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publicationName European Journal of Medicinal Chemistry
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bibliographicCitation Xia Z, Huang R, Zhou X, Chai Y, Chen H, Ma L, Yu Q, Li Y, Li W, He Y. The synthesis and bioactivity of pyrrolo[2,3-d]pyrimidine derivatives as tyrosine kinase inhibitors for NSCLC cells with EGFR mutations. European Journal of Medicinal Chemistry. 2021 Nov;224():113711. doi: 10.1016/j.ejmech.2021.113711.
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date 2021-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
identifier https://pubmed.ncbi.nlm.nih.gov/34315040
https://doi.org/10.1016/j.ejmech.2021.113711
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language English
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title The synthesis and bioactivity of pyrrolo[2,3-d]pyrimidine derivatives as tyrosine kinase inhibitors for NSCLC cells with EGFR mutations
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770248_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770179_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770186_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770188_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770202_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770226_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770168_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770246_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770184_PMID34315040_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770244_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770187_PMID34315040_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770173_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770201_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770171_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770193_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770205_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770203_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770169_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770251_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770194_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770183_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770204_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770170_PMID34315040_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770217_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770247_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770169_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770205_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770193_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770196_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770208_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770171_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770204_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770182_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770218_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770237_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770177_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770200_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770249_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770241_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770198_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770182_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770244_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770214_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770189_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770227_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770251_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770233_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770233_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770212_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770205_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770252_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770191_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770185_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770245_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770197_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770172_PMID34315040_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770198_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770211_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770240_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770249_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770166_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770191_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806781_AID1770172_PMID34315040_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770172_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770166_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770232_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770252_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770216_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770202_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770244_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770176_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770218_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770217_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770192_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770186_PMID34315040_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770202_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770197_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770250_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770170_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770221_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770217_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770203_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770209_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770173_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770242_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770173_PMID34315040_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770208_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806781_AID1770187_PMID34315040_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770207_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770187_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770183_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770225_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770208_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID336872724_AID1770169_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770174_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770187_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770189_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770221_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770238_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770174_PMID34315040_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770228_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770225_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770231_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770242_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770166_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770234_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770172_PMID34315040_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770182_PMID34315040_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770210_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770211_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770181_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770225_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770195_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770248_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770183_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806781_AID1770169_PMID34315040_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770250_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770236_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806781_AID1770184_PMID34315040_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770195_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770185_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770181_PMID34315040_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770168_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770174_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770170_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770251_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770171_PMID34315040_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469821437_AID1770172_PMID34315040_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770195_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770245_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770175_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770187_PMID34315040_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469819429_AID1770184_PMID34315040_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770219_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806781_AID1770182_PMID34315040_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770203_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770237_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770227_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770187_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770206_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770174_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770192_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770218_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770216_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770201_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770219_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806781_AID1770186_PMID34315040_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770199_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770237_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798701_AID1770182_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID336872724_AID1770185_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770212_PMID34315040_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469801702_AID1770224_PMID34315040_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770241_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807702_AID1770239_PMID34315040_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404719202_AID1770199_PMID34315040_VALUE1
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5603
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5600
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6300
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5595
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5594
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6198
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1956
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6774
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1432

Total number of triples: 396.