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bibliographicCitation Gilson PR, Tan C, Jarman KE, Lowes KN, Curtis JM, Nguyen W, Di Rago AE, Bullen HE, Prinz B, Duffy S, Baell JB, Hutton CA, Jousset Subroux H, Crabb BS, Avery VM, Cowman AF, Sleebs BE. Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity. J Med Chem. 2017 Feb 09;60(3):1171–88. doi: 10.1021/acs.jmedchem.6b01673. PMID: 28080063.
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date 2017-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
identifier https://pubmed.ncbi.nlm.nih.gov/28080063
https://doi.org/10.1021/acs.jmedchem.6b01673
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https://portal.issn.org/resource/ISSN/1520-4804
language English
source https://www.crossref.org/
https://pubmed.ncbi.nlm.nih.gov/
title Optimization of 2-Anilino 4-Amino Substituted Quinazolines into Potent Antimalarial Agents with Oral in Vivo Activity
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http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431585_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431596_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431580_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381886886_AID1431576_PMID28080063_VALUE56
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869848_AID1431577_PMID28080063_VALUE43
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872105_AID1431576_PMID28080063_VALUE47
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381873339_AID1431577_PMID28080063_VALUE48
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431582_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431587_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103169732_AID1431582_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431578_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431605_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431575_PMID28080063_VALUE29
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431573_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381837614_AID1431575_PMID28080063_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381842103_AID1431576_PMID28080063_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431582_PMID28080063_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431597_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693248_AID1431575_PMID28080063_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381853457_AID1431576_PMID28080063_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431591_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381837614_AID1431577_PMID28080063_VALUE18
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381838956_AID1431577_PMID28080063_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381878175_AID1431577_PMID28080063_VALUE50
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381865074_AID1431575_PMID28080063_VALUE40
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431575_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109589_AID1431577_PMID28080063_VALUE13
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431587_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431606_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381840588_AID1431582_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431596_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID163322661_AID1431582_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431599_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431579_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103169732_AID1431585_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431581_PMID28080063_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381873339_AID1431575_PMID28080063_VALUE51
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381881389_AID1431577_PMID28080063_VALUE52
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381881389_AID1431576_PMID28080063_VALUE53
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID163322661_AID1431587_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID336897396_AID1431575_PMID28080063_VALUE19
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966209_AID1431577_PMID28080063_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431589_PMID28080063_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109589_AID1431576_PMID28080063_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381840588_AID1431575_PMID28080063_VALUE24
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431600_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431583_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431587_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381850491_AID1431576_PMID28080063_VALUE29
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431574_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431575_PMID28080063_VALUE50
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381857688_AID1431575_PMID28080063_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103715211_AID1431577_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431597_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431576_PMID28080063_VALUE48
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109008_AID1431575_PMID28080063_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431600_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242412286_AID1431576_PMID28080063_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431602_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103210597_AID1431588_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381848421_AID1431575_PMID28080063_VALUE28
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381852905_AID1431577_PMID28080063_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381857688_AID1431577_PMID28080063_VALUE32
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381861918_AID1431577_PMID28080063_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID104234176_AID1431576_PMID28080063_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID336897397_AID1431575_PMID28080063_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869848_AID1431576_PMID28080063_VALUE44
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431573_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431590_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381852905_AID1431575_PMID28080063_VALUE33
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID336897397_AID1431577_PMID28080063_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866533_AID1431577_PMID28080063_VALUE38
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381858331_AID1431576_PMID28080063_VALUE34
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431576_PMID28080063_VALUE42
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869873_AID1431575_PMID28080063_VALUE47
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693248_AID1431584_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381878175_AID1431576_PMID28080063_VALUE51
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103714308_AID1431576_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431581_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431594_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431574_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869873_AID1431576_PMID28080063_VALUE45
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872105_AID1431577_PMID28080063_VALUE46
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431598_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431588_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381861918_AID1431575_PMID28080063_VALUE38
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431579_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431592_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869090_AID1431576_PMID28080063_VALUE43
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431574_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381839797_AID1431577_PMID28080063_VALUE20
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431581_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431576_PMID28080063_VALUE28
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381841241_AID1431577_PMID28080063_VALUE22
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103169732_AID1431589_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431596_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871841_AID1431582_PMID28080063_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103710569_AID1431577_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693248_AID1431586_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103710569_AID1431576_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109474_AID1431575_PMID28080063_VALUE14
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381878175_AID1431575_PMID28080063_VALUE53
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431575_PMID28080063_VALUE43
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109474_AID1431576_PMID28080063_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109580_AID1431577_PMID28080063_VALUE12
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381861585_AID1431576_PMID28080063_VALUE35
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431573_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431585_PMID28080063_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109076_AID1431576_PMID28080063_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431585_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381865074_AID1431576_PMID28080063_VALUE38
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103714308_AID1431575_PMID28080063_VALUE7
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109076_AID1431577_PMID28080063_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866533_AID1431575_PMID28080063_VALUE41
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103169732_AID1431588_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID124966209_AID1431576_PMID28080063_VALUE9
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431601_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431579_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431589_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431604_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866713_AID1431577_PMID28080063_VALUE39
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431604_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431590_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381885317_AID1431582_PMID28080063_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431575_PMID28080063_VALUE30
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431605_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381853457_AID1431577_PMID28080063_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103709792_AID1431580_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431601_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381881389_AID1431575_PMID28080063_VALUE55
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431577_PMID28080063_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381852905_AID1431576_PMID28080063_VALUE31
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431583_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431574_PMID28080063_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381871841_AID1431575_PMID28080063_VALUE48
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381843335_AID1431575_PMID28080063_VALUE27
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381839797_AID1431575_PMID28080063_VALUE23
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431600_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431581_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431579_PMID28080063_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431574_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849375_AID1431593_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381858331_AID1431575_PMID28080063_VALUE36
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381872696_AID1431583_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103210597_AID1431589_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381857688_AID1431576_PMID28080063_VALUE33
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103714308_AID1431577_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431598_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID336897396_AID1431577_PMID28080063_VALUE16
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381853457_AID1431575_PMID28080063_VALUE34
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869848_AID1431578_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109837_AID1431575_PMID28080063_VALUE17
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103169732_AID1431575_PMID28080063_VALUE1
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431597_PMID28080063_VALUE5
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381839797_AID1431576_PMID28080063_VALUE21
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431577_PMID28080063_VALUE26
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381866862_AID1431598_PMID28080063_VALUE3
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381877447_AID1431582_PMID28080063_VALUE10
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103713206_AID1431577_PMID28080063_VALUE4
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID160693248_AID1431585_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381869848_AID1431574_PMID28080063_VALUE6
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID242109580_AID1431575_PMID28080063_VALUE15
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381849324_AID1431580_PMID28080063_VALUE2
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID163322661_AID1431575_PMID28080063_VALUE11
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID103715211_AID1431575_PMID28080063_VALUE8
http://rdf.ncbi.nlm.nih.gov/pubchem/endpoint/SID381867533_AID1431575_PMID28080063_VALUE44

Total number of triples: 387.