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contentType Journal Article
endingPage 913
issn 0022-2623
1520-4804
issueIdentifier 2
pageRange 903-913
publicationName Journal of Medicinal Chemistry
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bibliographicCitation Hudkins RL, Becknell NC, Zulli AL, Underiner TL, Angeles TS, Aimone LD, Albom MS, Chang H, Miknyoczki SJ, Hunter K, Jones-Bolin S, Zhao H, Bacon ER, Mallamo JP, Ator MA, Ruggeri BA. Synthesis and biological profile of the pan-vascular endothelial growth factor receptor/tyrosine kinase with immunoglobulin and epidermal growth factor-like homology domains 2 (VEGF-R/TIE-2) inhibitor 11-(2-methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one (CEP-11981): a novel oncology therapeutic agent. J Med Chem. 2012 Jan 26;55(2):903–13. doi: 10.1021/jm201449n. PMID: 22148921.
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date 2012-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
identifier https://doi.org/10.1021/jm201449n
https://pubmed.ncbi.nlm.nih.gov/22148921
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language English
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title Synthesis and Biological Profile of the pan-Vascular Endothelial Growth Factor Receptor/Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor-Like Homology Domains 2 (VEGF-R/TIE-2) Inhibitor 11-(2-Methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one (CEP-11981): A Novel Oncology Therapeutic Agent
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653789_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160672020_AID653553_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653719_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653959_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653746_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693474_AID653551_PMID22148921_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653726_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653580_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160688015_AID653550_PMID22148921_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653550_PMID22148921_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653552_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653758_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653556_PMID22148921_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653739_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693474_AID653550_PMID22148921_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653779_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653729_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653767_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160672019_AID653549_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653955_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID249565869_AID1345548_PMID22148921_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704206_AID653549_PMID22148921_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160672021_AID653551_PMID22148921_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653749_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160672020_AID653549_PMID22148921_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653725_PMID22148921_VALUE1
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160688043_AID653550_PMID22148921_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653956_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653780_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653968_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653751_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693474_AID653549_PMID22148921_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653755_PMID22148921_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653761_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653561_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653965_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653953_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653962_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653772_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653560_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID249565869_AID1345545_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653738_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653754_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653731_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653957_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653740_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103396542_AID653550_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653940_PMID22148921_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693473_AID653549_PMID22148921_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160704205_AID653722_PMID22148921_VALUE1
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID140
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6869
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2321
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2322
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID695
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2209
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6714
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1956
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5156
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3717
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6885
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7182
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1436
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID640
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4914
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5979
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4915
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3757
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID207
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1452
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7010
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1129
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1557
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4233
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID323154297
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID135
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11200
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1132
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6865
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2260
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2261
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID238
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6788
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1576
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2932
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6790
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1565
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12143
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID249565869
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3791
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID185

Total number of triples: 324.