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Cumming JG, Bower JF, Waterson D, Faull A, Poyser PJ, Turner P, McDermott B, Campbell AD, Hudson J, James M, Winter J, Wood C. The design and synthesis of novel, potent and orally bioavailable N-aryl piperazine-1-carboxamide CCR2 antagonists with very high hERG selectivity. Bioorganic & Medicinal Chemistry Letters. 2012 Jun;22(12):3895–9. doi: 10.1016/j.bmcl.2012.04.118. |