Yoon S, Choi S, Eboreime J, Gelb B, Calabrese P, Arnheim N. Age-Dependent Germline Mosaicism of the Most Common Noonan Syndrome Mutation Shows the Signature of Germline Selection. The American Journal of Human Genetics. 2013 Jun;92(6):917–26. doi: 10.1016/j.ajhg.2013.05.001.