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endingPage 9499
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1520-4804
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publicationName Journal of Medicinal Chemistry
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bibliographicCitation Mackman RL, Steadman VA, Dean DK, Jansa P, Poullennec KG, Appleby T, Austin C, Blakemore CA, Cai R, Cannizzaro C, Chin G, Chiva JC, Dunbar NA, Fliri H, Highton AJ, Hui H, Ji M, Jin H, Karki K, Keats AJ, Lazarides L, Lee YJ, Liclican A, Mish M, Murray B, Pettit SB, Pyun P, Sangi M, Santos R, Sanvoisin J, Schmitz U, Schrier A, Siegel D, Sperandio D, Stepan G, Tian Y, Watt GM, Yang H, Schultz BE. Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. J Med Chem. 2018 Nov 08;61(21):9473–99. doi: 10.1021/acs.jmedchem.8b00802. PMID: 30074795.
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date 2018-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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title Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662607_AID1362385_PMID30074795_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404654190_AID1362388_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404654190_AID1362395_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662607_AID1362408_PMID30074795_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661550_AID1362388_PMID30074795_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661550_AID1362394_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362393_PMID30074795_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666929_AID1362387_PMID30074795_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404654190_AID1362387_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103230651_AID1362386_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666929_AID1362386_PMID30074795_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657063_AID1362391_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404655179_AID1362395_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362385_PMID30074795_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404653507_AID1362395_PMID30074795_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657063_AID1362387_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661550_AID1362390_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661955_AID1362390_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362389_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662607_AID1362386_PMID30074795_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362385_PMID30074795_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362395_PMID30074795_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404653507_AID1362391_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666929_AID1362396_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662477_AID1362385_PMID30074795_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362414_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404655179_AID1362396_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362396_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103230651_AID1362388_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362394_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666852_AID1362393_PMID30074795_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661550_AID1362408_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666852_AID1362397_PMID30074795_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362388_PMID30074795_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362389_PMID30074795_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362385_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362397_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661955_AID1362388_PMID30074795_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657825_AID1362390_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657825_AID1362394_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661955_AID1362391_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362395_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362397_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404653507_AID1362397_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362389_PMID30074795_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404653507_AID1362387_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362412_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362387_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404653507_AID1362400_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664481_AID1362391_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362394_PMID30074795_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661955_AID1362392_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362389_PMID30074795_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362393_PMID30074795_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362396_PMID30074795_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657825_AID1362391_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362389_PMID30074795_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404654190_AID1362385_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362394_PMID30074795_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661550_AID1362392_PMID30074795_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657063_AID1362393_PMID30074795_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404654190_AID1362393_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661550_AID1362393_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404659242_AID1362387_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666929_AID1362389_PMID30074795_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652516_AID1362394_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362408_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362387_PMID30074795_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404661955_AID1362387_PMID30074795_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362413_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362386_PMID30074795_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381845477_AID1362385_PMID30074795_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657825_AID1362409_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404653507_AID1362402_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103221020_AID1362385_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404660125_AID1362387_PMID30074795_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657825_AID1362395_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404659242_AID1362388_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362391_PMID30074795_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362395_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362395_PMID30074795_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657063_AID1362395_PMID30074795_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652516_AID1362393_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362386_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657825_AID1362388_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103230651_AID1362387_PMID30074795_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664481_AID1362386_PMID30074795_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362386_PMID30074795_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666929_AID1362394_PMID30074795_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362386_PMID30074795_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664169_AID1362393_PMID30074795_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664481_AID1362390_PMID30074795_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362405_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652516_AID1362389_PMID30074795_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404686972_AID1362385_PMID30074795_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362397_PMID30074795_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404657063_AID1362388_PMID30074795_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652337_AID1362388_PMID30074795_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652516_AID1362386_PMID30074795_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362393_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404652516_AID1362385_PMID30074795_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404664481_AID1362395_PMID30074795_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404666852_AID1362396_PMID30074795_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662477_AID1362386_PMID30074795_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404662546_AID1362391_PMID30074795_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404659242_AID1362386_PMID30074795_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362394_PMID30074795_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID404658414_AID1362388_PMID30074795_VALUE9
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5478
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8856

Total number of triples: 333.