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Lee SL, Alexander RS, Smallwood A, Trievel R, Mersinger L, Weber PC, Kettner C. New inhibitors of thrombin and other trypsin-like proteases: hydrogen bonding of an aromatic cyano group with a backbone amide of the P1 binding site replaces binding of a basic side chain. Biochemistry. 1997 Oct 28;36(43):13180–6. doi: 10.1021/bi970912m. PMID: 9341205. |