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bibliographicCitation Mahboobi S, Sellmer A, Winkler M, Eichhorn E, Pongratz H, Ciossek T, Baer T, Maier T, Beckers T. Novel chimeric histone deacetylase inhibitors: a series of lapatinib hybrides as potent inhibitors of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and histone deacetylase activity. J Med Chem. 2010 Dec 23;53(24):8546–55. doi: 10.1021/jm100665z. PMID: 21080629.
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identifier https://doi.org/10.1021/jm100665z
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language English
source https://pubmed.ncbi.nlm.nih.gov/
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title Novel Chimeric Histone Deacetylase Inhibitors: A Series of Lapatinib Hybrides as Potent Inhibitors of Epidermal Growth Factor Receptor (EGFR), Human Epidermal Growth Factor Receptor 2 (HER2), and Histone Deacetylase Activity
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546554_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546557_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546559_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546545_PMID21080629_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546553_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546562_PMID21080629_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546564_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546560_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546562_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546550_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546559_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546545_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546549_PMID21080629_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546557_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546545_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546563_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546545_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546561_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546551_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546548_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546558_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546558_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546564_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546547_PMID21080629_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103174146_AID546560_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546558_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546566_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546545_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103611582_AID546546_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546550_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546550_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546550_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546556_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546562_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546546_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546547_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546553_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546551_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546550_PMID21080629_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546555_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546558_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546552_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546552_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956213_AID546545_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546556_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546549_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103174146_AID546559_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546553_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546556_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546561_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546548_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546547_PMID21080629_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546548_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546549_PMID21080629_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546562_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546549_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546563_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546549_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546548_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546560_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546552_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546545_PMID21080629_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546552_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546555_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956213_AID546556_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546548_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546555_PMID21080629_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546565_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546552_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546551_PMID21080629_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546564_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546552_PMID21080629_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546563_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103174146_AID546548_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546554_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546559_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546554_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546554_PMID21080629_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956213_AID546560_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546558_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124976269_AID546557_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546553_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546554_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546553_PMID21080629_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546563_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546554_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546549_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546555_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546545_PMID21080629_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546558_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103611582_AID546545_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546548_PMID21080629_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546557_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546553_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546562_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546549_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546563_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546561_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546555_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546558_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956213_AID546551_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103611582_AID546548_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956213_AID546550_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546553_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546546_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546559_PMID21080629_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103611582_AID546550_PMID21080629_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546550_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124969426_AID546551_PMID21080629_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546558_PMID21080629_VALUE1
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546553_PMID21080629_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546560_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124957901_AID546548_PMID21080629_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546567_PMID21080629_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546556_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103177479_AID546546_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956215_AID546555_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956213_AID546557_PMID21080629_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966726_AID546550_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961475_AID546564_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124956214_AID546559_PMID21080629_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546560_PMID21080629_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124958834_AID546545_PMID21080629_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546546_PMID21080629_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546547_PMID21080629_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124974653_AID546561_PMID21080629_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961476_AID546548_PMID21080629_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124961477_AID546546_PMID21080629_VALUE11
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5347
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID51564
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1017
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID83933
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3643
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID10014
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID10013
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2064
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID127494626
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5159
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3065
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1956
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3066
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8841
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID9734
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID9759
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID55869
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID79885

Total number of triples: 381.