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bibliographicCitation Aylott HE, Atkinson SJ, Bamborough P, Bassil A, Chung CW, Gordon L, Grandi P, Gray JRJ, Harrison LA, Hayhow TG, Messenger C, Mitchell D, Phillipou A, Preston A, Prinjha RK, Rianjongdee F, Rioja I, Seal JT, Wall ID, Watson RJ, Woolven JM, Demont EH. Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors. J Med Chem. 2021 Mar 25;64(6):3249–81. doi: 10.1021/acs.jmedchem.0c02156. PMID: 33662213.
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date 2021-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
identifier https://pubmed.ncbi.nlm.nih.gov/33662213
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language English
source https://pubmed.ncbi.nlm.nih.gov/
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title Template-Hopping Approach Leads to Potent, Selective, and Highly Soluble Bromo and Extraterminal Domain (BET) Second Bromodomain (BD2) Inhibitors
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775613_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827939_AID1775606_PMID33662213_VALUE48
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775629_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806466_AID1775606_PMID33662213_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803968_AID1775607_PMID33662213_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812797_AID1775609_PMID33662213_VALUE28
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815129_AID1775609_PMID33662213_VALUE34
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804962_AID1775606_PMID33662213_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775616_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806561_AID1775604_PMID33662213_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775622_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775616_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775624_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775622_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827217_AID1775605_PMID33662213_VALUE47
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805807_AID1775604_PMID33662213_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806466_AID1775609_PMID33662213_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808807_AID1775609_PMID33662213_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469818860_AID1775605_PMID33662213_VALUE42
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812231_AID1775606_PMID33662213_VALUE29
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814370_AID1775606_PMID33662213_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775610_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806817_AID1775605_PMID33662213_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806659_AID1775605_PMID33662213_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775612_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814801_AID1775609_PMID33662213_VALUE33
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804570_AID1775606_PMID33662213_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442049255_AID1775606_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469800372_AID1775606_PMID33662213_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827217_AID1775606_PMID33662213_VALUE47
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775622_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775623_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469818860_AID1775606_PMID33662213_VALUE42
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799874_AID1775606_PMID33662213_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775618_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469826672_AID1775605_PMID33662213_VALUE45
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827939_AID1775605_PMID33662213_VALUE48
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442052558_AID1775609_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775610_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808807_AID1775606_PMID33662213_VALUE25
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442052558_AID1775605_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775613_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469809013_AID1775606_PMID33662213_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827063_AID1775606_PMID33662213_VALUE46
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775617_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803558_AID1775609_PMID33662213_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799796_AID1775605_PMID33662213_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814681_AID1775605_PMID33662213_VALUE36
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469809013_AID1775605_PMID33662213_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469811347_AID1775604_PMID33662213_VALUE28
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814801_AID1775608_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806561_AID1775607_PMID33662213_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775617_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803801_AID1775605_PMID33662213_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815129_AID1775607_PMID33662213_VALUE38
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804906_AID1775607_PMID33662213_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812797_AID1775607_PMID33662213_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775605_PMID33662213_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805327_AID1775607_PMID33662213_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828457_AID1775605_PMID33662213_VALUE49
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805807_AID1775609_PMID33662213_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469818843_AID1775606_PMID33662213_VALUE41
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814801_AID1775606_PMID33662213_VALUE37
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775618_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812447_AID1775605_PMID33662213_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812231_AID1775605_PMID33662213_VALUE29
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806659_AID1775607_PMID33662213_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775624_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775617_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469809013_AID1775609_PMID33662213_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775628_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814681_AID1775606_PMID33662213_VALUE36
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820774_AID1775604_PMID33662213_VALUE44
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799796_AID1775606_PMID33662213_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813605_AID1775607_PMID33662213_VALUE34
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775627_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442052558_AID1775606_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807606_AID1775606_PMID33662213_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828534_AID1775606_PMID33662213_VALUE50
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804570_AID1775604_PMID33662213_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803567_AID1775609_PMID33662213_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803567_AID1775604_PMID33662213_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469811347_AID1775607_PMID33662213_VALUE28
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812797_AID1775604_PMID33662213_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775621_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805327_AID1775604_PMID33662213_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812336_AID1775605_PMID33662213_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442049255_AID1775609_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806659_AID1775609_PMID33662213_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775614_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807951_AID1775607_PMID33662213_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805807_AID1775605_PMID33662213_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775606_PMID33662213_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827217_AID1775607_PMID33662213_VALUE47
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806817_AID1775607_PMID33662213_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812447_AID1775609_PMID33662213_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812336_AID1775607_PMID33662213_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827063_AID1775604_PMID33662213_VALUE46
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828457_AID1775609_PMID33662213_VALUE43
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775619_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775605_PMID33662213_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469818610_AID1775604_PMID33662213_VALUE40
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812336_AID1775604_PMID33662213_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814681_AID1775609_PMID33662213_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775624_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469800372_AID1775604_PMID33662213_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775609_PMID33662213_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807606_AID1775604_PMID33662213_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815551_AID1775607_PMID33662213_VALUE39
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775607_PMID33662213_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469805327_AID1775609_PMID33662213_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775620_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803558_AID1775605_PMID33662213_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803801_AID1775609_PMID33662213_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806817_AID1775604_PMID33662213_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804906_AID1775609_PMID33662213_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806659_AID1775606_PMID33662213_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469798577_AID1775607_PMID33662213_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828534_AID1775609_PMID33662213_VALUE44
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461551817_AID1775604_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812447_AID1775604_PMID33662213_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469813360_AID1775606_PMID33662213_VALUE33
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804906_AID1775605_PMID33662213_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469812797_AID1775606_PMID33662213_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806466_AID1775607_PMID33662213_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814370_AID1775605_PMID33662213_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807951_AID1775604_PMID33662213_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804906_AID1775606_PMID33662213_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807951_AID1775605_PMID33662213_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775610_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814681_AID1775607_PMID33662213_VALUE36
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469815551_AID1775606_PMID33662213_VALUE39
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469811152_AID1775607_PMID33662213_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469828457_AID1775606_PMID33662213_VALUE49
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469839346_AID1775609_PMID33662213_VALUE45
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775611_PMID33662213_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469808807_AID1775605_PMID33662213_VALUE25
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804570_AID1775605_PMID33662213_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469807606_AID1775609_PMID33662213_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469803567_AID1775607_PMID33662213_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469826672_AID1775607_PMID33662213_VALUE45
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469826672_AID1775604_PMID33662213_VALUE45
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820774_AID1775606_PMID33662213_VALUE44
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806561_AID1775609_PMID33662213_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804906_AID1775604_PMID33662213_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469827217_AID1775609_PMID33662213_VALUE41
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469820675_AID1775607_PMID33662213_VALUE43
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775628_PMID33662213_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799796_AID1775609_PMID33662213_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806623_AID1775607_PMID33662213_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469818860_AID1775604_PMID33662213_VALUE42
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469806561_AID1775605_PMID33662213_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469814801_AID1775605_PMID33662213_VALUE37
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804962_AID1775607_PMID33662213_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469799874_AID1775607_PMID33662213_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID469804265_AID1775627_PMID33662213_VALUE1
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID213
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6046
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3757
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID676
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8019

Total number of triples: 380.