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Katayama K, Tsunemi T, Miyazaki K, Uoto K, Yoshioka R, Terashima H, Terakawa M, Yamashiro K, Haruyama M, Maeda H, Makino T. Design, synthesis, and optimization of a series of 2-azaspiro[3.3]heptane derivatives as orally bioavailable fetal hemoglobin inducers. Bioorganic & Medicinal Chemistry Letters. 2020 Oct;30(19):127425. doi: 10.1016/j.bmcl.2020.127425. |