haidian District, Beijing 100081, China St Vincent's Hospital Melbourne Australia National Engineering Lab for TFT-LCD Materials and Technologies, and Department of Electronic Engineering, Shanghai Jiao Tong University, Shanghai 200240, People’s Republic of China National University of Defense Technology Department of Internal Medicine, University of Cincinnati, Cincinnati, OH Department of General Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, China Department of Pathology Chang Hai Hospital The 2nd Military Medical University Shanghai, China Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, MD, USA; Center to Advance Chronic Pain Research, University of Maryland, Baltimore, MD, US Neurology Department of Shenzhen Second People's Hospital/First Affiliated Hospital of Shenzhen University Health Science Center Shenzhen China State Key Laboratory of Geological Process and Mineral Resources, School of Earth Science and Resources China University of Geosciences Beijing 100083 China Architectural Engineering Institute, Huzhou Vocational & Technical College, Huzhou 313002, China; Huzhou Key Laboratory of Green Building Technology, Huzhou 313002, China Cardiovascular Department, First Affiliated Hospital of Medical College, Xi’an Jiaotong University Department of Hepatobiliary Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi 710032, P.R. China grid.43169.39 0000000105991243 Department of Pathogen Biology, School of Basic Medical Science Xi’an Medical University 710021 Xi’an Shaanxi China Nursing College, Jiangsu Vocational College of Medicine, Yancheng 224006, China. National R&D Center for Freshwater Fish Processing, and Engineering Research Center of Freshwater Fish High-value Utilization of Jiangxi Province, College of Life Science, Jiangxi Normal University, Nanchang, Jiangxi 330022, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China ‡Howard Hughes Medical Institute and Center for Immunology, Washington University School of Medicine, St. Louis, MO 63110 Department of Orthopedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China. Department of Chemistry, University of Illinois at Urbana—Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States From the *Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia; and Departments of †Nuclear Medicine, ‡Urology, and §Pathology, Changhai Hospital, Second Military Medical University, Shanghai, China. Key Laboratory for Organic Electronics & Information Displays (KLOEID); Nanjing University of Posts and Telecommunications; Nanjing 210046, P. R. China Medical Research & Biometrics Center, Fuwai Hospital, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 102300, China MassBiologics, Boston, Massachusetts, USA Beijing Advanced Innovation Center for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology, School of Engineering Medicine, Beihang University, Beijing 100083, China Department of MRI, The Third Hospital of Qinhuangdao, Qinhuangdao, Hebei, China School of Environmental Studies; China University of Geosciences; Wuhan 430074; People's Republic of China School of Life Sciences Anhui University Hefei Anhui China; Key Laboratory of Human Microenvironment and Precision Medicine of Anhui Higher Education Institutes Anhui University Hefei Anhui China State Key Laboratory of Molecular Engineering of Polymers & Department of Macromolecular Science; Fudan University; Shanghai 200433; China; Department of Biological and Chemical Engineering Department of Pediatrics, Pritzker School of Medicine, University of Chicago, Chicago, Illinois Department of Microbiology, New York University School of Medicine, New York, New York, USA; School of Medicine, Tsinghua University, Beijing, China State Key Laboratory of Fine Chemicals; School of Chemical Engineering; Dalian University of Technology; Dalian 116024; P. R. China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine; China Agricultural University; Beijing; China Department of Orthopedic Surgery Shanghai Sixth People's Hospital Shanghai Jiaotong University School of Medicine 600# Yishan Road Shanghai 200233 China Department of Physiology, Shihezi University School of Medicine, Shihezi 832002, Xinjiang Uygur Autonomous Region, China ; Key Laboratory of Xinjiang Endemic and Ethnic Disease, Shihezi University School of Medicine, Shihezi 832002, Xinjiang Uygur Autonomous Region, China ; Fundamental Medical School of Wuhan University, Wuhan 430071, Hubei Province, China. 63650 Military Hospital of PLA , Luoyang , People’s Republic of China Department of Hepatology, First Hospital of Jilin University, 71 Xin Min Street, Changchun, Jilin Province 130021, China Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China. From the Department of Orthopedic Surgery (W.Z.), National Emergency Medical Team (Y.W.), Department of Pulmonary and Critical Care Medicine (K.X.), Department of Nursing (H.Z.), Department of Infectious Diseases (Y.T.), and Department of Anesthesiology (J.X.), The Second Xiangya Hospital, Central South University, Changsha, China; Department of Anesthesiology and Perioperative Medicine, Universi Department of Spine Surgery, Ningbo No. 6 Hospital, Ningbo, China. Department of Orthopedics, Tengzhou Central People's Hospital, Tengzhou 277500, China. State Key Laboratory of Electronic Thin Films and Integrated Devices, School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China (UESTC), Chengdu 610054, P. R. China Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China; Key Laboratory of Interfacial Physics and Technology, Chinese Academy of Sciences, Shanghai 201800, China Institute of Advanced Technology, Heilongjiang Academy of Sciences, Harbin 150001, China Key Laboratory of Functional Protein Research of Guangdong Higher Education Institutes, Institute of Life and Health Engineering, College of Life Science and Technology, Jinan University, Guangzhou 510632, China State Key Laboratory of Cardiovascular Disease, Fuwai Hospital National Center for Cardiovascular Diseases, Peking Union Medical College & Chinese Academy of Medical Sciences Beijing China Laboratory of Ethnopharmacology, Institute of Integrated Traditional Medicine and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, China; National Key Clinical Specialist Vocational School of TCM Encephalopathy, Xiangya Hospital, Central South University, Changsha 410008, China; TCM Pharmacogenetics Laboratory, Central South University, Changsha 410008, China Departamento de Química, Módulo 13, Universidad Autónoma de Madrid, 28049 Madrid, Spain; Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA-Nanociencia), Cantoblanco, 28049 Madrid, Spain Department of Anesthesiology the First Affiliated Hospital of Harbin Medical University Harbin China Laboratory of Aging Research and Cancer Drug Target State Key Laboratory of Biotherapy National Clinical Research Center for Geriatrics West China Hospital Sichuan University Chengdu China Institute of Semiconductors, Chinese Academy of Sciences , Beijing 100083 , China Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation Medicine, Beijing 100850, China Key Laboratory of Engineering Dielectric and Applications, Ministry of Education, School of Electrical and Electronic Engineering, Harbin University of Science and Technology, Harbin 150080, China Department of Otorhinolaryngology–Head and Neck Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China Alkali Soil Natural Environmental Science Center, Northeast Forestry University, Harbin, Heilongjiang 150040, P.R. China Dialysis Vascular Access Research Group, Division of Nephrology, University of Cincinnati, Cincinnati, OH - USA School of public Health, Wannan Medical College, Wuhu,Anhui 241002, China.. 1983renxiaohua@163.com. MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage, School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin 150001, China Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China Department of Oral and Maxillofacial‐Head and Neck Oncology Ninth People's Hospital School of Medicine Shanghai Jiao Tong University Shanghai China Antibody Engineering Laboratory, State Key Laboratory of Natural Medicines, Department of Molecular Biology, School of Life Science & Technology, China Pharmaceutical University, Nanjing 210009, PR China State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Wuhan, China Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan 430023, China Department of Orthodontics School of Stomatology Jilin University Changchun 130021 People's Republic of China Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin.; Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin. At the time of the study, Frank A. Sloan was with and Yang Wang was a doctoral candidate in the Department of Economics, and Philip R. Costanzo was with the Department of Psychology, Duke University, Durham, NC. Patrick S. Malone is with the Department of Psychology, University of South Carolina, Columbia. Stefan G. Kertesz is with the Center for Surgical, Medical Acute Care Research and Transitions, Birmingham Veterans Administration Medical Center, and the University of Alabama at Birmingham School of... CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China State Key Laboratory of Chemistry and Utilization of Carbon Based Energy Resources, College of Chemistry, Xinjiang University, Urumqi 830017, China State Key Laboratory of Precision Spectroscopy, East China Normal University, Shanghai 200241, China Department of Orthopaedics, Changzheng Hospital Affiliated to the Second Military Medical University, Shanghai 200003, China Key Laboratory of Functional Inorganic Material Chemistry, Ministry of Education. School of Chemistry and Material Science, Heilongjiang University, Harbin 150080, P. R. China State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, Guizhou, People’s Republic of China; Guizhou Provincial Engineering Research Center for the Development and Application of Ethnic Medicine and TCM, Guizhou Medical University, Guizhou, People’s Republic of China; School of Pharmacy, Guizhou Medical University, Guizhou, People’s Republic of China Department of Cardiac Surgery, Affiliated Hospital of Hebei University, Baoding City, 071000, Hebei Province, China Tianjin Key Laboratory of Brain Science and Neural Engineering Academy of Medical Engineering and Translational Medicine Tianjin University Tianjin 300072 China Department of Anatomy, Norman Bethune Medical School, Jilin University, Department of Hand Surgery, First Affiliated Hospital of Jilin University, Changchun, Jilin Province, China. Intelligent Transport Systems Research Center Wuhan University of Technology Wuhan China; National Engineering Research Center for Water Transport Safety Wuhan University of Technology Wuhan China Fudan University Department of Materials Science 2005, Songhu Road, Shanghai CHINA Changchun University of Chinese Medicine, 130117, Changchun, China CAS Key Laboratory of Genome Sciences and Information, China Gastrointestinal Cancer Research Center, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University Department of Histology and Embryology, Institute of Neuroscience, Wenzhou Medical University, Wenzhou, P.R. China. National Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan 430072, China; Department of Neurotumor Disease Treatment Center Taihe Hospital Hubei University of Medicine Shiyan China Department of Acupuncture, Guang An Men Hospital, China Academy of Chinese Medical Sciences, Beijing, China Complex Systems Division, Beijing Computational Science Research Center , 100193, Beijing , China Department of Chemistry Boston College Chestnut Hill Massachusetts USA *Department of Pathology, University of Chicago, Chicago, IL 60637; Department of Chemistry University of Illinois at Chicago 845 W. Taylor Street Chicago IL 60607-7061 USA Department of Pharmacology, State Province Key Laboratories of Biomedicine-Pharmaceutics of China and Key Laboratories of Cardiovascular Research, Ministry of Education of China, Harbin Medical University, Harbin, Heilongjiang, People's Republic of China Hefei National Laboratory for Physical Sciences at the Microscale; Department of Chemistry; Hefei Science Center of CAS; University of Science and Technology of China; Hefei Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China; Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, China School of Pharmaceutical Sciences Key Laboratory of Biotechnology Pharmaceutical Engineering Wenzhou Medical University Wenzhou Zhejiang P. R. China School of Electric Engineering, Shanghai Dianji University, Shanghai 200240, P. R. China Department of Orthopedics Beijing Shijitan Hospital, Capital Medical University Beijing 100038 China Department of Internal Medicine Yixing People′s Hospital Jiangsu China The Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Road, Wuxi 214122, China Jilin Ginseng Academy, Changchun University of Chinese Medicine, Jilin, Changchun, China Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, People's Republic of China Department of Medical Microbiology and Immunology; Creighton University School of Medicine; Omaha NE USA State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Avenida da Universidade, Taipa, Macau 999078, P. R. China Department of Pharmacognosyl, School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China. School of Electronic and Communication Engineering, Shenzhen Polytechnic, 7098 Liuxian Street, Shenzhen 518000, China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing, People's Republic of China State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech University, Nanjing 211816, China Roger Adams Laboratory, Department of Chemistry, University of Illinois, Urbana, Illinois 61801, United States MassBiologics of University of Massachusetts Medical School, Boston Department of Neurosurgery, The First Affiliated Hospital of Medical College, Shihezi University, Shihezi, China Department of Ophthalmology, Shanghai Ninth People’s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China Tribology Research Institute, Key Laboratory of Advanced Technology of Materials, Ministry of Education, Southwest Jiaotong University, Chengdu 610031, China; Research Institute of Frontier Science, Southwest Jiaotong University, Chengdu 610031, China School of Mathematics, Southeast University, Nanjing, China a Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, People's Republic of China Beijing Engineering Research Center of Protein and Antibody, Sinocelltech Ltd. Beijing China Tulane University Department of Chemical and Biomolecular Engineering, , New Orleans, Louisiana 70118, USA Key Laboratory of Drug Targeting and Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu, People’s Republic of China; Department of Orthopedic Surgery, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai, China.; Institute of Microsurgery on Extremities, Shanghai Sixth People's Hospital, Shanghai, China. Department of Pharmacology Wuhan Children's Hospital Wuhan China Qingdao Municipal Center for Disease Control and Prevention, Qingdao Institute of Preventive Medicine Department of Interventional Neurosurgery, Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University. Beijing 100050, China. Department of Medical Oncology & Therapeutics Research, City of Hope National Medical Center, Duarte, CA, USA Department of Oral and Maxillofacial–Head and Neck Oncology, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Stomatology& Shanghai Research Institute of Stomatology, Shanghai, China; National Clinical Research Center of Stomatology, Shanghai, China College of Tourism and Cooking & College of Food Science and Engineering, Yangzhou University, Yangzhou 225127, China School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing, China;; Health-cultivation Laboratory of the Ministry Education, Beijing University of Chinese Medicine, Beijing, China;; Health-cultivation Laboratory of the Beijing, Beijing University of Chinese Medicine, Beijing, China College of Animal Science and Technology, Northwest A&F University , Yangling, Shaanxi 712100 , China Department of Gynaecology and Obstetrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China Department of Neurosurgery, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China Department of Chemistry, University of Illinois at Urbana−Champaign, Urbana, Illinois 61801, United States The Key Laboratory of Industrial Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi China; The Science Center for Future Foods Jiangnan University Wuxi China Science Center for Future Foods, Jiangnan University, Wuxi 214122, Jiangsu, China. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; University of Chinese Academy of Sciences, Beijing, China. Shanghai Research Center for Modernization of Traditional Chinese Medicine, National Engineering Laboratory for Traditional Chinese Medicine Standardization Technology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People’s Republic of China Center for X-Mechanics, Zhejiang University, Hangzhou 310012, P. R. China; Institute of Applied Mechanics, Zhejiang University, Hangzhou 310012, P. R. China; Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, Hangzhou 310012, P. R. China China Center for Health Development Studies, Peking University, Beijing, China Department of Chemistry University of Illinois at Chicago 845 W Taylor St., Room 4500 Chicago IL 60607 USA Department of Cardiovascular Medicine, First Affiliated Hospital of Xi’an Jiaotong University; Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi’an Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Otorhinolaryngology Head and Neck Surgery,Tongji Hospital,Tongji Medical University,Shanghai,200065,China. Department of Medicinal, College of Pharmacy, Liaoning University, Shenyang, China Department of Economics Lafayette College Easton PA USA McKetta Department of Chemical Engineering, University of Texas at Austin, Austin, Texas 78712, United States Institute of Rocket Force Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University (Army Medical University), Chongqing 400038, China Department of Neurosurgery, 2nd Ward, Taihe Hospital, Shiyan, Hubei, China (mainland) School of Engineering and Applied Science, Department of Energy, Environmental, and Chemical Engineering, Aerosol and Air Quality Research Laboratory, and Departments of Hand Surgery, Department of Hepatobiliary Surgery Xijing Hospital Fourth Military Medical University Xi’an China State Key Laboratory of Crop Stress Biology for Arid Areas, College of Agronomy, Northwest A&F University, Xianyang 712100, China School of Medical Laboratory, Tianjin Medical University, Tianjin 300203, China Radiation Oncology Centre Sydney Adventist Hospital Sydney NSW Australia; Centre for Medical Radiation Physics University of Wollongong Wollongong NSW Australia College of New Energy; State Key Laboratory of Heavy Oil Processing; China University of Petroleum (East China); Qingdao 266580; China Center for Reproductive Medicine, Henan Key Laboratory of Reproduction and Genetics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, 450052, China. Department of Plant Pathology Nanjing Agricultural University Nanjing Jiangsu 210095 China; The Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education Nanjing Jiangsu 210095 China Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, Nebraska, USA Department of Pathogen Biology School of Medicine Nankai University Tianjin China Department of Neurosurgery, First Affiliated Hospital of Medical College, Shihezi University, Shihezi, China State Key Laboratory of ASIC and System, Shanghai Institute of Intelligent Electronics & Systems, School of Microelectronics, Fudan University, Shanghai 200433, China Xinjiang Art Institute, Urumqi 830049, China. Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT College of Physical Science and Technology, Central China Normal University, Wuhan 430079, People's Republic of China Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin. Engineering Research Center of Nano‐Geomaterials of Ministry of Education Faculty of Materials Science and Chemistry China University of Geosciences Wuhan 430074 P. R. China; Division of Chemistry and Biological Chemistry School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link Singapore 637371 Singapore Institute for Advanced Materials (IAM) Academy of Advanced Optoelectronics South China Normal University Guangzhou 510006 China School of Biology and Biological Engineering, South China University of Technology, Guangzhou, Guangdong 510006, China Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA Department of Radiology, Xijing Hospital, Fourth Military Medical University, Xi'an, China. State Key Laboratory of Automotive Simulation and Control, Jilin University, Changchun 130025, China Medical Research and Biometrics Center State Key Laboratory of Cardiovascular Disease Fuwai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences and Peking Union Medical College Beijing China Department of Physics & Tsinghua-Foxconn Nanotechnology Research Centre, Tsinghua University, Beijing 100084, Peopleʼs Republic of China, and Department of Physics, Beijing Normal University, Beijing 100875, Peopleʼs Republic of China Qingdao Municipal Center for Disease Control and Prevention, Qingdao Institute of Preventive Medicine, Qingdao, China Department of Clinical Pharmacy Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital) Tongji Medical College Huazhong University of Science & Technology Wuhan China State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China; Department of Materials Science and Engineering and The Shenzhen Key Laboratory for Printed Organic Electronics, Southern University of Science and Technology of China (SUSTech), Shenzhen 518055, P. R. China From the National Laboratory of Biomacromolecules and Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China; and the Department of Pathology, University of Chicago, Chicago, IL. State Key Laboratory of Agricultural Microbiology, Division of Animal Infectious Disease, Huazhong Agricultural University, Wuhan, Hubei, China. Ocean University of China School of Medicine and Pharmacy 5 Yushan Road 266003 Qingdao CHINA Department of Cardiology, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, China; Key Laboratory of Molecular Cardiology of Shaanxi Province, Xi'an, China Department of Ultrasound, The General Hospital of PLA, 28 Fuxing Rd., Beijing 100853, China. College of Forestry Gansu Agricultural University Lanzhou Gansu China Department of Pharmacy, The Second Affiliated Hospital of Harbin Medical University Harbin 150081, China. Department of Clinical Pharmacology, College of Pharmacy, Harbin Medical University Harbin 150081, China. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Provincial Key Laboratory of Pharmaceutics, Guizhou Medical University, Guiyang 550004, Guizhou, PR China; School of Pharmacy, Guizhou Medical University, Guiyang 550004, Guizhou, PR China Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, China; Institute for Nutritional Sciences, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences, Shanghai, China Collaborative Innovation Center of Chemistry for Energy Materials, MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemical Engineering, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P.R. China. Department of Planned Immunization, Qingdao Municipal Center for Disease Control and Prevention, Qingdao Institute of Prevention Medicine, Qingdao, China Department of Orthopedics Department of Immunology, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science Beijing Normal University Beijing China; School of Natural Resources, Faculty of Geographical Science, Beijing Normal University Beijing China Institute of Cancer Stem Cell, Second Affiliated Hospital Collaborative Innovation Center of Oncology, Dalian Medical University, 116044 Dalian, China; Department of Urology, Xiangya Hospital, Central South University, Changsha, China. Department of Molecular Ecology Max Planck Institute for Chemical Ecology Hans‐Knöll‐Straße 8 D‐07745 Jena Germany From the Centre for Clinical Epidemiology and Biostatistics, Royal Newcastle Hospital (Y.W., L.L-Y.L., R.F.H., J.F.), and Department of Neurology, John Hunter Hospital (C.L.), New South Wales, Australia. Joseph Zilber School of Public Health, University of Wisconsin, Milwaukee, Milwaukee, Wisconsin Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agriculture University, Beijing, China Department of Pediatrics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong 510280, China. Department of Radiology, the Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, No. 321 Zhongshan Road, Nanjing 210008, China; School of Physical Science and Technology, Southwest Jiaotong University, Chengdu 611756, China School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China; Department of Materials Science and Engineering, Southern University of Science and Technology, Shenzhen 518055, China The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation; The key Laboratory of Chemical Biology of Fujian Province; State Key Laboratory of Physical Chemistry of Solid Surfaces; Collaborative Innovation Center of Chemistry for Energy Materials; Department of Chemical Biology School of Science, Minzu University of China, Beijing 100081, China; Optoelectronics Research Centre, Minzu University of China, Beijing 100081, China Center for Condensed Matter Science and Technology (CCMST), Department of Physics, Harbin Institute of Technology, Harbin 150001, China; Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, 637371 Singapore, Singapore The MOE Key Laboratory of Spectrochemical Analysis & Instrumentation, the Key Laboratory of Chemical Biology of Fujian Province, State Key Laboratory of Physical Chemistry of Solid Surfaces, Department of Chemistry, Department of Chemical Biology, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, China State Key Laboratory of Natural Medicines and Laboratory of Chemical Biology, China Pharmaceutical University, Nanjing, China School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; School of Environmental and Municipal Engineering, Qingdao Technological University, Qingdao, People’s Republic of China; Key Laboratory of Eco-Environmental Engineer and Pollution Remediation in Shandong Province, Qingdao, People’s Republic of China E-mail: docwy@sina.com. Seed Science Center, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou 310058, China Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Shanghai 201203, China Department of Orthopedics, Seventh Medical Center of PLA General Hospital, Beijing 100700, China State Key Laboratory of Earth Surface Processes and Resource Ecology, Faculty of Geographical Science Beijing Normal University Beijing China; School of Natural Resources, Faculty of Geographical Science Beijing Normal University Beijing China State Key Laboratory of Infrared Physics Shanghai Institute of Technical Physics Chinese Academy of Sciences Shanghai 200083 China Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi’an 710032, China Institute of Rocket Force Medicine, State Key Laboratory of Trauma, Burns and Combined Injury, Third Military Medical University (Army Medical University), Chongqing, China Department of Hepatobiliary and Pancreatic Surgery, Hubei Cancer Hospital, Wuhan, China; Laboratory of Science and Technology on Integrated Logistics Support, College of Intelligence Science and Technology, National University of Defense Technology , Changsha 410073, China Department of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI, 53226, USA. yangwang@mcw.edu. Department of Clinical Pharmacology Wuhan Children's Hospital Hubei China Department of Chemistry and Biochemistry; University of Maryland; USA Department of Radiology, Nanjing 210008, China; Key Laboratory of Molecular Epigenetics of the Ministry of Education, Northeast Normal University, Changchun 130024, P. R. China College of Life Science, Hebei United University, Tangshan 063000, Hebei Province, China. Department of Dermatology and Venereology, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China Neuroscience Institute, Department of Histology and Embryology, Wenzhou Medical College, Wenzhou, Zhejiang 325035, P.R. China. Department of Radiology Nanjing Drum Tower Hospital affiliated to Medical School of Nanjing University Nanjing China Department of Cell Biology, School of Life Sciences, Central South University, Changsha, Hunan, 410013, P. R. China. Laboratory of Advanced Optoelectronic Materials, College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China Department of Infectious Diseases, Center of Infectious Diseases and Pathogen Biology, The First Hospital of Jilin University, Changchun, People’s Republic of China Department of Cardiovascular Medicine The First Affiliated Hospital of Xi'an Jiaotong University Xi'an China Department of Pharmaceutics, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, and Department of Plant Biology and Pathology, The State University of New Jersey, New Brunswick, New Jersey 08854 Department of Pain and Translational Symptom Science School of Nursing University of Maryland Baltimore MD USA State Key Laboratory of Fine Chemicals Dalian University of Technology 2 Linggong Road, Hi-tech Zone 116024 Dalian China La Follette School of Public Affairs, University of Wisconsin – Madison, Madison, WI, USA Research Center for Tissue Engineering and Regenerative Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China 1Department of Biochemistry and Molecular Cell Biology, and State Grid Tianjin Electric Power Company, Tianjin, China. Immunomedics, Inc.; Morris Plains, NJ USA Department of Chemistry, Fudan University, Shanghai 200433, China College of Materials Science& Engineering Zhejiang University of Technology, Hangzhou 310014, P. R. China College of Food Science and Engineering, Tianjin University of Science and Technology, Tianjin, China Department of Materials Science & State Key Laboratory of ASIC and Systems Fudan University Shanghai 200438 P. R. China Department of Urology, Hanzhong Central Hospital, Hanzhong, Shaanxi 723000, P.R. China Key Laboratory of Otolaryngology Head and Neck Surgery (Ministry of Education of China) Beijing Institute of Otolaryngology Beijing China Beijing Institute of Genomics, Chinese Academy of Sciences, Chaoyang District, Beijing, China. Department of Critical Care Medicine, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai 200030, China Department of Ultrasound, Huaihe Hospital of Henan University, Kaifeng, Henan, China. Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China Department of Materials Science and Engineering Southern University of Science and Technology (SUSTech) No. 1088, Xueyuan Road Shenzhen 518055 Guangdong China; Key Laboratory of Functional Polymer Materials and State Key Laboratory of Medicinal Chemical Biology The Co‐Innovation Center of Chemistry and Chemical Engineering of Tianjin Institute of Polymer Chemistry College of Chemistry Nankai University Tianjin 300071 China Shaanxi Key Laboratory of Natural Products & Chemical Biology; College of Chemistry & Pharmacy; Northwest A&F University; Yangling 712100; P. R. China College of Plant Protection, Northwest A&F University, Yangling, Shaanxi 712100, People’s Republic of China Department of Epidemiology and Health Statistics, School of Public Health and Management, Chongqing Medical University, Chongqing, China Tribology Research Institute, State Key Laboratory of Traction Power, Southwest Jiaotong University, Chengdu 610031, China Department of Applied Chemistry, Graduate School of Engineering University of Toyama Gofuku 3190 Toyama 930-8555 Japan Alkali Soil Natural Environmental Science Center Northeast Forestry University/Key Laboratory of Saline‐alkali Vegetation Ecology Restoration in Oil Field, Ministry of Education Harbin 150040 China State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China. Guangdong Provincial Key Laboratory of industrial surfactant and Flexible Sensing Technology Research Center, Institute of Chemical Engineering Guangdong Academy of Sciences No 318, Chebeixi Road Guangzhou 510665 China; School of Chemical Engineering and Light Industry Guangdong University of Technology No. 100, Waihuanxi Road Guangzhou 510006 China Wuxi Fisheries College Nanjing Agricultural University Nanjing China Beijing Key Laboratory of Detection Technology for Animal‐Derived Food Safety, College of Veterinary Medicine China Agricultural University Beijing China Emergent Molecular Function Research Team RIKEN Center for Emergent Matter Science (CEMS) 2‐1 Hirosawa Wako Saitama 351‐0198 Japan College of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, China Key Laboratory of Green Printing CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences (ICCAS) Beijing Engineering Research Center of Nanomaterials for Green Printing Technology National Laboratory for Molecular Sciences (BNLMS) Beijing 100190 P. R. China Nanjing Medical University Nanjing Jiangsu China Department of Molecular Pharmacology and Therapeutics, Loyola University Chicago, Mawood, Illinois Institute of neuroscience; Department of histology and embryology; Wenzhou Medical University; Wenzhou Zhejiang P. R. China Nanjing Stomatological Hospital; Medical School of Nanjing University; Nanjing; P. R. China Chinese Academy of Sciences Department of Breast Surgery and Department of Emergency Medicine Center, Sichuan Provincial People's Hospital University of Electronic Science and Technology of China Chengdu 610064 P. R. China Institute of Cancer Stem Cell, Cancer Center, Dalian Medical University, Dalian, 116044, China. From the Institute of Molecular Cardiology, University of Louisville and the Jewish Hospital Heart and Lung Institute, Louisville, Ky. College of Biology Pharmacy and Food Engineering, Shangluo University, Shangluo, Shaanxi Province, China; Department of Physics, Pennsylvania State University, University Park, PA, USA. Department of Infectious Diseases, The First Hospital of Jilin University, Jilin, China Department of Medical Microbiology and Immunology Creighton University School of Medicine Omaha Nebraska Zhejiang Int'lmedicine Co., Ltd. Hangzhou China Department of Orthopedics-Spine Surgery Center, the Second Affiliated Hospital, Chongqing Medical University, Chongqing, China Department of Materials Science and State Key Laboratory of ASIC and system Fudan University Shanghai 200433 P. R. China Shanghai anti-doping laboratory; Shanghai University of Sport; Shanghai; China MassBiologics of the University of Massachusetts Chan Medical School, Boston, Massachusetts, USA Department of Medical Imaging Department of Orthopedics, Chongqing Medical University, Chongqing, China. 19163564@qq.com Lab of Computational Chemistry and Drug Design, Laboratory of Chemical Genomics; Peking University Shenzhen Graduate School; Shenzhen P.R. China Marsico Lung Institute/Cystic Fibrosis Center, The University of North Carolina at Chapel Hill, 6009 Thurston Bowles Bldg, Chapel Hill NC 27599-7248, USA Department of Pain and Translational Symptom Science, School of Nursing, University of Maryland, Baltimore, MD, United States Department of Chemistry and Center for Nanoscale Science, The Pennsylvania State University, University Park, Pennsylvania 16802 State Key Laboratory of Public Big Data, Guizhou University, Guiyang, Guizhou, China Hebei College of Industry and Technology, Shijiazhuang, Hebei 050091, China Department of General Surgery, Xinhua Hospital, Shanghai JiaoTong University, School of Medicine, Shanghai, China Department of Chemistry and State Key Laboratory on Synthetic Chemistry, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, China Director of Statistics Medical Research & Biometrics Center, National Center for Cardiovascular Disease, Fuwai Hospital, Beijing, China. Department of Agriculture and Biotechnology, Wenzhou Key Laboratory for Quality and Safty of Agriculture products, Wenzhou Vocational College of Science and Technology, 325006 Wenzhou, Zhejiang Province, China Department of Radiology. Department of Orthopaedic Surgery, the Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P.R. China MOE Key Laboratory of Functionalized Molecular Solids, Anhui Key Laboratory of Molecule-Based Materials (State Key Laboratory Cultivation Base), College of Chemistry and Materials Science, Anhui Normal University, Wuhu, Anhui 241002, China State Key Laboratory of Crop Stress Biology for Arid Areas/College of Agronomy, Northwest A&F University State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China; University of the Chinese Academy of Sciences, Beijing 100049, P. R. China The Second Affiliated Hospital, Anhui Medical University, China Department of Anesthesiology The Affiliated Yantai Yuhuangding Hospital of Qingdao University Yantai Shandong China Department of Urology, Shougang Hospital of Peking University, Beijing, China School of Physical Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai 201210, China National Clinical Research Center for Oral Diseases, Beijing, P.R. China; National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing, P.R. China; Beijing Key Laboratory of Digital Stomatology, Beijing, P.R. China; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, P.R. China National Engineering Research Centre of Urban Environmental Pollution Control, Beijing Key Laboratory for Risk Modeling and Remediation of Contaminated Sites, Beijing Municipal Research Institute of Eco-Environmental Protection, Beijing 100037, China College of Horticulture Science & Technology, Hebei Normal University of Science & Technology, Qinhuangdao, Hebei, China Department of Materials Science and Engineering, Southern University of Science and Technology (SUSTech), No. 1088, Xueyuan Road, Nanshan, Shenzhen, Guangdong 518055, China Center of Interventional Oncology & Liver Diseases, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China State Key Laboratory of High‐Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 P. R. China Research and Innovation Center L'Oréal China Shanghai China State Key Laboratory of Infrared Physics Shanghai Institute of Technical Physics Chinese Academy of Sciences 500 Yutian Road Shanghai 200083 China; State Key Laboratory of ASIC and System School of Microelectronics Fudan University Shanghai 200433 China Department of Psychology and Center for Cognition and Brain Studies The Chinese University of Hong Kong Hong Kong SAR China Department of Physics South China University of Technology Guangzhou 510641 China; South China Institute of Collaborative Innovation Dongguan 523808 P. R. China Department of Materials Science and State Key Laboratory of ASIC and System Fudan University Shanghai 200433 P. R. China School of Pharmacy, Fudan University, Shanghai 201203, China Department of Anesthesiology, Laboratory of Mitochondria and Metabolism, National Clinical Research Center for Geriatrics West China Hospital of Sichuan University Chengdu Sichuan China Medical Research and Biometrics Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College Chinese Academy of Medical Science Beijing China Department of Social Medicine, School of Public Health China Medical University Shenyang Liaoning China MU Center for Influenza and Emerging Infectious Diseases University of Missouri Columbia Missouri USA; Department of Molecular Microbiology and Immunology, School of Medicine University of Missouri Columbia Missouri USA; Bond Life Sciences Center University of Missouri Columbia Missouri USA Faculty of Materials Science and Chemistry China University of Geosciences Wuhan Hubei 430074 China Department of Clinical Pharmacy, Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China Institute for Materials Research; Tohoku University; Aoba-ku; Japan; Department of Mechanical Systems Engineering Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100191 P. R. China Department of Pathology,UT Southwestern Medical Center,Dallas,TX Shenzhen Huada Gene Research Institute, Shenzhen, China Institute of Microsurgery on Extremities, Shanghai Jiao Tong University Affiliated Sixth People's Hospital 3 , 600 Yishan Road, Shanghai 200233, People’s Republic of China; Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital 4 , 600 Yishan Road, Shanghai 200233, People’s Republic of China 1Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi’an Jiaotong University Health Science Center, Xi’an, China;; 2Key Laboratory of Environment and Genes Related to Diseases (Xi’an Jiaotong University), Ministry of Education of China, Xi'an, China; MOE Key Laboratory of Materials Physics and Chemistry in Extraordinary Conditions Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical Engineering Northwestern Polytechnical University Xi'an 710072 P. R. China Aix-Marseille Université, CINaM CNRS UMR 7325, 13288 Marseille, France, College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P.R. China, Molecular Simulation Engineering Laboratory, University of Trieste, 34127 Trieste, Italy, National Interuniversity Consortium for Material Science and Technology, Research Unit MOSE-DEA, Trieste University, Italy, Spectropole, Faculté de Saint-Jérôme, Marseille, France, and Aix-Marseille Université, LCB CNRS UMR 7283, 13402 Marseille, France Department of Economics, Lafayette College, Easton, PA 18042. School of Pharmaceutical Science, Liaoning University, Shenyang, 110000, China Authors' Affiliations: 1Pediatric Sleep Medicine, Department of Pediatrics, Comer Children's Hospital, The University of Chicago, Chicago, Illinois; and 2Department of Microbiology and Immunology, The University of Louisville, Louisville, Kentucky Department of Oncology The Second Affiliated Hospital of Nanjing Medical University Nanjing China Department of Emergency, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China State Key Laboratory of Organic−Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, 100029 Beijing, China Engineering Research Center for Animal Innovative Drugs and Safety Evaluation, Ministry of Education, College of Veterinary Medicine China Agricultural University Beijing 100094 China; National Key Laboratory of Veterinary Public Health and Safety, College of Veterinary Medicine China Agricultural University Beijing 100094 China MOE Key Laboratory of Bioinorganic and Synthetic Chemistry; School of Chemistry; Sun Yat-Sen University; Guangzhou; China Key Laboratory of Low-grade Energy Utilization Technologies and Systems, Chongqing University, Ministry of Education, Chongqing 400030, China; Institute of Engineering Thermophysics, School of Energy and Power Engineering, Chongqing University, Chongqing 400030, China 1Scientific Research Center for Translational Medicine, Department of Biotechnology, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China.; 3School of Life Science, Dalian University, Dalian, China. China University of Petroleum, Qingdao Economic and Technological Development Zone Changjiang Road 66 266580 Qingdao China IDEA Research Team, University of Illinois, Urbana, Illinois.; School of Social Work, University of Illinois at Urbana-Champaign, Urbana, Illinois. Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China; School of Engineering Medicine, Beihang University, Beijing 100083, China Laboratory of Physiological Hygiene and Department of Medicine, University of Minnesota, Minneapolis, Minnesota Shanghai Medical College of Fudan University, Shanghai, P.R. China; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, P.R. China; Department of Urology, Shanghai No.5 People's Hospital, Fudan University, Shanghai, P.R. China Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary MedicineChina Agricultural University 100193 Beijing China From the Department of Cardiovascular Surgery, Union Hospital (Z.W., K.Z., Y.L., P.Y., J.W., Y.W., F.L., J.L.) and Department of Biochemistry and Molecular Biology (Y.W.), Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; Department of Cardiology, Central Hospital of Wuhan, Wuhan, China (P.Y.); and Key Laboratory of Molecular Biophysics of the Ministry of Education, Cardio-X Institute, College of Life Science and Technology and Center for Human Genome Research (Y.Y... Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, China; Department of Psychology, University of Chinese Academy of Sciences, Beijing 10049, China 11National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College Fuwai Hospital, Beijing, China. e-mail: yang-wang@uiowa.edu Department of Computer Science and Technology, Tongji University , Shanghai 201804, China Department of Biomedical Engineering, College of Biotechnology of Guilin Medical University, Guilin, Guangxi 541004, P.R. China Department of Anesthesiology, People’s Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Clinical Research Center for Anesthesia Management , Urumqi 830001 , China Department of Materials Science and Engineering, Tokyo Institute of Technology, Tokyo 152-8552, Japan Department of Haematology St Vincent's Hospital Melbourne Victoria Australia Department of Orthopaedic, Ningbo No.6 Hospital Ningbo China School of Water Conservancy and Civil Engineering, Zhengzhou University, Zhengzhou 450001, China Department of Pharmaceutical Sciences, University of Colorado Skaags School of Pharmacy and Pharmaceutical Sciences, Aurora, CO 80045; ‡Department of Pathology and Committee on Immunology, University of Chicago, Chicago, IL 60637 Section of Sleep Medicine, Department of Pediatrics The University of Chicago Chicago Illinois USA State Key Laboratory of Coordination Chemistry, Collaborative Innovation Center of Chemistry for Life Sciences, Center for Multimolecular Organic Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China College of Chemistry; Jilin University; Changchun 130012; China School of Materials and Chemical Engineering; Hubei University of Technology; Wuhan 430068; China Institute of Urology, Jiangxi Medical College, Nanchang 330006, China. Department of Orthopedics The Second Hospital of Jilin University Changchun China Nuclear Chemistry Research Team, RIKEN Nishina Center for Accelerator-Based Science, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan State Key Laboratory of Polymer Physics and Chemistry; Changchun Institute of Applied Chemistry; Chinese Academy of Sciences; Changchun 130022; China Department of Gynecology and Obstetrics Shengjing Hospital of China Medical University Shenyang Liaoning China Department of Gastrointestinal Surgery, Affiliated Hospital of Guizhou Medical University, Guiyang, China Department of Pathophysiology School of Basic Medical Sciences Wenzhou Medical University Wenzhou China Chengdu Xingrong Renewable Energy Co. Ltd., Chengdu 610000, China Center of Stomatology, China-Japan Friendship Hospital, Beijing 100029, China Department of Biostatistics & Informatics, Center for Innovative Design & Analysis, Colorado School of Public Health, University of Colorado, Denver, CO Key Laboratory of Materials Physics, Institute of Solid State Physics, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Hefei 230031, P.R. China Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai China; Shanghai Jiao Tong University Affiliated Sixth People's Hospital, School of Biomedical EngineeringShanghai Jiao Tong University Shanghai China Department of Echocardiography, Fuwai Hospital, National Center for Cardiovascular Diseases, China School of Pharmacy Nanjing Medical University Nanjing China Department of Cardiovascular Medicine, First Affiliated Hospital of Medical College of Xi’an Jiaotong University, Xi’an 710061, P. R China; Key Laboratory of Environment and Genes Related to Diseases (Xi’an Jiaotong University), Ministry of Education, Xi’an 710061, P. R. China Department of Pathology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China. Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Peking University, Beijing 100871, China and State Key Laboratory of Oganometallic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China Department of Dermatology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin 130031, P.R. China Department of Gastrointestinal Surgery Northern Jiangsu People's Hospital Yangzhou China; Medical College of Yangzhou University Yangzhou China University of Illinois at Urbana-Champaign, School of Social Work, Urbana, Illinois.; Identifying Depression through Early Assessment (IDEA) Research Team, University of Illinois at Urbana-Champaign, Urbana, Illinois. Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106-4935 Department of Materials Science; State Key Laboratory of ASIC and Systems; Fudan University; Shanghai 200433; People's Republic of China Key Laboratory of Synthetic and Biological Colloids, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China Department of Orthopedics, Orthopedic Research Institute, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P. R. China. Department of Dermatology and Venereology Peking University First Hospital Beijing China; National Clinical Research Center for Skin and Immune Diseases Beijing China; Beijing Key Laboratory of Molecular Diagnosis on Dermatoses Beijing China School of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Key Laboratory of Advanced Ceramics and Processing Technology (Ministry of Education) Tianjin University Tianjin 300350 P. R. China Department of Molecular Genetics,University of Texas Southwestern Medical Center,Dallas,TX Peking University *Department of Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE 68178; Universidad Autónoma de Madrid Departamento de Química, C-9, , 28049 Madrid, Spain The First Affiliated Hospital of Anhui Medical University Hefei China Department of Radiology Medical College of Wisconsin Milwaukee Wisconsin MITT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage; Harbin Institute of Technology; Harbin 150001; China Department of Pathology, Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine, Shanghai, China. UCSD Department of Intensive Care Unit, People's Hospital of Tongling City, Tongling 244000, Anhui, China. Corresponding author: Lu Houqing, Email: anhuiluhouqing@163.com. The College of Chemistry and Molecular Engineering; Center of Computational Chemistry; Zhengzhou University; Zhengzhou; P. R. China Institute of Grain and Oil Quality and Safety, Academy of National Food and Strategic Reserves Administration, No.11 Baiwanzhuang Street, Xicheng District, Beijing 100037, China Department of Medical Oncology Monash Health Clayton Victoria Australia Department of Pathogenic Biology and Immunology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi’an, Shaanxi 710061, P.R. China Department of Histology and Embryology Institute of Neuroscience Wenzhou Medical University Wenzhou China Department of Plastic and Reconstructive Surgery, Nippon Medical School, Tokyo, Japan Hefei National Laboratory for Physical Sciences at the Microscale Fujian Institute of Innovation of Chinese Academy of Sciences School of Chemistry and Materials Science University of Science and Technology of China Hefei 230026 P.R. China Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry & University of Chinese Academy of Sciences, Chinese Academy of Sciences, Beijing 100190, P. R. China Department of Chemical Engineering University of Michigan 2300 Hayward Street Ann Arbor MI 48109 USA; Biointerfaces Institute University of Michigan 2800 Plymouth Road Ann Arbor MI 48109 USA; Translational Oncology Program University of Michigan Health System 1600 Huron Pkwy Ann Arbor MI 48109 USA 1Antibody Engineering Laboratory, School of Life Science & Technology, China Pharmaceutical University, Nanjing, China. Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, China Agricultural University, Beijing, People's Republic of China Institute of Oceanographic Instrumentation, Qilu University of Technology (Shandong Academy of Sciences), Qingdao, China; Shandong Provincial Key Laboratory of Marine Monitoring Instrument Equipment Technology, Qingdao, China; National Engineering and Technological Research Center of Marine Monitoring Equipment, Qingdao, China Department of Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing, China National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Provincial Cooperative Innovation Center of Industrial Fermentation, Hubei Key Laboratory of Industrial Microbiology, Hubei University of Technology, Wuhan, 430068, Hubei, China Beijing National Laboratory for Molecular Sciences, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry & Molecular Engineering, Peking University, Beijing 100871, P. R. China, Department of Molecular Biology, Beijing Institute of Transfusion Medicine, Beijing 100850, P. R. China, and Nitto Denko Technical Corporation, 501 Via Del Monte, Oceanside, California 92010 State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China; University of Chinese Academy of Sciences, Beijing, China School of Pharmacy, Fudan University Medical Research & Biometrics Center, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China. Zhejiang Traditional Chinese Medicine & Health Industry Group Co., Ltd., Hangzhou 310016, China Key Laboratory for Organic Electronics and Information Displays; Institute of Advanced Materials (IAM); Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM); Nanjing University of Posts & Telecommunications; Nanjing 210023 Department of General Surgery, Shandong University Qilu Hospital, Jinan, Shandong 250012, P.R. China Southwest University, China Materials Science and Engineering Program, University of California San Diego, La Jolla, California 92093, United States Department of Urology, Hainan Provincial People's Hospital, Haikou, People's Republic of China. State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing, 100049, China College of Materials Science and Engineering, Nanjing Tech University, Nanjing 211816, China College of Life Science, National R&D Center for Freshwater Fish Processing, Jiangxi Normal University, Nanchang, Jiangxi 330022, China Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University, Beijing 100871, China, College of Chemistry and Material Science, Sichuan Normal University, Chengdu, Sichuan 410066, China, and Department of Chemistry, China Agricultural University, Beijing 100094, China, and State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China First Affiliated Hospital of Nanchang University, Nanchang, China; Department of Urology, Hainan General Hospital, Haikou, Hainan 570105, P.R. China Department of Radiology Medical College of Wisconsin Milwaukee Wisconsin USA Beijing Key Laboratory of Clothing Materials R&D and Assessment; Beijing Engineering Research Center of Textile Nanofiber; School of Materials Science & Engineering; Beijing Institute of Fashion Technology; Beijing 100029 Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China. zhong555guo@163.com Department of Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland Nuclear Chemistry; Institute of Modern Physics; Chinese Academy of Sciences; Lanzhou; China Department of Plant Pathology, College of Plant Protection, Nanjing Agricultural University, Nanjing, China; Key Laboratory of Integrated Management of Crop Diseases and Pests, Ministry of Education, Nanjing, China State Key Laboratory of Crop Stress Biology in Arid Areas, Shaanxi Key Laboratory of Agricultural and Environmental Microbiology, College of Life Sciences Northwest A&F University Yangling Shaanxi People's Republic of China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China; Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Science Beijing 100049 China Department of Otolaryngology Head and Neck Surgery Beijing People's Republic of China School of Materials Science and Engineering Central South University Changsha 410083 P. R. China Institute of Solid State Physics, HFIPS Chinese Academy of Sciences Hefei 230031 P. R. China; University of Science and Technology of China Hefei 230026 P. R. China Department of Clinical Laboratory Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China. Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, P. R. China Department of Pharmacy (The University Key Laboratory of Drug Research, Heilongjiang Province), The Second Affiliated Hospital of Harbin Medical University , Harbin , People’s Republic of China; Department of Clinical Pharmacology, College of Pharmacy, Harbin Medical University , Harbin , People’s Republic of China School of Forensic Medicine, Shanxi Medical University, Taiyuan 030001, China. wysdfz@163.com Joseph J. Zilber School of Public Health, University of Wisconsin-Milwaukee Engineering Research Center of Edible and Medicinal Fungi, Chinese Ministry of Education Jilin Agricultural University Jilin Changchun China Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China; Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai, China Department of Histology and Embryology Institute of Neuroscience, Wenzhou Medical University Wenzhou P.R. China School of Chemistry and Chemical Engineering; Yangzhou University; Yangzhou 225002; China State Key Laboratory of Physical Chemistry of the Solid Surfaces, Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005, P. R. China Department of Acupuncture and Moxibustion, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China; School of Food and Biological Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, Jiangsu, China MassBiologics University of Massachusetts Medical School Boston Massachusetts USA Department of General Psychiatry, Shanghai Mental Health Center, Shanghai Jiaotong University, Shanghai, China College of Land and Resources, Hebei Agricultural University, Baoding, China Department of Radiology, Zhujiang Hospital, Southern Medical University, Haizhu District, Guangzhou, Guangdong, P.R. China Division of Immunology and Cell Biology, John Curtin School of Medical Research, The Australian National University, PO Box 334, Canberra, ACT 2601, Australia Department of Pediatrics, Comer Children’s Hospital, Pritzker School of Medicine, and Department of Ophthalmology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai Department of Radiology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China. Life Science and Technology College, Jinan University, Guangzhou 510632, China. Research Center of Emergency Management, Jinan University, Guangzhou 510632, China. Department of Statistics George Mason University 4400 University Drive MS 4A7 Fairfax VA U.S.A. Key Laboratory of Low-grade Energy Utilization Technologies and Systems (Chongqing University), Ministry of Education, Chongqing 400030, China; Institute of Engineering Thermophysics, School of Energy and Power Engineering, Chongqing University, Chongqing 400030, China Laboratory of Synthesis and Natural Products Institute of Chemical Sciences and Engineering Ecole Polytechnique Fédérale de Lausanne, EPFL-SB-ISIC-LSPN, BCH 5304 1015 Lausanne Switzerland Key Laboratory of Molecular Epigenetics of the Ministry of Education (MOE), Northeast Normal University, Changchun, China Key Laboratory of Plant Resource Conservation and Germplasm Innovation in Mountainous Region, Collaborative Innovation Center for Mountain Ecology & Agro-Bioengineering (CICMEAB), College of Life Sciences/Institute of Agro-bioengineering, Guizhou University, Guiyang, Guizhou, China State Key Laboratory of Petroleum Resources and Engineering, China University of Petroleum, Beijing, Beijing 102249, China Department of Oral and Maxillofacial‐Head and Neck Oncology Shanghai Ninth People's Hospital College of Stomatology Shanghai Jiao Tong University School of Medicine Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology National Clinical Research Center for Oral Diseases Shanghai China Key Laboratory for Organic Electronics and Information Displays (KLOEID) and Institute of Advanced Materials (IAM) Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM) Nanjing University of Posts and Telecommunications 9 Wenyuan Road Nanjing 210023 China Icon Cancer Centres Wahroonga NSW Australia Center for Reproductive Medicine, Peking University Third Hospital, Beijing, China. Key Laboratory of Green Printing Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China; CAS Research/Education Center for Excellence in Molecular Sciences Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China Department of Cardiovascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230022, P.R. China Department of Biotherapy, Cancer Research Institute The First Affiliated Hospital of China Medical University Shenyang Liaoning China Chemical Engineering and Resource Utilization, College of Chemistry, Northeast Forestry University, Harbin 150040, China College of Resources and Environmental Sciences, China Agricultural University and Key Laboratory of Arable Land Conservation (North China), Ministry of Agriculture, Beijing 100193, China Beijing Advanced Innovation Center for Food Nutrition and Human Health, College of Veterinary Medicine, China Agricultural University, Beijing, China. Department of Pathology, Second Xiangya Hospital, Central South University, Changsha 410011, China. Department of Medicine Veterans Affairs Connecticut Healthcare System Yale University New Haven CT USA; Department of Cardiology First Affiliated Hospital of Medical School Xi'an Jiaotong University Xi'an China School of Food Science and Technology Dalian Polytechnic University Dalian People's Republic of China; National Engineering Research Center of Seafood; Sub‐center for Shellfish, National Research & Development Center for Aquatic Product Processing Dalian People's Republic of China Medical Research and Biometrics Center, National Center for Cardiovascular Diseases, Beijing, China. School of Physical Science and Technology, ShanghaiTech University, 393 Middle Huaxia Road, Shanghai 201210, P. R. China University of Nebraska Medical Center, College of Public Health, Omaha, NE Laboratory of Immuno-Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou, Fujian Province, China; Fujian Key Laboratory of Translational Cancer Medicine, Fuzhou, Fujian province, China Department of Cardiology, Geriatric Cardiovascular Disease Research and Treatment Center, No. 252 Hospital of PLA, Baoding 071000, China Department of Neurosurgery, The First Affiliated Hospital of Nanchang University, Jiangxi, PR China (Z.Z., J.Z., X.J., Y.W., L.L.). Beijing Advanced Innovation Center for Biomedical Engineering, Medicine-Engineering Interdisciplinary Research Institute, Beihang University, Beijing 100083, China Department of Ultrasound, The First Affiliated Hospital of Hainan Medical University, Haikou, China The Key Laboratory of Synthetic and Biological Colloids Ministry of Education School of Chemical and Material Engineering Jiangnan University 1800 Lihu Road Wuxi 214122 China Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA China Agricultural University, College of Veterinary Medicine, Beijing, China. Faculty of Hepato‐Biliary‐Pancreatic Surgery Chinese People’s Liberation Army (PLA) General Hospital Beijing China Department of Orthopaedics China‐Japan Union Hospital of Jilin University Changchun China School of Basic Medical Sciences, Anhui Medical University, Hefei, Anhui 230032, China Key Laboratory of Polyoxometalate and Reticular Material Chemistry of the Ministry of Education, College of Chemistry, Northeast Normal University, Changchun, Jilin 130024, P. R. China Department of Cardiology, Kailuan Hospital, Tangshan 063000, China. Key Laboratory of Analytical Chemistry for Biology and Medicine (Ministry of Education); College of Chemistry and Molecular Sciences; Wuhan University; Wuhan; China Department of Spine Surgery, Third Affiliated Hospital of Sun Yat-Sen University, Sun Yat-Sen University , Guangzhou , GuangDong Province, 510000 , China Key Laboratory of Horticultural Plant Biology Ministry of Education Huazhong Agricultural University Wuhan Hubei 430070 China; Key Laboratory of Horticultural Crop Biology and Genetic improvement (Central Region) Ministry of Agriculture Huazhong Agricultural University Wuhan Hubei 430070 China; The Institute of Citrus Science Huazhong Agricultural University Wuhan Hubei 430070 China |
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