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bibliographicCitation Khonde LP, Müller R, Boyle GA, Reddy V, Nchinda AT, Eyermann CJ, Fienberg S, Singh V, Myrick A, Abay E, Njoroge M, Lawrence N, Su Q, Myers TG, Boshoff HIM, Barry CE, Sirgel FA, van Helden PD, Massoudi LM, Robertson GT, Lenaerts AJ, Basarab GS, Ghorpade SR, Chibale K. 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis. J. Med. Chem. 2021 Aug 20;64(17):12790–807. doi: 10.1021/acs.jmedchem.1c00837.
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date 2021-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
identifier https://doi.org/10.1021/acs.jmedchem.1c00837
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language English
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title 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in Mycobacterium tuberculosis
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808233_AID1784352_PMID34414766_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469818366_AID1784352_PMID34414766_VALUE45
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784378_PMID34414766_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784360_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784346_PMID34414766_VALUE34
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469826139_AID1784346_PMID34414766_VALUE56
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784378_PMID34414766_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784372_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805666_AID1784352_PMID34414766_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784354_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784377_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784352_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784372_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805154_AID1784352_PMID34414766_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784346_PMID34414766_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784380_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815068_AID1784352_PMID34414766_VALUE37
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784373_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784362_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784348_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784373_PMID34414766_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168230_AID1784363_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469817580_AID1784352_PMID34414766_VALUE43
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469800708_AID1784352_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784362_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784379_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784377_PMID34414766_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784375_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469810038_AID1784346_PMID34414766_VALUE25
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805432_AID1784346_PMID34414766_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812808_AID1784352_PMID34414766_VALUE29
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820120_AID1784376_PMID34414766_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784372_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168230_AID1784361_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784361_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784373_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828463_AID1784376_PMID34414766_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814061_AID1784352_PMID34414766_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813148_AID1784346_PMID34414766_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469817942_AID1784346_PMID34414766_VALUE44
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784372_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784361_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784378_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784350_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469816123_AID1784352_PMID34414766_VALUE41
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820120_AID1784375_PMID34414766_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784376_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820120_AID1784372_PMID34414766_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784359_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784381_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805786_AID1784381_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821971_AID1784346_PMID34414766_VALUE51
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784378_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805786_AID1784376_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828463_AID1784373_PMID34414766_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784353_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803675_AID1784375_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784375_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784376_PMID34414766_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784374_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807791_AID1784346_PMID34414766_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469823918_AID1784346_PMID34414766_VALUE54
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828463_AID1784352_PMID34414766_VALUE58
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784373_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784377_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784347_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784381_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469822098_AID1784346_PMID34414766_VALUE52
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469802681_AID1784352_PMID34414766_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784379_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784362_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820120_AID1784378_PMID34414766_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821738_AID1784346_PMID34414766_VALUE50
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784379_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805406_AID1784346_PMID34414766_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815608_AID1784352_PMID34414766_VALUE38
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784358_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469816123_AID1784346_PMID34414766_VALUE41
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807791_AID1784352_PMID34414766_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808233_AID1784346_PMID34414766_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168230_AID1784362_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784352_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828400_AID1784352_PMID34414766_VALUE57
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469810658_AID1784346_PMID34414766_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784346_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804655_AID1784352_PMID34414766_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469823918_AID1784352_PMID34414766_VALUE54
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820120_AID1784380_PMID34414766_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815043_AID1784346_PMID34414766_VALUE36
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784372_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801725_AID1784346_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784349_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469810658_AID1784352_PMID34414766_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784367_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784372_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805154_AID1784346_PMID34414766_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103512882_AID1784353_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784354_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136926966_AID1784360_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784361_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815068_AID1784346_PMID34414766_VALUE37
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801725_AID1784352_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784384_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821738_AID1784352_PMID34414766_VALUE50
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784352_PMID34414766_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784356_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784380_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784355_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821507_AID1784346_PMID34414766_VALUE49
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820023_AID1784352_PMID34414766_VALUE46
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805786_AID1784352_PMID34414766_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784358_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803675_AID1784381_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807609_AID1784346_PMID34414766_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784377_PMID34414766_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803675_AID1784378_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784380_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784364_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784380_PMID34414766_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784373_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784375_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784379_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469817942_AID1784352_PMID34414766_VALUE44
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784362_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784363_PMID34414766_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784377_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784380_PMID34414766_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814061_AID1784346_PMID34414766_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784374_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469826139_AID1784352_PMID34414766_VALUE56
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136926966_AID1784361_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798856_AID1784346_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803675_AID1784352_PMID34414766_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805666_AID1784346_PMID34414766_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821507_AID1784352_PMID34414766_VALUE49
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828463_AID1784377_PMID34414766_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168230_AID1784353_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784351_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469809274_AID1784352_PMID34414766_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803675_AID1784346_PMID34414766_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813148_AID1784352_PMID34414766_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784353_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784373_PMID34414766_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784352_PMID34414766_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784386_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784378_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136926966_AID1784356_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469817131_AID1784346_PMID34414766_VALUE42
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784368_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784375_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799303_AID1784358_PMID34414766_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805786_AID1784375_PMID34414766_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784369_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815608_AID1784346_PMID34414766_VALUE38
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784356_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798419_AID1784346_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784375_PMID34414766_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469822098_AID1784352_PMID34414766_VALUE52
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814930_AID1784378_PMID34414766_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808890_AID1784352_PMID34414766_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784359_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799123_AID1784376_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469825535_AID1784352_PMID34414766_VALUE55
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804568_AID1784381_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136926966_AID1784355_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828463_AID1784379_PMID34414766_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID136926966_AID1784362_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814443_AID1784359_PMID34414766_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808963_AID1784355_PMID34414766_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784346_PMID34414766_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784388_PMID34414766_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814669_AID1784352_PMID34414766_VALUE34
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813467_AID1784376_PMID34414766_VALUE7

Total number of triples: 392.