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Schiemann K, Finsinger D, Zenke F, Amendt C, Knöchel T, Bruge D, Buchstaller H, Emde U, Stähle W, Anzali S. The discovery and optimization of hexahydro-2H-pyrano[3,2-c]quinolines (HHPQs) as potent and selective inhibitors of the mitotic kinesin-5. Bioorganic & Medicinal Chemistry Letters. 2010 Mar;20(5):1491–5. doi: 10.1016/j.bmcl.2010.01.110. |