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bibliographicCitation Chen Y, Wu J, Wang A, Qi Z, Jiang T, Chen C, Zou F, Hu C, Wang W, Wu H, Hu Z, Wang W, Wang B, Wang L, Ren T, Zhang S, Liu Q, Liu J. Discovery of N -(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC. European Journal of Medicinal Chemistry. 2017 Oct;139():674–97. doi: 10.1016/j.ejmech.2017.08.035.
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date 2017-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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title Discovery of N -(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404656937_AID1350802_PMID28850922_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103728028_AID1350826_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404651889_AID1350801_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661504_AID1350801_PMID28850922_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350883_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103728028_AID1350813_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350818_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350802_PMID28850922_VALUE28
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103583785_AID1350814_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104245790_AID1350820_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350851_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103728028_AID1350818_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662275_AID1350801_PMID28850922_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350893_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350825_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350894_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652340_AID1350801_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350855_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657914_AID1350802_PMID28850922_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350832_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104245790_AID1350834_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666688_AID1350801_PMID28850922_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661148_AID1350802_PMID28850922_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350853_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404655152_AID1350801_PMID28850922_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350839_PMID28850922_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350838_PMID28850922_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664976_AID1350802_PMID28850922_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662264_AID1350802_PMID28850922_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103583785_AID1350801_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404655083_AID1350801_PMID28850922_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350868_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661148_AID1350801_PMID28850922_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350890_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350819_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404672305_AID1350802_PMID28850922_VALUE33
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350866_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662525_AID1350801_PMID28850922_VALUE25
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350804_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661504_AID1350802_PMID28850922_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104245790_AID1350814_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350809_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104245790_AID1350817_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350832_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350870_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350839_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350842_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350887_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657003_AID1350801_PMID28850922_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662525_AID1350802_PMID28850922_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350820_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666862_AID1350801_PMID28850922_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350831_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350847_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350850_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350824_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350865_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104245790_AID1350821_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103728028_AID1350825_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350846_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350880_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350817_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350888_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350835_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350856_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350833_PMID28850922_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666688_AID1350802_PMID28850922_VALUE29
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350873_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104245790_AID1350816_PMID28850922_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664966_AID1350802_PMID28850922_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664966_AID1350801_PMID28850922_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103728028_AID1350827_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350854_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666318_AID1350814_PMID28850922_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350841_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350852_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350889_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404665508_AID1350848_PMID28850922_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404655378_AID1350801_PMID28850922_VALUE8
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID238
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1956

Total number of triples: 311.