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bibliographicCitation Gonzalez-Lopez de Turiso F, Hao X, Shin Y, Bui M, Campuzano IDG, Cardozo M, Dunn MC, Duquette J, Fisher B, Foti RS, Henne K, He X, Hu Y, Kelly RC, Johnson MG, Lucas BS, McCarter J, McGee LR, Medina JC, Metz D, San Miguel T, Mohn D, Tran T, Vissinga C, Wannberg S, Whittington DA, Whoriskey J, Yu G, Zalameda L, Zhang X, Cushing TD. Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-1430). J. Med. Chem. 2016 Jul 25;59(15):7252–67. doi: 10.1021/acs.jmedchem.6b00827.
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title Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-1430)
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440229968_AID1628651_PMID27411843_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628659_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628655_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628653_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628668_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125438_AID1628663_PMID27411843_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628672_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628657_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628661_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628658_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628656_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628653_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628658_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125240_AID1628663_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628660_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628651_PMID27411843_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628657_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628651_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628667_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628650_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125240_AID1628658_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125438_AID1628654_PMID27411843_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628658_PMID27411843_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628656_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628653_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628662_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628656_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628665_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628662_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628663_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID312383465_AID1628655_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628658_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628663_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628662_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628664_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628661_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628667_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628651_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440229968_AID1628658_PMID27411843_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628657_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440113847_AID1628661_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125240_AID1628650_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628652_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440113847_AID1628653_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628654_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628655_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628661_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628666_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628663_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125438_AID1628651_PMID27411843_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628669_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628653_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628654_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628658_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628656_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628666_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440229968_AID1628662_PMID27411843_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628664_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628651_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628660_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628654_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628673_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628656_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628669_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628667_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628659_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628659_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628653_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628654_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628663_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628674_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628659_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628661_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID312383465_AID1628651_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628650_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628655_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628670_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628674_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628662_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628673_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628659_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628654_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628655_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628656_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125438_AID1628660_PMID27411843_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628662_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID312383465_AID1628656_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628654_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628650_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628666_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440113847_AID1628652_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125240_AID1628652_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628659_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628663_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125438_AID1628659_PMID27411843_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628652_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628651_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628655_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628676_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628658_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628657_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628667_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628660_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440229968_AID1628652_PMID27411843_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628659_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628657_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628658_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628654_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628655_PMID27411843_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628654_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628652_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440213736_AID1628651_PMID27411843_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628661_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628663_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628677_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628662_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628668_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125240_AID1628655_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440139833_AID1628651_PMID27411843_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440113847_AID1628656_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628655_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628651_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125438_AID1628661_PMID27411843_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628657_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628652_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628660_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628652_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440198633_AID1628663_PMID27411843_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440137518_AID1628663_PMID27411843_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628674_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628676_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440113847_AID1628657_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118314_AID1628650_PMID27411843_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID312383465_AID1628659_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628661_PMID27411843_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID312383465_AID1628654_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440185013_AID1628660_PMID27411843_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628661_PMID27411843_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440113847_AID1628660_PMID27411843_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440216559_AID1628652_PMID27411843_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440163440_AID1628660_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID312383465_AID1628652_PMID27411843_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440125240_AID1628660_PMID27411843_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440229968_AID1628650_PMID27411843_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628653_PMID27411843_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628659_PMID27411843_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440145851_AID1628659_PMID27411843_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440118772_AID1628657_PMID27411843_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440156812_AID1628655_PMID27411843_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID405270467_AID1628652_PMID27411843_VALUE2
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID8856
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5291
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5290
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5293
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID18707
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5294
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1565
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1576

Total number of triples: 376.