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bibliographicCitation Khadka DB, Park S, Jin Y, Han J, Kwon Y, Cho W. Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors. European Journal of Medicinal Chemistry. 2018 Jan;143():200–15. doi: 10.1016/j.ejmech.2017.11.011.
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date 2018-01-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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language English
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title Design, synthesis, and biological evaluation of 1,3-diarylisoquinolines as novel topoisomerase I catalytic inhibitors
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401813_PMID29174815_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104234176_AID1401827_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404715583_AID1401815_PMID29174815_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401825_PMID29174815_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401808_PMID29174815_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401810_PMID29174815_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698760_AID1401810_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404710723_AID1401810_PMID29174815_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404708856_AID1401814_PMID29174815_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404703583_AID1401826_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401815_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711670_AID1401815_PMID29174815_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104234257_AID1401809_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401826_PMID29174815_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698911_AID1401826_PMID29174815_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714352_AID1401813_PMID29174815_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696393_AID1401810_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404717180_AID1401812_PMID29174815_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716979_AID1401828_PMID29174815_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404710723_AID1401814_PMID29174815_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404717180_AID1401827_PMID29174815_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401808_PMID29174815_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401808_PMID29174815_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714634_AID1401828_PMID29174815_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404717180_AID1401825_PMID29174815_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401817_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401814_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716929_AID1401826_PMID29174815_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716979_AID1401809_PMID29174815_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401827_PMID29174815_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104234176_AID1401828_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401825_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401808_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401818_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401810_PMID29174815_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401812_PMID29174815_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974065_AID1401829_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401815_PMID29174815_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168388_AID1401825_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404715583_AID1401828_PMID29174815_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404717180_AID1401811_PMID29174815_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713453_AID1401813_PMID29174815_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713453_AID1401808_PMID29174815_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401811_PMID29174815_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401809_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401814_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698911_AID1401825_PMID29174815_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401827_PMID29174815_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714352_AID1401809_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401810_PMID29174815_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401808_PMID29174815_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404715583_AID1401812_PMID29174815_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714634_AID1401809_PMID29174815_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401828_PMID29174815_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716979_AID1401814_PMID29174815_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698760_AID1401811_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404708856_AID1401828_PMID29174815_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716929_AID1401813_PMID29174815_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716979_AID1401827_PMID29174815_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696616_AID1401828_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401826_PMID29174815_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404710723_AID1401826_PMID29174815_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404699605_AID1401814_PMID29174815_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698760_AID1401809_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401813_PMID29174815_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716929_AID1401825_PMID29174815_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716979_AID1401825_PMID29174815_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401827_PMID29174815_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698760_AID1401828_PMID29174815_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104234176_AID1401826_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104234257_AID1401811_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401829_PMID29174815_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401825_PMID29174815_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698911_AID1401809_PMID29174815_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711151_AID1401812_PMID29174815_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401809_PMID29174815_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401810_PMID29174815_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401831_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714352_AID1401810_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698760_AID1401812_PMID29174815_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716979_AID1401826_PMID29174815_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404717180_AID1401808_PMID29174815_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714352_AID1401808_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404699605_AID1401815_PMID29174815_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404703583_AID1401827_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696616_AID1401813_PMID29174815_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401828_PMID29174815_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713453_AID1401826_PMID29174815_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698911_AID1401812_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696616_AID1401815_PMID29174815_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404699605_AID1401828_PMID29174815_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404704930_AID1401821_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696616_AID1401825_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714634_AID1401825_PMID29174815_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401814_PMID29174815_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696616_AID1401808_PMID29174815_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713453_AID1401812_PMID29174815_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713453_AID1401825_PMID29174815_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404715583_AID1401826_PMID29174815_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714634_AID1401815_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404703583_AID1401829_PMID29174815_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401826_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404710723_AID1401815_PMID29174815_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401811_PMID29174815_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401813_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698911_AID1401808_PMID29174815_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696393_AID1401813_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713453_AID1401828_PMID29174815_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404717180_AID1401815_PMID29174815_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404714352_AID1401826_PMID29174815_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404698760_AID1401815_PMID29174815_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716929_AID1401810_PMID29174815_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696393_AID1401808_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401815_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404706750_AID1401811_PMID29174815_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401814_PMID29174815_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404703583_AID1401813_PMID29174815_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168388_AID1401828_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401813_PMID29174815_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401829_PMID29174815_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404703583_AID1401828_PMID29174815_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404700679_AID1401815_PMID29174815_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103168388_AID1401827_PMID29174815_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696616_AID1401827_PMID29174815_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404703583_AID1401809_PMID29174815_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404713672_AID1401827_PMID29174815_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404711670_AID1401808_PMID29174815_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404708856_AID1401825_PMID29174815_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404696540_AID1401809_PMID29174815_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404716929_AID1401828_PMID29174815_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404708856_AID1401809_PMID29174815_VALUE12
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7153
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7150

Total number of triples: 355.