Chukwumezie BN, Wojcik M, Malak P, D'Amico F, Adeyeye MC. Factorial Design in the Spheronization of Ibuprofen Microparticulates Using the Rotor Disk Fluid‐Bed Technology. Pharmaceutical Development and Technology. 2004 Jan;9(1):49–62. doi: 10.1081/pdt-120027418.