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Roumen L, Peeters JW, Emmen JMA, Beugels IPE, Custers EMG, de Gooyer M, Plate R, Pieterse K, Hilbers PAJ, Smits JFM, Vekemans JAJ, Leysen D, Ottenheijm HCJ, Janssen HM, Hermans JJR. Synthesis, Biological Evaluation, and Molecular Modeling of 1-Benzyl-1H-imidazoles as Selective Inhibitors of Aldosterone Synthase (CYP11B2). J. Med. Chem. 2010 Feb 01;53(4):1712–25. doi: 10.1021/jm901356d. |