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endingPage 13594
issn 0022-2623
1520-4804
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publicationName Journal of Medicinal Chemistry
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bibliographicCitation LaMarche MJ, Acker M, Argintaru A, Bauer D, Boisclair J, Chan H, Chen CH, Chen YN, Chen Z, Deng Z, Dore M, Dunstan D, Fan J, Fekkes P, Firestone B, Fodor M, Garcia-Fortanet J, Fortin PD, Fridrich C, Giraldes J, Glick M, Grunenfelder D, Hao HX, Hentemann M, Ho S, Jouk A, Kang ZB, Karki R, Kato M, Keen N, Koenig R, LaBonte LR, Larrow J, Liu G, Liu S, Majumdar D, Mathieu S, Meyer MJ, Mohseni M, Ntaganda R, Palermo M, Perez L, Pu M, Ramsey T, Reilly J, Sarver P, Sellers WR, Sendzik M, Shultz MD, Slisz J, Slocum K, Smith T, Spence S, Stams T, Straub C, Tamez V, Toure BB, Towler C, Wang P, Wang H, Williams SL, Yang F, Yu B, Zhang JH, Zhu S. Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer. J Med Chem. 2020 Nov 25;63(22):13578–94. doi: 10.1021/acs.jmedchem.0c01170. PMID: 32910655.
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date 2020-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
identifier https://doi.org/10.1021/acs.jmedchem.0c01170
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https://portal.issn.org/resource/ISSN/1520-4804
language English
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https://pubmed.ncbi.nlm.nih.gov/
title Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461524081_AID1697077_PMID32910655_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697115_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697069_PMID32910655_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461519515_AID1697078_PMID32910655_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697114_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697067_PMID32910655_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697123_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532073_AID1697067_PMID32910655_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461519515_AID1697066_PMID32910655_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160708513_AID1697076_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461519515_AID1697067_PMID32910655_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461524081_AID1697067_PMID32910655_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697100_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532436_AID1697067_PMID32910655_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461548426_AID1697078_PMID32910655_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461526793_AID1697080_PMID32910655_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697078_PMID32910655_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697111_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461548426_AID1697069_PMID32910655_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461526793_AID1697066_PMID32910655_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461531495_AID1697069_PMID32910655_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697090_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697106_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461537750_AID1697071_PMID32910655_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539934_AID1697078_PMID32910655_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697121_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461521213_AID1697077_PMID32910655_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697098_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461517100_AID1697069_PMID32910655_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461559319_AID1697066_PMID32910655_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461559319_AID1697080_PMID32910655_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381842551_AID1697071_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461519515_AID1697079_PMID32910655_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461537750_AID1697078_PMID32910655_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440208833_AID1697067_PMID32910655_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461521213_AID1697069_PMID32910655_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440200175_AID1697074_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461531495_AID1697067_PMID32910655_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440128776_AID1697067_PMID32910655_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697078_PMID32910655_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461516235_AID1697079_PMID32910655_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697104_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697088_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461517100_AID1697078_PMID32910655_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461519515_AID1697077_PMID32910655_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461531495_AID1697078_PMID32910655_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532436_AID1697069_PMID32910655_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697112_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461556923_AID1697069_PMID32910655_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697066_PMID32910655_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461531495_AID1697080_PMID32910655_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461556923_AID1697066_PMID32910655_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697124_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697079_PMID32910655_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539934_AID1697080_PMID32910655_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461559319_AID1697077_PMID32910655_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532436_AID1697077_PMID32910655_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440211622_AID1697067_PMID32910655_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697080_PMID32910655_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697070_PMID32910655_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539934_AID1697066_PMID32910655_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697066_PMID32910655_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461524081_AID1697066_PMID32910655_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461537750_AID1697066_PMID32910655_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461548426_AID1697066_PMID32910655_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697097_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381842551_AID1697069_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381842551_AID1697070_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697085_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461526793_AID1697069_PMID32910655_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697119_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697083_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461516235_AID1697078_PMID32910655_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461519515_AID1697080_PMID32910655_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461551618_AID1697066_PMID32910655_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461537750_AID1697081_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697096_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440211340_AID1697065_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440154443_AID1697068_PMID32910655_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461517100_AID1697067_PMID32910655_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697099_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461559319_AID1697078_PMID32910655_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440175180_AID1697072_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532073_AID1697069_PMID32910655_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697080_PMID32910655_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461539349_AID1697077_PMID32910655_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381842551_AID1697077_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461537750_AID1697079_PMID32910655_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID440199283_AID1697067_PMID32910655_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461556923_AID1697077_PMID32910655_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381842551_AID1697066_PMID32910655_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461524081_AID1697069_PMID32910655_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461521213_AID1697079_PMID32910655_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697091_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697069_PMID32910655_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461524081_AID1697078_PMID32910655_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461551618_AID1697077_PMID32910655_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461548426_AID1697079_PMID32910655_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID442046361_AID1697105_PMID32910655_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461548426_AID1697080_PMID32910655_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532073_AID1697080_PMID32910655_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160708513_AID1697066_PMID32910655_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461532436_AID1697080_PMID32910655_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID461551618_AID1697079_PMID32910655_VALUE16
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1565
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3845
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1559
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1576
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID472319190
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5605
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5604
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID673
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5781
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3757
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1956

Total number of triples: 333.